Clinical trials: Cancer Pains
Phantom Limb Pain, Residual Limbs
Focused Ultrasound Treatment of Stump Neuromas for the Relief of Chronic Post-Amputation Neuropathic Pain
AIM: To provide initial information on the efficacy (pain reduction) and safety of focused ultrasound surgery for the ablation of stump neuromas in amputees with chronic neuropathic pain.
- Conditions
- Phantom Limb Pain, Residual Limbs, Amputation
- Trial name
- NCT03255395
- Testing
- Magnetic resonance-guided focused ultrasound
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Rambam Health Care Campus
Post-mastectomy Pain Syndrome, Chronic Post-surgical Pain
Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Breast tissue and the areas surrounding the breast contain many small to medium-sized nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
- Trial name
- PLAN (NCT02240199)
- Testing
- Intraoperative Intravenous Lidocaine Infusion, Perioperative Pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Cancer Pain, Palliative Care
e-Natureza Blue Care: Nature-based Virtual Reality and Pain Perception
This randomized clinical trial aims to evaluate the effectiveness of immersive nature-based virtual reality in managing chronic pain among oncology patients.
- Trial name
- e-NatBlue (NCT07053228)
- Testing
- Nature-based virtual reality, Standard Pain Management
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Hospital Israelita Albert Einstein
Analgesia, Surgery
Postoperative Pain, Why Still in Hospital and DAOH Following TORS for SCCUP & OSAS
This protocol investigates the effect of a high dose dexamethasone regimen in the treatment of postoperative pain following Transoral Robotic Surgery (TORS). The protocol consists of three substudies. 1.
- Conditions
- Analgesia, Surgery, Cancer of Head and Neck, Oropharyngeal Cancer
- Trial name
- NCT04189107
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Grade III and IV Hemorrhoids
Haemorrhoidectomy With vs Without Lateral Internal Sphincterotomy
Hemorrhoids are a common anorectal condition that often require surgical treatment in advanced stages. Open hemorrhoidectomy is effective but is frequently associated with significant postoperative pain and early bleeding.
- Trial name
- NCT07360912
- Testing
- Hemorrhoidectomy With LIS, Conventional Hemorrhoidectomy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
Metastases
A Phase I/II Dose Escalation Study Using Extracranial Stereotactic Radiosurgery to Control Pain
This study will evaluate pain control and quality of life in patients with paraspinal metastases, who have receive previous radiation therapy to these lesions, using single dose stereotactic radiotherapy.
- Trial name
- NCT00802659
- Testing
- Stereotactic radiotherapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Washington University School of Medicine
Adenoma, Pain
Water Method in Low-body Mass Index (BMI) Female Patients With Unsedated Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Trial name
- NCT01546259
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
Breast Cancer
Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
Perform a comparison of effective pain relief duration between liposomal bupivacaine and dexmedetomidine when added to bupivacaine in a block for mastectomy for cancer surgery.
- Trial name
- NCT06252662
- Testing
- Dexmedetomidine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy
Pain, Psychological, and Endocannabinoid Responses to Yoga in Breast Cancer Survivors With Chemotherapy-induced Neuropathic Pain
This study evaluates the acute effect of aerobic exercise and yoga on pain, plasma levels of endocannabinoids, and mood (i.e., mood disturbance and anxiety). Participants will complete three separate sessions on different days.
- Conditions
- Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Neuropathic Pain
- Trial name
- NCT04075097
- Testing
- Aerobic exercise, Iyengar yoga
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison
Pain
Fentanyl for Breakthrough Pain in the Emergency Department
The goal of this clinical research study is to learn if fentanyl nasal spray can help decrease pain related to cancer when used with other drugs for pain.
- Trial name
- NCT01812759
- Testing
- Fentanyl Nasal Spray, Hydromorphone PCA
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Knee Osteoarthritis
Wearable LITUS Device for Osteoarthritis of the Knee: a Randomized Double-Blind Placebo-Controlled Trial
The purpose of this study is to measure the effectiveness of a wearable therapeutic ultrasound device in patients with stage I and stage II knee osteoarthritis.
- Trial name
- NCT02083861
- Testing
- Sam Ultrasonic Diathermy Device
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- ZetrOZ, Inc.
