Clinical trials: Cancer Pains
Gastric Cancer, Postoperative Pain
Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy
This study is a single-center, prospective, randomized controlled trial designed to compare two established postoperative analgesic strategies in adult patients undergoing laparoscopic gastrectomy under general anesthesia.
- Trial name
- TAP-WELPASS (NCT07452471)
- Testing
- Ultrasound-guided Transversus Abdominis Plane (TAP) Block, Ropivacaine-Poloxamer 407 Hydrogel (Welpass®)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gyeong-Jo Byeon, MD, PhD
Breast Cancer, Aromatase Inhibitors
Assessment of Cryotherapy's Analgesic Impact in Anti-aromatase-induced Arthralgia
The first aim of this comparative, randomized, prospective, multicenter study is to evaluate the analgesic effect at 6 weeks of whole-body cryotherapy, compared to placebo cryotherapy, in patients suffering from arthralgia under…
- Trial name
- CRYOMATASE (NCT05315011)
- Testing
- Whole-body cryotherapy
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Montpellier
Chemotherapy-induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Use of PEA and Scutellaria in Synergy With Therapeutic Exercise in Chemotherapy-induced Peripheral Neuropathy (CIPN): a Clinical Trial
This study aims to find out if taking specific dietary supplements (PEA and Scutellaria) along with therapeutic exercise can help reduce nerve pain and damage caused by chemotherapy.
- Trial name
- NCT07352514
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Gynaecomastia, Prostate Cancer
Casodex - Nolvadex Combination
This study looks at the relationship in the dose of nolvadex and the incidence of gynaecomastia and also Prostate Specific Antigen (PSA) inhibition when co-administered with Casodex.
- Trial name
- NCT00637871
- Testing
- Casodex, Tamoxifen
- Sponsor
- AstraZeneca
Chronic Pain, Cancer
Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
This study seeks to explore the efficacy of immersive multimedia experiences as a practical adjunctive therapeutic intervention in the self-management of the chronic pain associated with cancer patients.
- Trial name
- NCT02995434
- Testing
- Virtual Reality Headset, 2D PC
- Where
- 3 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Bladder Cancer, Postoperative Pain
Comparing Rectus Sheath Catheter to Epidural Post Cystectomy
This is a prospective randomised controlled trial that will compare the outcomes of rectus sheath catheters to epidurals in patients who have undergone a cystectomy, via a lower midline abdominal incision for bladder cancer.
- Trial name
- NCT02572804
- Testing
- Epidural, Rectus Sheath Catheters
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Vancouver Coastal Health
Pediatric Cancer, Pain, Postoperative
Multimodal Analgesia in Major Abdominal Pediatric Cancer Surgeries
Surgical trauma initiates multiple physiological mechanisms that cause postoperative pain. Postoperative pain has nociceptive, inflammatory, and neuropathic components.Inadequate relief of postoperative pain leads to significant…
- Trial name
- NCT03580980
- Testing
- Paracetamol and ketamine, Caudal levobupivacaine, Morphine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Neurofibromatosis 1
Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas
This study will evaluate the effectiveness of skin cooling in increasing tolerability of four treatments in Neurofibromatosis Type 1 Cutaneous Neurofibromas.
- Trial name
- NCT06132165
- Testing
- Deoxycholic Acid, Polidocanol, 1064nm Nd:YAG laser
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Oropharyngeal Cancer, Dysphagia, Oropharyngeal
Liposomal Bupivacaine and Transoral Robotic Surgery
This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell…
- Conditions
- Oropharyngeal Cancer, Dysphagia, Oropharyngeal, Post Operative Pain, Transoral Robotic Surgery
- Trial name
- NCT05862792
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Geisinger Clinic
Break Through Pain, Cancer
A Clinical Trial With Intranasal Fentanyl in Cancer Patients With Breakthrough Pain
The aim of this clinical trial was to demonstrate the efficacy of a 400 μg dose strength of intranasal fentanyl spray (INFS, Instanyl®) and to evaluate the safety and to establish long term tolerability of treatment with INFS…
- Trial name
- NOSE-400 (NCT01429051)
- Testing
- Intranasal Fentanyl Spray (INFS)
- Where
- 11 sites in Hungary, Norway and 1 more
- Volunteers
- 46 people
- Sponsor
- Takeda
Chemotherapy Induced Peripheral Neuropathy (CIPN), Cancer
Effect of GMI With and Without NM on LE in Cancer Patients With CIPN
The goal of this interventional study is to learn if graded motor imagery with or without added neural mobilization can treat chemotherapy induced nerve related symptoms in lower limbs of cancer patients.
