Clinical trials: Cancer Pains
Back Pain, Chronic Pain
Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts
This study will demonstrate that functional improvement measures over a 6-month period for chronic low back patients under the care of Primary Care Provider (PCP), using a therapeutic plan formulated initially by the Pain…
- Conditions
- Back Pain, Chronic Pain, Pain, Intractable
- Trial name
- NCT02484937
- Testing
- Group 2 (PCP Treatment), Group 1 (PMS Treatment)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rush University Medical Center
Cancer
Dexamethasone for the Prophylaxis of Pain Flare Study
Radiation treatment is often recommended as a safe and quick treatment that gives most people good relief from bone pain within a couple of weeks.
- Trial name
- NCT00438828
- Testing
- dexamethasone
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Sunnybrook Health Sciences Centre
Nerve Block
Pectoral Nerve Block and Serratus Posterior Superior Intercostal Plane Block in Breast Cancer Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Pectoral Nerve Block (PECS II) and the Serratus Posterior Superior Intercostal Plane (SPSIP) Block in patients undergoing breast cancer…
- Trial name
- NCT07001657
- Testing
- SPSIP Block, PECS II Block
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Antalya Training and Research Hospital
Constipation, Opioid-Induced
Prevention of Opioid-induced Constipation in Patients With Advanced Cancer
More than 70% of patients with cancer in the palliative phase have pain that often requires treatment with opioids (morphine-like agents). Constipation occurs in 59% of patients treated with opioids.
- Trial name
- OMAMA (NCT05216328)
- Testing
- Macrogol Only Product in Oral Dose Form, Magnesium hydroxide 724mg
- Where
- 13 sites in Netherlands
- Volunteers
- 258 people
- Sponsor
- Amsterdam UMC, location VUmc
Cancer
Evaluating the Effectiveness of Art Therapy on Mood, Anxiety, and Pain Levels in Cancer Patients
Participants in this research study are asked to tell about their experience with art therapy. Participants in this research study are currently receiving chemotherapy treatment for cancer.
- Trial name
- NCT02659345
- Testing
- Emotions Thermometer, Art Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Case Comprehensive Cancer Center
Bowel Dysfunction, Constipation
Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Adults who are taking opioid therapy for persistent non-cancer pain and have resulting opioid-induced bowel dysfunction (OBD) will be randomized (1:1) to alvimopan or placebo.
- Trial name
- NCT00241722
- Testing
- Alvimopan
- Where
- 227 sites in United States, Australia and 15 more
- Volunteers
- 805 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Cancer, Metastasis
Effect of Samarium on the Relief of Pain Due to Vertebral Metastases
Cancer cells may spread from the primary site to the vertebrae resulting in their deformity. The standard treatment for this case is removal of the cancer deposits in the vertebra and filling the induced cavity with a cement like…
- Conditions
- Cancer, Metastasis, Pain
- Trial name
- NCT00374751
- Testing
- Samarium (153SM)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Peripheral Neuropathy, Antineoplastic Combined Chemotherapy Protocols
Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Chemotherapy-Induced Neuropathy
This study was designed to evaluate the safety and efficacy of Cesamet™ in controlling pain in subjects experiencing pain due to chemotherapy-induced neuropathic pain in patients with cancer.
- Trial name
- NCT00380965
- Testing
- Cesamet™ (nabilone)
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- NEMA Research, Inc.
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Cancer
Immediate-Release Oxycodone Capsules Study in Cancer Pain
The efficacy of dose titration of OxyNorm™(Oxycodone) immediate-release capsules versus morphine immediate-release tablets in the treatment of cancer pain.
- Trial name
- NCT01675622
- Testing
- Oxycodone, Morphine
- Volunteers
- 242 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Postoperative Pain Control, Opioid Consumption
Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery
The purpose of this study is to determine how a non-opioid pain control regimen, administered before and during surgery, will affect postoperative pain control and total opioid consumption in head and neck cancer participants…
- Trial name
- NCT04176419
- Testing
- Ketamine, Lidocaine, Acetaminophen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Case Comprehensive Cancer Center
Spinal Surgery
Understanding How Methadone Treatment During Surgery Affects Pain Levels and the Need for Pain Medications After Surgery
The researchers are doing this study to find out whether giving methadone during spinal surgery helps manage pain in the first 72 hours after surgery better than other standard pain medications.
