Clinical trials: Cancer Pains
Non Small Cell Lung Cancer, Lung Cancer Stage 1
Exparel and Marcaine for Pain Management in Thoracoscopic Lobectomy Patients
The purpose of this study is to assess pain management after elective thoracoscopic lobectomy. The study will compare two local anesthetics that are given intra-operatively during lobectomy to see which one helps in better pain…
- Trial name
- BEMP (NCT03682224)
- Testing
- Liposomal Bupivacaine, Bupivacaine-Epinephrine
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Southern Illinois University
Chronic Pain
Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain
Aim of this project is to customize the choice of the strong opioid in the treatment of cancer chronic pain through the identification of patient clinical history and pain characteristics, moreover in the analysis the…
- Trial name
- NCT00916890
- Testing
- Morphine, Oxycodone, Fentanyl
- Where
- 6 sites in Italy
- Volunteers
- 320 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Acquired Immunodeficiency Syndrome, Burning Mouth Syndrome
Thalidomide to Treat Oral Lesions in HIV-Infected Patients
This study will test the effectiveness of topical thalidomide in healing mouth sores in HIV infected patients. Oral (PO) thalidomide heals these sores at a dose of 200 mg per day.
- Conditions
- Acquired Immunodeficiency Syndrome, Burning Mouth Syndrome, HIV Infection
- Trial name
- NCT00001524
- Testing
- Thalidomide
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Intraoperative Complication, Malignant Female Reproductive System Neoplasm
Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
This randomized clinical trial studies epidural anesthesia within an enhanced recovery pathway (ERP) in reducing pain in patients undergoing gynecologic surgery.
- Conditions
- Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
- Trial name
- NCT02423876
- Testing
- Epidural analgesia, Intraoperative Complication Management and Prevention, Pain Therapy
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Wisconsin, Madison
Oral Mucositis
Smartphone Pain App for Assessing Oral Mucositis Pain in Patients
This research is being done to evaluate whether or not the Oral Mucositis (OM) Pain App (a smartphone application) is a feasible and valid tool to assess pain from radiation sores (also referred to as "mucositis") when treating…
- Trial name
- NCT02727062
- Testing
- OM Pain App, Accelerometer
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Stuart Wong
Esophageal Cancer
Postoperative Pain Management After Minimally Invasive Esophagectomy
Esophagectomy is a major surgical procedure often associated with significant morbidity and mortality and significant level of postoperative pain.
- Trial name
- MIEPVBEA (NCT02042313)
- Testing
- continuous epidural infusion, combined paravertebral infusion and single shot of TAP block
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- Sun Yat-sen University
Chronic Nonmalignant Pain, Pain, Intractable
Post-market, Randomized, Controlled, Prospective Study Evaluating Intrathecal Pain Medication (IT) Versus Conventional Medical Management (CMM) in the Non-cancer, Refractory, Chronic Pain Population
This study is being conducted to compare intrathecal morphine using the commercially available intrathecal drug delivery systems (IDDS), and conventional medical management (CMM) in subjects with non-cancer, refractory chronic…
- Conditions
- Chronic Nonmalignant Pain, Pain, Intractable, Pain, Chronic
- Trial name
- Prosper-001 (NCT04096391)
- Testing
- Flowonix Prometra® II Programmable Infusion System, Pain Medicine
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Evolve Restorative Center
Nausea, Vomiting
Effect of a Symptom Diary on Symptom Care and Symptom Burden in Patients Treated With Chemotherapy: a Before-and-after-study
This study investigates whether the implementation of a symptom diary for reporting and communicating chemotherapy-related symptoms improves symptom care and decreases symptom burden in adult patients treated with chemotherapy.
- Conditions
- Nausea, Vomiting, Pain, Anorexia
- Trial name
- NCT02050490
- Where
- Belgium
- Volunteers
- 236 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Knee Osteoarthritis
Platelet-rich Plasma and Synovial Cytokines in Knee Osteoarthritis
A prospective study was performed on 90 patients were included and categorized into mild (30 cases, moderate (30 cases) and severe (30 cases) knee OA. Three intra-articular (I.A) injections of PRP, 2 weeks a part, were received.
