Clinical trials: Cancer Palliative Care
Survivorship, Breast Cancer
The LYSA (Linking You to Support and Advice) Trial
This study's aim is to evaluate the feasibility of introducing a women's malignancy survivorship clinic incorporating symptom management through ePRO collection (complex intervention) into routine follow up care in patients with…
- Conditions
- Survivorship, Breast Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LYSA (NCT05035173)
- Testing
- Survivorship Clinic Assessments, Survivorship Clinic Nurse Resource, Survivorship Clinic Dietitian Resource
- Where
- Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College Cork
Oncology
Pilot Trial of Virtual and In-person STEP2
The goal of this clinical trial is to assess the feasibility of offering oncology patients a referral to the outpatient palliative care clinic based on virtual symptom screening before oncology clinic appointments, and to…
- Trial name
- STEP2 (NCT06326554)
- Testing
- Virtual and in-person Symptom screening with Targeted Early Palliative care (STEP2)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Non-Small Cell Lung Cancer
Effect of Celecoxib on Survival in Patients With Advanced Non-Small Cell Lung Cancer Receiving Chemotherapy
The primary purpose of the study is to investigate if daily treatment with celecoxib, an inhibitor of cyclooxygenase-2, can prolong survival in patients with advanced non-small cell lung cancer who receive anticancer chemotherapy…
- Trial name
- CYCLUS (NCT00300729)
- Testing
- Celecoxib
- Where
- 13 sites in Sweden
- Volunteers
- 319 people
- Sponsor
- University Hospital, Linkoeping
Cancer Disease, Palliative Therapy
Assessment of Disease Burden and Palliative Care Needs of Patients During the Course of Incurable Cancer Disease
The aim of this non-investigational study is to determine the symptoms and disease burden at the time point of diagnosis and in the further course of an incurable cancer disease.
- Trial name
- APM-Project (NCT02751723)
- Testing
- validated questionnaires
- Where
- 21 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Florian Lordick, MD
Metastatic Cancer
Prospective Validation of a Points Score System Predicting 30-day Survival
This is a one-stage single-arm phase II clinical trial designed to prospectively test the survival prediction tool as developed by Lee et al on patients referred to radiation oncology for palliative treatments.
- Trial name
- NCT05100342
- Testing
- Point score prediction tool for 30-day survival
- Where
- 3 sites in United States
- Volunteers
- 214 people
- Sponsor
- Indiana University
Carcinoma, Non-Small-Cell Lung
Palliative Thoracic Radiotherapy Plus BKM120
This study will test whether a drug called BKM120/buparlisib is a safe and effective treatment when given to lung cancer patients having radiotherapy treatment.
- Trial name
- BKM120 (NCT02128724)
- Testing
- BKM120
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Oxford
Hematologic Malignancy
Impact of Palliative Transfusions on Quality of Life in Patients With Blood Cancers on Hospice
The purpose of this pilot research study is to evaluate the effectiveness of blood and platelet transfusions in improving symptoms and quality of life of patients enrolled in hospice.
- Trial name
- PalliaQOL (NCT04454723)
- Testing
- Blood and/or platelet transfusion, Complete blood count (CBC) collection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oklahoma
Acute Myeloid Leukemia
Feasibility of Telehealth Palliative Care and Digital Symptom Monitoring for Patients With Acute Myeloid Leukemia
AML is the most common leukemia diagnosed in adults. In spite of recent low-intensity therapies that have improved outcomes for older AML patients, AML remains associated with poor prognosis as well as high symptom burden.
- Trial name
- NCT04885127
- Testing
- Palliative Care + Digital Symptom Monitoring
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Dyspnea
Trial of a Breathlessness Intervention Service for Intractable Breathlessness
The aim of this study is to evaluate the impact of a Breathlessness Intervention Service (BIS) on the quality of life of patients and families affected by intractable breathlessness.
- Trial name
- NCT00678405
- Testing
- Breathlessness Intervention Service, Best supportive care (Standard Care)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Mucinous Ovarian Cancer, Fallopian Tube Cancer
Bevacizumab Plus Modiifed FOLFIRINOX in Ovarian, Fallopian Tube, or Primary Peritoneal Mucinous Carcinoma
This research study is evaluating a modified FOLFIRINOX plus bevacizumab therapy for mucinous ovarian cancer, fallopian tube cancer, and primary peritoneal cancer.
- Conditions
- Mucinous Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
- Trial name
- NCT05665023
- Testing
- Bevacizumab + modified FOLFIRINOX
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Yonsei University
Cancer, Congestive Heart Failure
Expanding Access to Home-Based Palliative Care
This study will test the effectiveness of integrating an evidence-based model of home-based palliative (HBPC) within primary care clinics on patient and caregiver outcomes.
- Conditions
- Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT03128060
- Testing
- Home-based palliative care, Enhanced usual care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Southern California