- Trial name
- CIPN (NCT07712302)
- Testing
- Graded Motor Imagery, Neural Mobilization
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Faisalabad
Breast Cancer
Surgical Intervention and Physiotherapy in Breast Cancer: Effects in Scapular Kinematics, Pain and Upper Limb Function
Our objective is to identify the possible changes of three-dimensional scapula movement during arm elevation in women after breast cancer surgery and subjected to a physical therapy intervention.
- Trial name
- NCT02604030
- Testing
- Upper limb function
- Where
- Brazil
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Aromatase Inhibitor, Musculoskeletal Symptoms
Auricular Point Acupressure to Self-Manage Chronic Pain or Aromatase Inhibitor Musculoskeletal Symptoms in Breast Cancer Survivors: Effectiveness and Scientific Underpinnings
Aromatase inhibitor therapy has become a standard adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive breast cancer.
- Conditions
- Aromatase Inhibitor, Musculoskeletal Symptoms, Postmenopausal Breast Cancer Survivors
- Trial name
- NCT03697200
- Testing
- APA, Education control
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Johns Hopkins University
Cancer
Safety and Effectiveness of Transdermal Buprenorphine in Cancer Pain
Buprenorphine transdermal patch is newly available in Taiwan in June 2017, the trade name is Transtec, and the available dosages are 35 μg/h and 52.5 μg/h.
- Trial name
- SOOTHE (NCT04315831)
- Testing
- Transdermal Buprenorphine
- Where
- Taiwan
- Volunteers
- 83 people
- Sponsor
- Taiwan Mundipharma Pharmaceuticals Ltd.
Periapical Diseases, Radicular Cyst
PRF Membrane and Recovery After Periapical Surgery: A 3D Imaging Study
The goal of this clinical trial is to determine whether a PRF (platelet-rich fibrin) membrane helps improve recovery after periapical surgery in adults.
- Conditions
- Periapical Diseases, Radicular Cyst, Granuloma, Postoperative Complications
- Trial name
- NCT06739200
- Testing
- Platelet-Rich Fibrin (PRF) Membrane
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gynaecologic Cancer
Impact of Peritoneal Gas Drain on Postoperative Pain for Gynaecological Cancer Patients With Minimally Invasive Surgery
This is a phase III, monocenter and randomized study, which evaluates the effectiveness of peritoneal gas drainage on postoperative pain in laparoscopic or robotic laparoscopic gynaecological surgery.
- Trial name
- DRAIN-EXSU (NCT04974125)
- Testing
- Drain, Manual exsufflation
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Oscar Lambret
Cancer, Cancer Pain
Antalgic Effects of Well-being Treatments in Cancer Care
observational , Monocentric, study to assess antalgic effects of well-being treatment in cancer care.
- Trial name
- Well Being (NCT05493150)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier de Valence
Breast Cancer, Joint Pain
Glucosamine and Chondroitin for Aromatase Inhibitor Induced Joint Symptoms in Women With Breast Cancer
Investigators are hoping to learn if glucosamine with chondroitin can help relieve joint pain/stiffness associated with aromatase inhibitors.
- Trial name
- NCT00691678
- Testing
- Chondroitin, Glucosamine
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Dawn L. Hershman
Actinic Keratosis
Effect of IDEA-070 on Pain and Inflammation Induced by PDT
Primary objectives: effect of IDEA-070 compared to placebo on pain and inflammation induced by PDT. The primary objective is to detect a statistically significant difference of pain and inflammation induced by PDT in test areas…
- Trial name
- NCT00269074
- Testing
- IDEA-070
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- IDEA AG
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Intrathecal Ziconotide in Chemotherapy Induced Peripheral Neuropathy
The purpose of this observational, data collection, research is to evaluate if ziconotide, a commercially approved medication given by a FDA cleared intrathecal pump, for chronic pain is effective in the treatment of…
- Trial name
- NCT07499882
- Testing
- Ziconotide
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Christian Hospital Northeast Northwest
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