Clinical trials: Cancer Pains
Esophageal Carcinoma, Hypopharyngeal Carcinoma
Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy
This randomized pilot clinical trial studies the effects of taking doxepin hydrochloride as compared to placebo (inactive drug) in treating esophageal pain in patients with cancer located in the chest area receiving radiation…
- Conditions
- Esophageal Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Carcinoma, Lymphoma
- Trial name
- NCT02062632
- Testing
- Doxepin Hydrochloride, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Breast Cancer, Breast Cancer Female
Factors Affecting Functionality in Breast Cancer Survivors
Breast cancer is the most frequent cancer type in women globally. In conjunction with the new developments, breast cancer survival has increased therefore the management of long-term complications has gained importance.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Cancer Lymphedema, Breast Carcinoma in Situ
- Trial name
- NCT04245657
- Testing
- Tissue Dielectric Constant Measurement, Muscle strength measurement, Hand-Grip Strength Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Izmir Bakircay University
Breast Cancer
Evaluation of the Impact of the Use of Hypnotherapy Performed by a Virtual Reality Toolalong the Care Pathway of Patients Undergoing Breast Cancer Treatment.
In 2017, it is estimated that nearly 60,000 new cases of breast cancer will be diagnosed in France. Although several treatments are indicated in this context, chemotherapy remains a curability option whose place today extends to…
- Trial name
- HYGEE (NCT04574609)
- Testing
- Oncomfort® clinical virtual reality
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Pediatric Tumor
Use of Virtual Reality in Pain Management in Pediatric Oncology
DOREVI is a monocentric randomized controlled study that will evaluate the efficacy of virtual reality helmets for pain prevention during invasive care on 78 oncologic pediatric patients.
- Trial name
- DOREVI (NCT05592132)
- Testing
- Virtual reality headset
- Where
- Reunion
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Bone Metastases, Bone Neoplasm
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases
The FURTHER study aims to evaluate the effectiveness and cost-effectiveness of MR-HIFU (alone or in combination with EBRT) compared to EBRT alone, the standard-of-care, as a palliative treatment option to relieve CIBP.
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer
- Trial name
- FURTHER (NCT04307914)
- Testing
- External beam radiotherapy, MR-HIFU
- Where
- 6 sites in Finland, Germany and 2 more
- Volunteers
- 216 people
- Sponsor
- UMC Utrecht
Pain, Supratentorial Brain Tumor
Effects of Pre-emptive Scalp Infiltration With Low-dose Ketorolac and Ropivacaine for Postoperative Pain
The PAINLESS study is a single-center, prospective, randomized, open-label, blinded-endpoint (PROBE) controlled clinical pilot study to compare the efficacy and safety of pre-emptive scalp infiltration with ropivacaine plus…
- Trial name
- PAINLESS (NCT04380298)
- Testing
- Ketorolac, Ropivacaine, Epinephrine
- Volunteers
- 40 people
- Sponsor
- Beijing Tiantan Hospital
Colorectal Cancer
Late Organ Specific Adverse Effects hiPec or pElvic eXenteration
The purpose of this study is to describe type and extent of organ specific late adverse effects in patients undergoing surgery for colorectal cancer with peritoneal metastases and after surgery for colorectal cancer with…
- Trial name
- LOSAPEX (NCT04970316)
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 225 people
- Sponsor
- University of Aarhus
Polycystic Ovarian Syndrome
Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.
The study will be a non-blinded randomized controlled trial, consisting of two groups. Non-probability Convenience sampling will be used to recruit participants who will meet the inclusion criteria.
- Trial name
- NCT07645014
- Testing
- Neurodynamic stretches, myofascial pain release technique Interventions:
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Chemotherapeutic Agent Toxicity, Neurotoxicity
Acute Pain Caused by Paclitaxel in Patients With Cancer
RATIONALE: Gathering information over time from patients receiving paclitaxel for cancer may help doctors learn more about pain caused by paclitaxel and plan the best treatment.
- Conditions
- Chemotherapeutic Agent Toxicity, Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00860041
- Testing
- pain questionnaires
- Where
- 279 sites in United States
- Volunteers
- 306 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Arachnoiditis
Use of Thalidomide in Patients With Arachnoiditis
This pilot study will evaluate whether thalidomide decreases pain in patients with arachnoiditis.
