Clinical trials: Cancer Pains
Breast Cancer, Recurrent Breast Cancer
Acupuncture in Treating Women With Stage I, Stage II, or Stage III Breast Cancer With Aromatase Inhibitor-Related Joint Pain
RATIONALE: Acupuncture may help relieve moderate or severe joint pain caused by aromatase inhibitors. PURPOSE: This randomized phase II trial is studying acupuncture in treating women with stage I, stage II, or stage III breast…
- Conditions
- Breast Cancer, Recurrent Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT01013337
- Testing
- acupuncture therapy
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Breast Cancer, Postoperative Recovery
ERAS Protocols in Breast Conserving Surgery
Enhanced Recovery After Surgery (ERAS) protocols have been of increasing interest in the surgical community for decades. The emphasis has been development of protocols to maximize pain control post-operatively without the use of…
- Trial name
- ERAS (NCT06938581)
- Testing
- ERAS Protocol, Standard Perioperative Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Nebraska
Cancer, Pain
Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain
The purpose of this study is to determine whether oral methadone plus acetaminophen can substitute morphine in the treatment of cancer pain.
- Conditions
- Cancer, Pain, Palliative Care
- Trial name
- NCT00525967
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Faculdade de Medicina do ABC
Multiple Myeloma
Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma
Multiple myeloma is a plasma cell neoplasm that can cause painful bone lesions. The main treatment for these lesions and pain control is radiotherapy, usually in daily fractions.
- Trial name
- NCT05996367
- Testing
- Single-dose involved-site radiotherapy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Neuropathic Pain
Neuropathic Pain in Patients With Cancer
The purpose of this study is to collect beginning information on whether intravenous (IV) administration of KRN5500 is safe and effective for treatment of neuropathic pain in patients with cancer.
- Trial name
- NCT00474916
- Testing
- KRN5500
- Where
- 12 sites in United States, Puerto Rico
- Volunteers
- 19 people
- Sponsor
- DARA Therapeutics
The Patients With Gastric Cancer Who Are Scheduled to Receive Laparoscopy Assisted Gastrectomy
Comparison of Analgesic Efficacy and Occurrence of Emesis Among Different Background Infusion and Bolus Administration Regimens of Fentanyl Based Intravenous Patient-controlled Analgesia in Patients After Laparoscopic Assisted Gastrectomy - a Randomized Blind Study -
Fentanyl based intravenous patient controlled analgesia(PCA)is popular method for postoperative pain control, but information regarding optimal dose of fentanyl in IV PCA is currently lacking.
- Trial name
- NCT01863355
- Testing
- B0 group: bolus 0.6mcg/kg without background infusion, BL group: bolus 0.4mcg/kg with background infusion rate 0.2mcg/kg/hr, BH group: bolus 0.2mcg/kg with background infusion rate 0.4mcg/kg/hr
- Where
- South Korea
- Volunteers
- 225 people
- Sponsor
- Yonsei University
Erector Spinae Plane Block
The Effects of Erector Spinae Plane Block on Pain Scores in Unilateral Breast Cancer Surgery
The high incidence of breast cancer is increasing the need for oncologic breast surgery. The optimal acute postoperative pain management after breast surgery is not yet clear.
- Trial name
- NCT07134933
- Testing
- ESP (erector spinae plane)block
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Inonu University
Pain, Prostate Cancer
Epidural Hydromorphone Compared With Hydromorphone Infusion in Treating Patients With Prostate Cancer Undergoing Radical Prostatectomy
RATIONALE: Giving hydromorphone in different ways may relieve the pain associated with cancer surgery. PURPOSE: Randomized double-blinded phase III trial to compare the effectiveness of epidural hydromorphone with hydromorphone…
- Trial name
- NCT00003115
- Testing
- hydromorphone hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Roswell Park Cancer Institute
Fibromyalgia, PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Evaluation of Fibromyalgia Frequency and Pain Parameters in Women With Polycystic Ovary Syndrome
The primary objective was to determine the prevalence of fibromyalgia in women with PCOS and to examine the relationship between fibromyalgia and psychological status (depression and anxiety).
- Trial name
- NCT07189247
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Breast Cancer, Pain
The Effect of Music on Pain, Anxiety and Satisfaction During Mammography
This study was planned to determine the effect of music listened to during mammography screening on pain, anxiety and satisfaction.
