Clinical trials: Cancer Pains, open to volunteers
Oral Mucositis, Quality of Life
Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.
The use of a novel topical mucosa composition (XCM-OM118) comprising 2-(trimethylazaniumyl) acetate; (2R,3R,4S)-pentane-1,2,3,4,5-pentol; Hexadecanoic acid; (9Z, 12Z)-octadeca-9,12-dienoic acid; octadecanoic acid…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- STOPOMP (NCT05635929)
- Testing
- XCM-OM118 Composition comprising olive oil, betaine and xylitol
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Mucosa Innovations, S.L.
Advanced Cancer, Pain
Integrated Smartphone Technology to Alleviate Malignant Pain (I-STAMP) Testing
The purpose of the study is to evaluate if the smartphone app, I-STAMP (Integrated Smartphone Technology to Alleviate Malignant Pain), helps participants with cancer pain manage symptoms and keep track of medications.
- Trial name
- NCT06117709
- Testing
- I-STAMP
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Dana-Farber Cancer Institute
Breasts - Female, Breast Cancer
Effects of a Pilates Studio Program on Quality of Life and Functional Capacity of Women Undergoing Breast Cancer Treatment
Introduction: Cancer treatment generates undesirable effects, directly affecting the functional and psychosocial capacity faced by breast cancer patients during treatment.
- Conditions
- Breasts - Female, Breast Cancer, Breast Cancer in Women
- Trial name
- Cancer (NCT07599098)
- Testing
- Pilates Studio Program Group
- Volunteers
- 50 people
- Sponsor
- Federal University of Maranhao
Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF)
Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain Relief
This study will test whether gentle electrical stimulation to nerves near the uterus can reduce pelvic pain after uterine fibroid embolization.
- Conditions
- Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF), Uterine Fibroids, Pelvic Pain
- Trial name
- TUNES (NCT07501676)
- Testing
- TUNES (Transmucosal Uterosacral Electrical Stimulation)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Colorectal Carcinoma, Analgesia, Postoperative
Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing…
- Conditions
- Colorectal Carcinoma, Analgesia, Postoperative, Laparotomy
- Trial name
- NCT06935708
- Testing
- Intrathecal Morphine, Epidural Analgesia
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- Meri Mirceta
Intrathecal Drug Delivery, Refractory Cancer Pain
Intrathecal Therapy Versus Standard Care for Severe Cancer Pain
Approximately 66% of patients with advanced cancer experience pain, which is often inadequately controlled and associated with a decline in health-related quality of life (HRQoL).
- Conditions
- Intrathecal Drug Delivery, Refractory Cancer Pain, Conventional Medical Management
- Trial name
- CAREGIVER (NCT07691840)
- Testing
- Intrathecal Drug Delivery, Comprehensive Medical Management
- Where
- Belgium
- Volunteers
- 72 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Cancer, Post Operative Pain
Perioperative Mirogabalin for Pain Relief After Modified Radical Mastectomy
This study aims to evaluate whether perioperative mirogabalin can reduce postoperative pain and morphine consumption in female patients undergoing modified radical mastectomy for breast cancer.
- Trial name
- NCT07880821
- Testing
- Mirogabalin
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cancer, Pain
Cancer Pain 101: A Digital, Asynchronous Intervention of Pain Management in Advanced Cancer
This is a Stage 1 study of a behavioral intervention, which means that a new intervention is being pilot tested to understand whether it is acceptable and feasible for people with advanced cancer to use.
- Conditions
- Cancer, Pain, Advanced Cancer
- Trial name
- COPES Aim 3 (NCT07852468)
- Testing
- Cancer Pain 101
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Alabama at Birmingham
Burns, Acute Pain
VR-PAT During Home Burn Dressings - Multisite
This study will evaluate the effectiveness of smartphone Virtual Reality Pain Alleviation Therapy (VR-PAT) as a pain distraction tool during repeated at-home burn dressing changes among 100 children (age 6-17 years) with a burn…
- Conditions
- Burns, Acute Pain, Procedural Pain, Injuries
- Trial name
- NCT05673551
- Testing
- VR-PAT
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Nationwide Children's Hospital
Laughter Yoga
The Effect of Laughter Yoga on Pain, Fatigue, and General Well-Being in Cancer Patients and Their Caregivers
This study aims to evaluate the effect of laughter yoga on pain, fatigue, and general well-being in cancer patients and their caregivers.
