Clinical trials: Cancer Pains
Myocardial Infarction, Unstable Angina
CORonary Diet Intervention With Olive Oil and Cardiovascular PREVention
The purpose of this study is to compare the effects of the consumption of two different dietary patterns (low fat versus Mediterranean Diet) on the incidence of cardiovascular events of persons with coronary disease.
- Conditions
- Myocardial Infarction, Unstable Angina, Malignancy, Cognitive Decline
- Trial name
- CORDIOPREV (NCT00924937)
- Testing
- Mediterranean Diet, Low Fat Diet
- Where
- Spain
- Volunteers
- 1,002 people
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Breast Cancer, Pain Management
Nonpharmacological Management of Pain and Fear During Hormone Injection in Breast Cancer Patients
This randomized controlled study will compare the effects of the ShotBlocker device and the Helfer Skin Tap Technique on pain and fear during intramuscular hormone injections in premenopausal and postmenopausal breast cancer…
- Conditions
- Breast Cancer, Pain Management, Fear, Injection Fear
- Trial name
- NCT07406165
- Testing
- ShotBlocker device, This involves rhythmic, gentle tapping with the fingertips on the skin surrounding the gluteal injection site.
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Inonu University
Malignancy-induced Pelvic Pain
CT-guided Pudendal Nerve Cryoneurolysis for Palliation of Malignancy-induced Pelvic Pain
We want to study if a new treatment called "CT-guided bilateral pudendal nerve cryoneurolysis" can help people with severe and long-lasting pain in the pelvic area caused by cancer.
- Trial name
- NCT06110065
- Testing
- CT-guided Pudendal Nerve Cryoneurolysis, Percutaneous image-guided cryoneurolysis
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Arizona
Oral Cancer, Postoperative Pain Management
Effect of Dezocine Versus Nalbuphine Combined With Sufentanil on Postoperative Analgesia, Complications, and Free Flap Survival in Patients Undergoing Oral Cancer Radical Surgery: A Randomized Controlled Clinical Trial.
Background: Oral cancer radical surgery often requires free flap reconstruction. Postoperative pain is severe, and traditional opioids like sufentanil have side effects and may adversely affect tumor biology.
- Conditions
- Oral Cancer, Postoperative Pain Management, Free Tissue Flaps, Mouth Neoplasms
- Trial name
- NCT07401641
- Testing
- Dezocine and Sufentanil combination, Nalbuphine and Sufentanil combination
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cancer Pain, Real-world Study
Real World Study of Oxycodone Sustained-release Tablets for Patients With Moderate to Severe Cancer Pain
The goal of this real world study is to observe the efficacy and safety of Oxycodone Hydrochloride Sustained-release Tablets in the treatment of moderate to severe cancer pain participants in real clinical practice.
- Conditions
- Cancer Pain, Real-world Study, Oxycodone
- Trial name
- NCT05962294
- Where
- China
- Volunteers
- 916 people
- Sponsor
- Henan Cancer Hospital
Cancer Pain
Endovascular Denervation in Patients With Cancer Pain
Endovascular arterial denervation (ED) is a minimally invasive technique which could reduce the occurrence of injury of visceral tissue or organs.
- Trial name
- NCT03431922
- Testing
- endovascular denervation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhongda Hospital
Lung Cancer
Bupivacaine Liposome Serrate Anterior Plane Block vs Traditional Thoracic Paravertebral Block
In this study, patients will receive bupivacaine liposome serratus anterior plane block or ropivacaine paraspinal block to manage postoperative pain.
- Trial name
- NCT06135545
- Testing
- Bupivacaine Liposome SAPB, Traditional TPVB
- Where
- China
- Sponsor
- Shiyou Wei
Breast Cancer
Chronic Post Breast Surgery Pain
The purpose of this study is to learn if paravertebral block (PVB) will reduce chronic pain after surgery. Our hypothesis is that chronic pain from breast surgery as a consequence of central sensitization can be prevented by…
- Trial name
- NCT00847067
- Testing
- Paravertebral block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Neoplasm Metastases
Oral Piroxicam Versus Buccal Fentanyl in Breakthrough Pain
100 patients with Breakthrough pain will be allocated to receive either oral prioxicam (OP) (n=50) or sublingual fentanyl (SLF) (n=50) .
