Clinical trials: Cancer Patient
Neurofibromatosis 2, Vestibular Schwannoma
Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors
In this research study the researchers want to learn more about the effects (both good and bad) the study drug selumetinib has on participants with neurofibromatosis type II (NF2) related tumor.
- Conditions
- Neurofibromatosis 2, Vestibular Schwannoma, Meningioma, Ependymoma
- Trial name
- SEL-TH-1601 (NCT03095248)
- Testing
- Selumetinib
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Ovarian Cancer
Maintenance Therapy After Platinum-containing Chemotherapy in Patients With Recurrent Ovarian Cancer
Thirty-seven women aged 18-75 years with recurrent ovarian cancer were enrolled
- Trial name
- NCT06188455
- Testing
- Fluzoparib Capsules, Apatinib Mesylate Tablets
- Volunteers
- 37 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Malnutrition, Calorie, Malnutrition; Protein
The Impact of Artificial Intelligence Dietary Smartphone Application on Nutritional Status Among Cancer Patients
Multi-center prospective pilot trial study
- Conditions
- Malnutrition, Calorie, Malnutrition; Protein, Weight Change, Body
- Trial name
- NCT04643626
- Testing
- artificial intelligence dietary android mobile application
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- Universiti Putra Malaysia
Breast Cancer, Locally Advanced Breast Cancer (LABC)
Patient-Derived Organoids to Functionally Characterize Chemotherapy Resistance in Breast Cancer
This prospective observational study aims to functionally characterize chemotherapy resistance in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy.
- Trial name
- BC-PDO (NCT07516626)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Prostate Cancer, Castrate Resistant Prostate Cancer
Study Evaluating Sodium Selenite in Combination With Abiraterone in Castrate Resistant Prostate Cancer Progressing on Abiraterone
The purpose of this study is to access the safety of combining sodium selenite with abiraterone and to see what doses of sodium selenite can be safely combined with abiraterone in treating castration resistant prostate cancer.
- Trial name
- NCT04296578
- Testing
- Abiraterone Acetate, Sodium Selenite, Prednisone
- Sponsor
- Stanford University
Solid Cancers, Solid Tumours
A Study to Evaluate the Safety and Tolerability of EP0089
This is a first-in-human (FIH), first-in-class, Phase I/IIa, open-label study designed to evaluate the safety and tolerability of EP0089 (study drug).
- Trial name
- NCT07030478
- Testing
- EP0089-101
- Volunteers
- 190 people
- Sponsor
- Ellipses Pharma
Breast Cancer, Breast Neoplasms
Evaluation of the Impact of a Multidimensional ICT Intervention on the Quality of Life of Breast Cancer Survivors
mACMA is a pilot study that is developed for breast cancer survivors of the Hospital Clinic of Barcelona. The objective of this study is to evaluate the progress in quality of life through the introduction of a mobile phone App…
- Conditions
- Breast Cancer, Breast Neoplasms, Quality of Life, Survivorship
- Trial name
- NCT05401643
- Testing
- Xemio mobile application
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Glioblastoma
A Dose Escalation Phase I Study Of Human- Recombinant Bone Morphogenetic Protein 4 Administrated Via CED In GBM Patients
The purpose of the study is to evaluate the feasibility and safety of intra-tumor and interstitial therapy with hBMP4 in increasing doses in patients with progressive and/or multiple recurrent Glioblastoma multiforme (GBM).