- Trial name
- NCT06995248
- Testing
- Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Breast Cancer, Neuropathic Pain in Cancer
Effect of Aromatherapy on the Management of Chemotherapy-Induced Neuropathy (CIN)
The main objective of this study is to describe the effect of an essential oil-based blend applied topically in the management of painful symptoms, sensory disturbances, or functional impairment caused by Chemotherapy-Induced…
- Trial name
- AROMA NEUROTAX (NCT07779135)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier de Colmar
Hematologic Malignancy, Neutropenia
Comparing Diosmin-Hesperidin and Loratadine to Prevent Bone Pain From G-CSF in Patients With Blood Cancers
This is a comparative interventional study to determine the best way to prevent G-CSF induced bone pain in patients with hematological malignancies (blood cancers).
- Conditions
- Hematologic Malignancy, Neutropenia, Bone Pain
- Trial name
- NCT07300735
- Testing
- Loratadine, Diosmin-Hesperidin, Loratadine + Diosmin-Hesperidin
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Alexandria University
Breast Cancer, Postoperative Pain
Ultrasound-Guided SPSIP Versus ESPB for Postoperative Pain After Modified Radical Mastectomy
Breast cancer is the most common cancer affecting women worldwide. Modified radical mastectomy is one of the main surgical treatments for breast cancer.
- Conditions
- Breast Cancer, Postoperative Pain, Acute Post-surgical Pain
- Trial name
- SPSIP-ESPB (NCT07446868)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cancer Pain
3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain
This study aims to evaluate the safety and efficacy of 3D1002 alone or in combination with oxycodone hydrochloride sustained-release tablets (OxyContin) for the management of moderate or severe cancer pain.
- Trial name
- NCT05265052
- Testing
- 3D1002 (50 mg)(Phase IIa), 3D1002 (100 mg)(Phase IIa), 3D1002 (150 mg)(Phase IIa)
- Volunteers
- 177 people
- Sponsor
- 3D Medicines
Women Following Unilateral Mastectomy
Shoulder Exercise Training on Pain, Range of Motion, and Functional Limitations in Women Following Unilateral Mastectomy
Shoulder pain, reduced mobility, and functional limitations are common complications following unilateral mastectomy, often leading to long-term disability and an increased risk of secondary shoulder-hand syndrome
- Trial name
- NCT07478718
- Testing
- Interventions 1. Scapular and Shoulder Exercise Program (Intervention Group) Supervision and Duration • 3 sessions/week • 45-60 minutes per session • Total duration: 8 weeks (24 sessions) • Conducted
- Where
- Jordan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- South Valley University
Cancer Pain
RAD ONC FREEDOM Oncology Pain
The investigators propose to conduct a study in medically refractory cancer pain patients utilizing radiosurgery to ablate the pituitary hypophysis, as well as neuromodulate the centromedian and parafascicular complexes within…
- Trial name
- FREEDOM (NCT07605546)
- Testing
- Radiosurgery
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Polycystic Ovarian Syndrome
Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.
The study will be a non-blinded randomized controlled trial, consisting of two groups. Non-probability Convenience sampling will be used to recruit participants who will meet the inclusion criteria.
- Trial name
- NCT07645014
- Testing
- Neurodynamic stretches, myofascial pain release technique Interventions:
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Endometrial Carcinoma
Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain
This phase IV trial studies whether low dose aspirin can be used to lower inflammation and prevent endometrial cancer in postmenopausal women with changes in the endometrial tissue that are not related to thinning (non-atrophic…
- Trial name
- NCT07281547
- Testing
- Biospecimen Collection, Low-Dose Aspirin, Patient Observation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer, Postoperative Pain
Single vs Multiple Injection Intertransverse Process Block in Breast Cancer Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of single Intertransverse Process Block (ITP) and multiple Intertransverse Process Block (ITP) in patients undergoing Breast Cancer Surgery.
- Conditions
- Breast Cancer, Postoperative Pain, Mastectomy, Regional Anaesthesia
- Trial name
- NCT07763756
- Testing
- Multiple Level Intertransverse Process Block, Single Level Intertransverse Process Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Head and Neck Cancer, Locally Advanced Head and Neck Carcinoma
Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer
This is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergoing chemoradiation.
- Trial name
- NCT05156060
- Testing
- Gabapentin, Ketamine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Natalie Lockney