- Conditions
- Breast Cancer, Pain, Anxiety
- Trial name
- NCT06222684
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cervical Cancer, Cervical Dysplasia
Coughing at Time of Cervical Biopsy
To investigate the effect of coughing as an intervention to reduce pain in colposcopy guided biopsy.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Colposcopy, Pain Sensation
- Trial name
- NCT06149598
- Testing
- Coughing at the time of biopsy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Zydolab - Institute of Cytology and Immune Cytochemistry
Breast Neoplasm Female, Analgesics
U/S Guided Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block vs Type 2 Pectoral Nerve Block
The aim of this study is to compare between U/S Guided Rhomboid Intercostal Block Combined with Sub-Serratus Plane Block vs type 2 Pectoral Nerve Block in Analgesia for Breast Cancer Surgery by measuring intraoperative…
- Trial name
- NCT06274814
- Testing
- U/S guided Type 2 Pectoral Nerve Block, U/S guided RIB combined with the sub-serratus plane block (RISS)
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- National Cancer Institute, Egypt
Stomatitis
Morphine Mouthwash for Management of Oral Mucositis in Patients With Head and Neck Cancer
Oral mucositis is a debilitating side effects of cancer treatment for which there is not much successful treatments at yet. The investigators are going to evaluate the effectiveness of topical morphine compared with a routine…
- Trial name
- NCT01837446
- Testing
- 2% morphine solution, Magnesium aluminum hydroxide, 2% viscous lidocaine
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Isfahan University of Medical Sciences
Hematological Malignancies
Impact of Child Positioning on Pain During a Lumbar Puncture
This protocol is a pilot study on standard care. The main goal is to assess the impact of positioning on lumbar puncture process especially on pain sensitivity in children.
- Trial name
- PHIPA-PEPL (NCT02834156)
- Testing
- LP in a seated position then LP in a lying position, LP in a lying position then LP in a seated position
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Malignancy, Pain Management
Endoscopic Ultrasound Guided Coeliac Plexus Neurolysis for Cancer Pain
Many cancer patients suffer from intractable pain and which is often suboptimally controlled by even strong opioid analgesics. Coeliac plexus neurolysis (CPN) is procedure which intended to permanently destroy the nociceptive…
- Trial name
- NCT04801082
- Testing
- Alcohol injection, Radiofrequency Ablation
- Where
- Hong Kong
- Volunteers
- 54 people
- Sponsor
- The University of Hong Kong
Constipation, Pain
Efficacy of Oxycodone/Naloxone(OXN), Versus Oxycodone (OXY), for the Reduction of Intensity of Opioid-induced Constipation in Pain Patients
The primary objective of this trial is to study the efficacy of oxycodone/naloxone prolonged release tablets (OXN PR), compared to oxycodone prolonged release tablets (Oxy PR), for the reduction of the intensity of opioid-induced…
- Trial name
- OXN3505 (NCT01014559)
- Testing
- Oxycodone Naloxone, Oxycodone PR Tablets
- Where
- France
- Volunteers
- 225 people
- Sponsor
- Mundipharma SAS
Peripheral Neuropathic Pain
Vitamin D Supplementation in Breast Cancer Patients
It is a randomized clinical trial aimed at exploring the neuroprotective effect of vitamin D3 (Cholecalciferol) supplementation in conjunction with paclitaxel-based chemotherapy among breast cancer patients with vitamin D…
- Trial name
- NCT06596122
- Testing
- Vitamin D (Cholecalciferol )
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Abdelrahman Mahmoud
Neurosurgery, Brain Cancer
DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial)
Post-craniotomy pain is common and often undertreated. Inadequate analgesia can lead to patient discomfort and higher opioid consumption, which may result in respiratory depression, sedation risks and impaired neurological…
- Conditions
- Neurosurgery, Brain Cancer, Meningioma
- Trial name
- DEX-NEURO (NCT07398066)
- Testing
- Dexmedetomidine, Normal Saline (0.9% NaCl)
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Cancer, Bone Metastases
Magnetic Resonance Guided High Intensity Focused Ultrasound (MRgHIFU) for Pain Palliation of Bone Metastases
The primary objective of this study is to determine whether intra- and post-procedural MR changes are indicative of reduction in pain symptom scores.
- Trial name
- HIFU-Bone (NCT03479151)
- Testing
- Magnetic Resonance Image-guided High Intensity Focused Ultrasound (MR-HIFU)
- Where
- United Kingdom
- Sponsor
- Institute of Cancer Research, United Kingdom
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