- Trial name
- NCT00284505
- Testing
- thalidomide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Washington University School of Medicine
Hepatocellular Carcinoma, Transarterial Chemoembolization
Effect of Esketamine on Abdominal Pain During TACE-HAIC in Patients With Hepatocellular Carcinoma
Previous studies have confirmed that limb pain caused by oxaliplatin chemotherapy is related to spinal cord central sensitization - induced hyperalgesia through oxaliplatin activating spinal cord NMDA receptor(N-methyl-D-aspartic…
- Conditions
- Hepatocellular Carcinoma, Transarterial Chemoembolization, Hepatic Arterial Infusion Chemotherapy, Pain
- Trial name
- TACE-HAIC (NCT05416073)
- Testing
- Esketamine, Sufentanil
- Where
- China
- Volunteers
- 70 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Breast Cancer
The Effect of Metoprolol on Anaesthesia, the Need for Analgesics, and Pain in Breast Cancer Patients
The purpose of the study is to test the effects of metoprolol on anaesthesia and the need for perioperative analgesics in patients undergoing breast surgery.
- Trial name
- NCT02269696
- Testing
- Metoprolol, Normal saline
- Sponsor
- Kuopio University Hospital
Myofascial Pain Syndrome, Breast Cancer
Myofascial Pain Syndrome in Patients With Breast Cancer-related Lymphedema
The goal of this observational study is to determine the relationship between Lymphedema and Myofascial Pain Syndrome in Breast Cancer Patients.
- Conditions
- Myofascial Pain Syndrome, Breast Cancer, Breast Cancer Female, Lymphedema
- Trial name
- NCT06012786
- Testing
- Diagnostic Criteria of Myofascial Pain Syndrome, The Physical Examination of Trigger Points and Pain-Pressure Threshold Measurement With an Algometer, Hand Grip Test
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Chronic Pain Syndrome, Chronic Pain
Supporting Self-management of Chronic Pain
Does the Navigator Tool Intervention improve communication regarding self-management during consultations between healthcare professionals and people with chronic pain? As there is usually no cure for chronic pain, healthcare…
- Conditions
- Chronic Pain Syndrome, Chronic Pain, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- NCT03119896
- Testing
- The Navigator Tool Intervention
- Where
- 5 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- Pain Concern
Hyperalgesia, Pain
Effects of N-Methyl-D-Aspartate (NMDA)-Receptor Antagonism on Hyperalgesia, Opioid Use, and Pain After Radical Prostatectomy
The primary aim is to determine whether perioperative NMDA-receptor antagonism has differential effects on postoperative pain, hyperalgesia and morbidity in younger and older patients.
- Conditions
- Hyperalgesia, Pain, Prostate Cancer
- Trial name
- NCT00188383
- Testing
- Amantadine
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- University Health Network, Toronto
Chronic Pain
Self-Management Interventions for Chronic Pain Relief With Cancer Survivors
Cancer survivors who suffer from chronic pain would benefit from a low-cost, self-management intervention they can use at home. This study will evaluate the efficacy of a recorded hypnosis intervention in reducing chronic pain…
- Trial name
- NCT03867760
- Testing
- Recorded Hypnosis Intervention, Recorded Relaxation Intervention
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- University of Washington
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Cerebral Tumor
The Effects of Gabapentin Premedication on Neurosurgery
The study is to observe the effects of gabapentin premedication on postoperative pain,vomiting and nausea in patients undergoing neurosurgery. 100 neurosurgical patients are randomized into groups gabapentin(GG) or placebo(GP).
- Trial name
- NCT02306278
- Testing
- gabapentin, vitamin capsules
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Capital Medical University
Skin Carcinoma, Skin Cancer
Itch and Pain Characteristics in Skin Carcinomas
The objective of this study is to have better knowledge about sensations of patients with skin carcinomas and to have data about characteristics of pain and pruritus .
- Conditions
- Skin Carcinoma, Skin Cancer, Pruritus
- Trial name
- PRURITCC (NCT03290989)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Cancer Survivors, Peripheral Neuropathic Pain
Evaluating Laser Photobiomodulation for the Treatment of Neuropathic Pain in Chemotherapy-induced Peripheral Neuropathy in Cancer Patients
Chemotherapy-induced peripheral neuropathy (CIPN) (including taxanes, platinum, al pervenche from Madagascar alkaloids...), is a frequent secondary effect of treatments: 68% at 1-month post-chemotherapy, 60% at 3 months and 30%…
- Trial name
- NEUROdoux (NCT06834685)
- Testing
- Photobiomodulation sessions
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
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