- Trial name
- NCT05417100
- Testing
- Methadone
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Synergistic Effect of Ibuprofen and Hydromorphone for Postoperative Pain
Intravenous form of ibuprofen is recently approved by FDA and reports are rare on the co-administration with opioids. The investigators searched whether intravenous ibuprofen-hydromorphone combination is synergistic, additive, or…
- Trial name
- NCT02461056
- Testing
- Ibuprofen, Hydromorphone
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Cancer, Pain
Efficacy of Caffeine Injection as an Adjuvant to Opioid Therapy in Cancer Pain
Pain is a most common symptom and it has a high impact on quality of life in cancer patients. Many cancer patients have received opioid therapy, but also many of them have suffered from side effects of opioids.
- Trial name
- NCT00879775
- Testing
- Caffeine, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 41 people
- Sponsor
- Korea Research Foundation
Postoperative Pain
Postoperative Analgesic Effect of Subcostal TAPB for Laparoscopic Gastrectomy
This prospective, randomized, single blinded study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided subcostal transversus abdominis plane block in gastric cancer patients undergoing…
- Trial name
- NCT04138901
- Testing
- Ultrasound guided subcostal transversus abdominis plane block (TAPB), Ropivacaine 0.75% Injectable Solution, 21G 100 mm stimulator needle (Echoplex®, Vygon, Ecouen, France)
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Seoul National University Hospital
Hormone Therapy-induced Arthralgia, Phytotherapy
Evaluation of the Efficacy and Acceptability of a Phytotherapy Combining Devil's Claw, Blackcurrant and Meadowsweet for the Management of Aromatase Inhibitor-induced Arthralgia in Patients Treated for Localized Breast Cancer in the Adjuvant Setting
Adjuvant hormonotherapy is a cornerstone of treatment for localized hormone receptor-positive (HR+) breast cancer, accounting for approximately 80% of patients.
- Conditions
- Hormone Therapy-induced Arthralgia, Phytotherapy, Symptom Management, Adjuvant Treatment
- Trial name
- ERABLE (NCT07859319)
- Testing
- Phytotherapy Dietary Supplement (Harpagophytum, Meadowsweet, and Blackcurrant), Patient Experience Questionnaire
- Where
- 3 sites in France
- Volunteers
- 105 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer
A Pilot Trial to Assess the Impact of Acupuncture on Post-mastectomy Pain, Nausea, Anxiety and Ability to Cope
The purpose of the study is to compare the effect of acupuncture to the standard of care (control group) on pain, nausea, anxiety, ability to cope, costs and length of hospital stay in post-mastectomy patients at Abbott…
- Trial name
- NCT02122796
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Allina Health System
Cancer, Brachytherapy
Contribution of Hypnosis to Anxiety and Pain in Brachytherapy Patients
Formal hypnosis is a non-drug technique known to decrease anxiety and pain during the preoperative procedure. In brachytherapy, the practice of hypnosis has been shown to be feasible and beneficial for patients treated for…
- Trial name
- HYCUDES (NCT03755895)
- Testing
- formal hypnosis, Kalinox
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Institut de Cancérologie de Lorraine
Chronic Pelvic Pain Syndrome (CPPS), Radiation-Induced Disorder
Gene and Molecular Pathways of Ozone Treatment Response in Gynecological Tumor Patients With Chronic Pelvic Pain Secondary to Cancer Treatment
Gynecological cancers, including those affecting the ovaries, uterus, and cervix, represent a significant health burden for women.
- Conditions
- Chronic Pelvic Pain Syndrome (CPPS), Radiation-Induced Disorder, Radiotherapy Side Effects, Side Effect of Chemotherapy
- Trial name
- OzoGynEpigen (NCT06816095)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Bernardino Clavo, MD, PhD
Pancreatic Cancer, Pain
Evaluation of Injection Techniques in Celiac Plexus Neurolysis
1. To evaluate the efficacy of EUS-CPN in subjects who experience a sympathetic response during injection when compared with subjects who do not experience sympathetic response during injection.
- Trial name
- NCT02068677
- Testing
- Sympathetic response, no sympathetic response
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- AdventHealth
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