- Trial name
- NCT04754685
- Testing
- Intra-articular injection of platelet-rich plasma
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Valley University
Cancer, Cancer Pain
Virtual Reality for Cancer Pain Management
The purpose of this research project is to evaluate the impact of virtual reality therapy on mitigating cancer pain in hospitalized patients with cancer and compare this impact to that of 2-dimensional guided imagery distraction…
- Trial name
- NCT04572074
- Testing
- Guided imagery, Virtual reality
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Medstar Health Research Institute
Opioid-induced Constipation
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
This study will evaluate the safety and efficacy of Tegaserod in opioid-induced constipation in patients with non-cancer pain. Patients who enter this study PRIOR to the core study (CHTF919N2201) interim analysis receive the…
- Trial name
- NCT00414024
- Testing
- Tegaserod
- Where
- 6 sites in United States, China and 4 more
- Volunteers
- 11 people
- Sponsor
- Novartis
Female Breast Cancer
Exercise Program on Pain, Physical Function, and Quality of Life in Breast Cancer Survivors
The purpose of this project is to develop a randomized clinical trial to determine the efficacy of a supervised exercise program on pain, physical function and quality of life in female breast cancer survivors
- Trial name
- IO/2024 (NCT06618690)
- Testing
- Exercise program
- Where
- Spain
- Volunteers
- 325 people
- Sponsor
- Universidad de Burgos
Oral Mucosa Discomfort, Pediatric Cancer
Music Therapy for Oral Mucositis Pain in Pediatric Patients
This mixed-methods pilot study will examine the effect of music therapy on oral mucositis pain in pediatric oncology patients. Oral mucositis, characterized by painful ulcerative lesions in the mouth, is a common side effect of…
- Conditions
- Oral Mucosa Discomfort, Pediatric Cancer, Mucositis Oral
- Trial name
- NCT07653360
- Testing
- Semi-Structured Interviews
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Choroidal Melanoma, Melanoma
Pain Relief - Tramadol Versus Ibuprofen
The purpose of this study is to assess post operative pain following the insertion of radioactive plaque for choroidal melanoma in patients after receiving either ibuprofen or tramadol.
- Conditions
- Choroidal Melanoma, Melanoma, Eye Neoplasms
- Trial name
- NCT00111046
- Testing
- Ibuprofen, Tramadol
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Liverpool University Hospital
Kidney Cancer, Post-surgical Pain
ESP Block for Laparoscopic Nephrectomy Surgeries
Nephrectomy (kidney removal) is one of the most common surgical procedures in urologic practice. Recent advances in laparoscopic (keyhole) procedures have resulted in a significant decrease in open nephrectomies.
- Trial name
- ESPB (NCT04085237)
- Testing
- Ropivacaine injection
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McMaster University
Pain Score, Morphine Consumption
Comparison of Efficacy of Regional Blocks in Breast Surgeries.
After Standardized anesthetic induction patients were randomly given regional blocks. Group A recieved erecter spinae plane block \& group B recieved combined serratous anterior and pecto-intercoatal facial plane block.
- Trial name
- NCT07362472
- Testing
- Regional nerve blocks
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Breast Cancer Females
Auricular Acupressure for Perioperative Anxiety and Pain in Therapeutic Breast Surgery (ROSA)
This randomized, controlled, single-center trial investigates the effects of auricular acupressure, administered according to the National Acupuncture Detoxification Association (NADA) protocol, on perioperative anxiety and pain…
- Trial name
- ROSA (NCT07423039)
- Testing
- Auricular Acupressure NADA
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Breast Cancer
Behavioral Pain Intervention for Older Cancer Patients
This randomized controlled trial examines a 1-session, telehealth pain coping skills training (PCST) protocol with five 15-minute maintenance calls (Brief PCST-Community) adapted for women with breast cancer in medically…
- Trial name
- NCT07300995
- Testing
- Pain Coping Skills Training (PCST)
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Weill Medical College of Cornell University
Pain, Cancer
Long-term Safety Study of Sublingual Fentanyl Tablets in Cancer Patients
The purpose of this study is to evaluate the long-term safety and effectiveness of EN3267 in treating breakthrough pain episodes in opioid cancer patients who are using stable doses of opioid medication.
- Trial name
- NCT00263575
- Testing
- EN3267
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Cancer, Depression
Pharmacogenomic Testing to Personalize Supportive Oncology
The purpose of this study is to evaluate pharmacogenomics (PGx) guided drug prescribing for pain and depression in patients with cancer.
- Conditions
- Cancer, Depression, Pain
- Trial name
- NCT04500301
- Testing
- Preemptive Pharmacogenomic Testing
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Wake Forest University Health Sciences
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