- Trial name
- NCT02869243
- Testing
- hrBMP4
- Where
- 4 sites in Israel, Italy and 1 more
- Volunteers
- 15 people
- Sponsor
- Stemgen
Lung Cancer
T138067 in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer That Has Not Responded to Previous Chemotherapy
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of T138067 in treating patients who have locally advanced…
- Trial name
- NCT00022243
- Testing
- batabulin sodium
- Where
- 2 sites in United States
- Sponsor
- Tularik
Tumor, Brain
Multimodal Connectome Study of Brain Tumor-operated Patients
In this pilot study, the investigators propose a multimodal evaluation of the brain connectivity of brain tumor patients, in order to better understand the effects induced by focal lesions on brain structure and function, as well…
- Trial name
- ConnecTC (NCT04163315)
- Testing
- dMRI, fMRI and electrocorticography
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Colorectal Cancer, Diarrhea
Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy
RATIONALE: Drugs used in chemotherapy, such as fluorouracil, oxaliplatin, and leucovorin calcium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Colorectal Cancer, Diarrhea, Neutropenia
- Trial name
- NCT01164215
- Testing
- fluorouracil, leucovorin, oxaliplatin
- Where
- 5 sites in United States
- Volunteers
- 76 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Neoplasms
A Safety Study of Oral ZSTK474 in Patients With Cancer
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary efficacy of daily oral doses of ZSTK474, an oral phosphatidylinositol 3-kinase (PI3K) inhibitor, in subjects with advanced…
- Trial name
- NCT01280487
- Testing
- ZSTK474
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- Zenyaku Kogyo Co., Ltd.
Cancer
Efficacy Of An Inpatient Yoga Therapy Program For Cancer Patients
The purpose of this study is to learn whether a yoga therapy program can improve quality of life and reduce symptoms in people undergoing stem cell transplantation compared with an enhanced standard care physical activity program.
- Trial name
- NCT07776587
- Testing
- Yoga Therapy (YT)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- M.D. Anderson Cancer Center
Lymphoma
Combination Chemotherapy Given With Radiation Therapy or Radiation Therapy Alone in Treating Patients With Early-Stage Hodgkin's Disease
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells.
- Trial name
- NCT00002987
- Testing
- bleomycin sulfate, cyclophosphamide, doxorubicin hydrochloride
- Where
- 18 sites in South Africa, United Kingdom
- Volunteers
- 400 people
- Sponsor
- Medical Research Council
Breast Cancer Metastatic
Prevention of Sacituzumab Govitecan-related Neutropenia in Patients With Metastatic Triple Negative Breast Cancer
Prevention of Sacituzumab Govitecan-related Neutropenia in Patients with metastatic Triple Nagative Breast Cancer who have received at least one, and no more than two, prior standard of care chemotherapy regimens
- Trial name
- NCT06616987
- Testing
- Sacituzumab Govitecan with pegfilgrastim
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yeon Hee Park
Advanced Malignancies
IBI397 or Combination Therapies in Patients With Advanced Malignancies
The primary objective of this phase Ia/Ib Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of IBI397 or its Combination Therapies in Patients with Advanced Malignancies
- Trial name
- NCT05245916
- Testing
- IBI397, IBI397+Sintilimab, IBI397+Rituximab
- Where
- China
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Prostate, Prostate Cancer
Focal Therapy in Localized Prostate Cancer: a Prospective Registry
The principal aim of the registry is to collect data on focal therapy (FT) for the treatment of intermediate-risk prostate cancer across Europe.
- Trial name
- JR (NCT06772116)
- Testing
- Focal Therapy
- Volunteers
- 1,000 people
- Sponsor
- Institut Mutualiste Montsouris
Colorectal Cancer
Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer
RATIONALE: Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as panitumumab, can block tumor growth in different ways.
- Trial name
- NCT00940316
- Testing
- panitumumab, erlotinib hydrochloride, irinotecan hydrochloride
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- Northwestern University
Depression, Unspecified Adult Solid Tumor, Protocol Specific
Depression Screening in Patients Undergoing Radiation Therapy For Cancer
RATIONALE: Gathering information about depression in patients with cancer may help doctors learn more about the disease and plan the best treatment.
- Trial name
- NCT00951184
- Testing
- telephone-based intervention, screening questionnaire administration, study of socioeconomic and demographic variables
- Where
- 16 sites in United States
- Volunteers
- 463 people
- Sponsor
- Radiation Therapy Oncology Group
Esophageal Cancer
Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00002884
- Testing
- chemotherapy, cisplatin, fluorouracil
- Where
- France
- Volunteers
- 326 people
- Sponsor
- Centre Hospitalier Lyon Sud
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