Pancreatic Cancer, Visceral Pain
Efficacy Of Pregabalin In The Treatment Of Pancreatic Cancer Pain. A Randomized Controlled Double-Blind, Parallel Group Study
This is a randomized, double blind controlled, parallel arms trial, aimed to assess the efficacy of pregabalin on pancreatic cancer induced abdominal pain.
- Trial name
- PANPAIN/1 (NCT01768988)
- Testing
- Pregabalin
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Parc de Salut Mar
Cancer, Breakthrough Pain
Efficacy/Safety Study of ACTIQ® for Opioid-Tolerant Children and Adolescents With Breakthrough Pain (BTP)
The primary objective of the study is to evaluate the efficacy of ACTIQ treatment for the management of breakthrough pain (BTP) compared to placebo treatment in children with cancer and non-cancer pain who are receiving…
- Trial name
- NCT00236041
- Testing
- ACTIQ®
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 38 people
- Sponsor
- Cephalon
Thoracic Neoplasm, Chronic Pain Post-Procedural
Preoperative Paravertebral Block in Cancer Surgery of the Lung
The investigators aim to determine whether ultrasound-guided preemptive paravertebral blockade (PVB) local anaesthetic (pre-PVB LA), administered in addition to the post-operative PVB (post-PVB) local anaesthetic (LA) infusion…
- Conditions
- Thoracic Neoplasm, Chronic Pain Post-Procedural, Acute Post-thoracotomy Pain, Anesthesia, Local
- Trial name
- ParaSOL (NCT04209868)
- Testing
- Levo-Bupivacaine Hydrochloride (HCl) 0.5 % in 20mL Injection, 0.9% Sodium Chloride 20mL Injection
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Breast Cancer, Breast Pain
Calming Alternatives Learned During MRI-Guided Breast Biopsy
The proposed randomized study evaluates whether a controlled breathing intervention could be efficacious for reducing pain in the MRI-guided breast biopsy setting.
- Conditions
- Breast Cancer, Breast Pain, Pain, Acute, Anxiety
- Trial name
- CALM (NCT03877146)
- Testing
- Controlled Breathing Intervention
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Duke University
Cancer Pain
The Effect of Patient-Controlled TEAS vs Sham TEAS for Improve Quality of Life in Patients With Cancer Pain
The conduct of a pilot trial is of great significance as a means of assessing the feasibility and harmonization of the research and is a very necessary precursor to the better conduct of formal trials.
- Trial name
- NCT06188286
- Testing
- Transcutaneous electrical acupoint stimulation
- Volunteers
- 94 people
- Sponsor
- Yi Liang
Breast Cancer, Arthralgia
Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer
Early stage hormone receptor positive breast cancer is typically treated with adjuvant endocrine therapy in order to decrease risk of breast cancer recurrence and to improve overall survival from the disease.
- Conditions
- Breast Cancer, Arthralgia, Obesity
- Trial name
- LOGRIBMET (NCT01896050)
- Testing
- anastrozole, letrozole, exemestane, Tamoxifen
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Michigan Rogel Cancer Center
Breast Cancer Female
Pain and Functional Recovery After Mastectomy and IBR by Implant: Prepectoral Versus Subpectoral Technique
This is a prospective, single-center, non-randomized study of immediate breast reconstruction (IBR) using a pre- or retro-pectoral technique in patients with breast cancer who have undergone total mastectomy.
- Trial name
- DREAM-RMI (NCT05527769)
- Testing
- mastectomy + immediate breast reconstruction
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Institut Cancerologie de l'Ouest
Cancer and Non-cancer Hospice Patients
Virtual Reality for Improving Symptoms in Palliative Care
The objective of this study is to determine whether VR can ameliorate symptoms for palliative care patients within a hospice setting.
- Trial name
- VRPC (NCT05197894)
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Enhanced Recovery After Surgery
ERAS on Postoperative Recovery After Laparoscopic Distal Gastrectomy
This prospective, randomized, open-labeled study is designed to evaluate the impact of enhanced recovery after surgery (ERAS) protocol on postoperative quality of recovery in patients undergoing laparoscopic distal gastrectomy.
- Trial name
- NCT05649319
- Testing
- ERAS protocol
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Seoul National University Hospital
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