- Trial name
- NCT02382653
- Testing
- oral perixicam
- Volunteers
- 100 people
- Sponsor
- Tanta University
Pain, Neuropathic, Epilepsy
Cancer in Patients With Gabapentin (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in AERS or in the…
- Conditions
- Pain, Neuropathic, Epilepsy, Renal Pelvis Cancer, Pancreatic Cancer
- Trial name
- NCT01236053
- Testing
- Gabapentin prescriptions
- Volunteers
- 2,323,608 people
- Sponsor
- GlaxoSmithKline
Grade III and IV Hemorrhoids
Haemorrhoidectomy With vs Without Lateral Internal Sphincterotomy
Hemorrhoids are a common anorectal condition that often require surgical treatment in advanced stages. Open hemorrhoidectomy is effective but is frequently associated with significant postoperative pain and early bleeding.
- Trial name
- NCT07360912
- Testing
- Hemorrhoidectomy With LIS, Conventional Hemorrhoidectomy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
Stage II and III Breast Cancer
Melatonin as Adjuvant Therapy in Breast Cancer Patients
The study evaluate the effect of melatonin in improving quality of life and reducing post operative pain and chemotherapy-induced toxicity in breast cancer patients.
- Trial name
- MIQOL-B (NCT01557478)
- Testing
- Melatonin
- Where
- 2 sites in Thailand
- Volunteers
- 166 people
- Sponsor
- Khon Kaen University
Metastatic Solid Tumors of Metastatic Disease
Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain
The purpose of the study is to compare the outcome of patients who receive standard treatment versus those who receive preventative radiation and then standard treatment.
- Trial name
- NCT03523351
- Testing
- Radiation Therapy, Systemic Therapy
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Dietary and Exercise Interventions in Reducing Side Effects in Patients With Stage I-IIIa Breast Cancer Receiving Aromatase Inhibitors
This phase I/II trial studies how well dietary and exercise interventions work in reducing side effects in patients with stage I-IIIa breast cancer taking aromatase inhibitors.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT03953157
- Testing
- Dietary Intervention, Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Cancer Patient Confined in the Bed
Osteopathy Treatment for Cancer Pain Related to the Confinement to Bed
Staying confined in the bed is frequent at the end of life. The cancer patients can also experiment this situation, and consequences are painful, with pain increasing with the time.
- Trial name
- OSTEO (NCT03440957)
- Testing
- Osteopathic treatment
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Hospices Civils de Lyon
Colorectal Neoplasms
Acupuncture to Reduce Symptoms of Advanced Colorectal Cancer
This study investigates the effect of acupuncture in reducing symptom distress in adults with advanced colon cancer.
- Trial name
- NCT00034034
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Nurse's Role, Pain Management
Effect of Virtual Reality on Pain and Anxiety During Pap Smear Testing
This randomized controlled pretest-posttest experimental study aims to evaluate the effect of virtual reality (VR) on pain and anxiety levels experienced during Pap smear sampling.
- Conditions
- Nurse's Role, Pain Management, Cervical Cancer Screening, Anxiety
- Trial name
- NCT07462039
- Testing
- Virtual Reality
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Pain, Head and Neck Cancer
Pain Related to Head and Neck Cancer (HNC); Implementation and Evaluation of Self-care Measure Due to the Same Illness
The purpose of this study is to evaluate the effect of individual education and individual self-care measures on pain intensity, perceived health, mood and sleep during and after treatment with radiotherapy for head and neck…
- Trial name
- HNC (NCT03089736)
- Testing
- Education, Self Care, Treatment as usual (TAU)
- Volunteers
- 62 people
- Sponsor
- Linkoeping University
Cancer, Hepatic, Cancer, Esophagus
Expectation, Pain Outcomes, and Pain Medication Following Oncology Abdominal Surgery: A Cohort Study
This study includes participants undergoing major hepatic surgery, surgery in the esophagus or stomach, or major surgery on the pancreas performed at Copenhagen University Hospital, Rigshospitalet.
- Conditions
- Cancer, Hepatic, Cancer, Esophagus, Cancer, Pancreas
- Trial name
- NCT07176052
- Testing
- cancer surgery
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Lymphoblastic Leukemia ALL
Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy.
The goal of this clinical trial is to learn if a home-based program that combines laughter and fun yoga can help lower pain in children receiving chemotherapy.
- Trial name
- CLAP (NCT07327138)
- Testing
- Laughter and Fun Yoga Program
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Bahaa Bou Dargham
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