Clinical trials: Cancer Patient
Blood Stream Infection, Gut Microbiota
Application of Nanopore Sequencing in Newly Diagnosed Acute Myeloid Leukemia Patients With Bloodstream Infection
Acute myeloid leukemia (AML) patients are prone to blood stream infection (BSI) due to bone marrow suppression, oral and gastrointestinal mucositis, endovascular tubes, and the application of a large number of broad-spectrum…
- Conditions
- Blood Stream Infection, Gut Microbiota, Acute Myeloid Leukemia
- Trial name
- NCT05016752
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Advanced Solid Tumors, Ovarian Cancer
Alisertib (MLN8237) in Combination With Weekly Paclitaxel in East Asian Patients With Advanced Solid Tumors
The purpose of this study is to evaluate the safety and tolerability and determine the MTD to subsequently define an RP2D of alisertib in combination with weekly paclitaxel in East Asian participants with advanced solid tumors.
- Conditions
- Advanced Solid Tumors, Ovarian Cancer, Small Cell Lung Cancer
- Trial name
- NCT02367352
- Testing
- Alisertib, Paclitaxel
- Where
- 3 sites in Japan, South Korea
- Volunteers
- 9 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Brain Tumors
Frailty as a Predictor of Neurosurgical Outcomes in Brain Tumor Patients
Frailty as an adjunct to preoperative assessment of neurosurgical patients has never been evaluated. This study aims to determine if frailty predicts neurosurgical complications in brain tumor patients and enhances current…
- Trial name
- NCT02530749
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- University of Colorado, Denver
Prostate Cancer (Post Prostatectomy)
Effect of Education to be Provided to Patients to Undergo TURP With Mobile Application on Patient Outcomes
The aim of this study was to determine the effect of mobile application training on patient outcomes (preoperative anxiety, surgical fear, postoperative pain, hemodynamic parameters, satisfaction level and length of hospital…
- Trial name
- NCT06687538
- Testing
- Mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Malignant Tumors
Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors
The purpose of this study is to evaluate the efficacy and safety of mRNA vaccine for the EBV-positive Advanced Malignant Tumors.
- Trial name
- NCT05714748
- Testing
- EBV mRNA vaccine
- Where
- China
- Volunteers
- 19 people
- Sponsor
- West China Hospital
Medical Oncology, Integrative Oncology
A Pilot, Feasibility Study of Intermittent Caloric Restriction Plus Plant-based Diet in Cancer Patients Receiving Chemotherapy
Caloric restriction may alter the response to chemotherapy induced stress response and enhance its antitumor effect. This study intends to use an intermitted caloric restriction protocol with alternate days before the…
- Conditions
- Medical Oncology, Integrative Oncology, Medical Nutrition Therapy
- Trial name
- NCT05359848
- Testing
- Diet
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- State University of New York at Buffalo
Neurofibromatosis 1, Neurofibroma
Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1
This study is being conducted to determine if Whole Body MRI (WBMRI) can be used to identify Atypical Neurofibromas (ANF) in Neurofibromatosis Type 1 (NF1) patients with high tumor burden.
- Conditions
- Neurofibromatosis 1, Neurofibroma, Atypical Neurofibroma, Atypical Neurofibromatosis
- Trial name
- NCT03820778
- Testing
- Whole Body MRI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's National Research Institute
Renal Cell Carcinoma
Stereotactic Body Radiotherapy (SBRT) and Sorafenib in Patients With Metastatic, Recurrent, or Unresectable Renal Cell Cancer (RCC)
The purpose of this study is to determine the safety and efficacy of combined stereotactic body radiotherapy (SBRT) + sorafenib in the treatment of patients with Stage IV renal cell carcinoma (RCC) who have recurred locally…
- Trial name
- NCT00672178
- Testing
- Stereotactic body radiation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Duke University
Cancer, Emergencies
Pro-active Monitoring of Vital Signs in Oncology Patients Using a Smartwatch
The goal of this single center prospective observational study is to determine the effect of chemotherapy on (the change in) vital parameters.
- Trial name
- PROGRESS (NCT06680778)
- Testing
- Proactive Monitoring
- Where
- Netherlands
- Volunteers
- 175 people
- Sponsor
- Erasmus Medical Center
Metastatic Breast Cancer
Phase II Study of Ixabepilone in Metastatic Breast Cancer and Its Effects on the Ultrastructure of Neurons
Primary Objectives Assess ultrastructure changes in dermal myelinated nerves of patients who receive ixabepilone chemotherapy Detailed characterization of peripheral neuropathy in patients who receive ixabepilone Secondary…
- Trial name
- NCT00627978
- Testing
- ixabepilone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Lymphoma
Filgrastim and Chemotherapy Followed by Peripheral Stem Cell Transplant in Treating Patients With Hodgkin's Lymphoma or Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplant may allow the doctor to give higher doses of…
- Trial name
- NCT00005985
- Testing
- filgrastim, carmustine, cyclophosphamide
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Malnutrition, Cancer
Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients
This study aims to compare nutritional outcomes in terms of percentage of weight gain between a new planted-based high-energy ONS and a standard high-energy ONS with animal protein (cow's mil protein) in patients at malnutrition…
- Conditions
- Malnutrition, Cancer, Inflammatory Bowel Diseases, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06055543
- Testing
- Fortimel
- Where
- 6 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Danone Specialized Nutrition
Prostate Cancer
Conducting Active Surveillance Without Prostate Biopsy for Patients With Low-risk Suspected Prostate Cancer
The goal of this observational study is to evaluate the role of the USTC diagnostic model in risk-adaptive strategies for biopsy decision-making in patients with low-risk suspected prostate cancer in order to reduce unnecessary…
- Trial name
- ASWBP (NCT05940415)
- Testing
- active surveillance
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Anhui Provincial Hospital
Brain and Central Nervous System Tumors
Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
RATIONALE: Radiolabeled monoclonal antibodies, such as iodine I 131 monoclonal antibody TNT-1/B (^131I MOAB TNT-1/B), can find tumor cells and carry tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00128635
- Testing
- iodine I 131 monoclonal antibody TNT-1/B
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Resectable Esophageal Cancer
Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection
This research study is evaluating a new type of esophagus cancer vaccine called "Personalized Neoantigen Cancer Vaccine" as a possible treatment for esophagus cancer patients who have completed adjuvant therapy following…
- Trial name
- NCT05307835
- Testing
- iNeo-Vac-P01, GM-CSF
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Gastrointestinal Disease, Esophageal Cancer
FDG-PET-CT and Biomarkers in Esophageal Cancer
The goal of this clinical research study is to learn if the results of a positron emission tomography/computed tomography (PET/CT) scan done 10-14 days after beginning chemotherapy and radiation (chemoradiation) can predict how a…
- Trial name
- NCT00833625
- Testing
- PET/CT (FDG PET/CT), Biomarker Testings
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Cancer
Training of Arms to Reduce Pain With Peripheral Venous Catheter
Female patients undergoing chemotherapy for breast cancer often experience pain and discomfort when a peripheral venous catheter is inserted.
- Conditions
- Pain, Cancer, Veins
- Trial name
- NCT05716217
- Testing
- Arm training
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Vejle Hospital
Pancreatic Cancer
Immunotherapy Combined With Radiation and Influenza Vaccine for Pancreatic Cancer.
Pancreatic cancer (PC) remains a dreadful disease due to its often advanced stage at diagnosis and poor sensitivity to chemotherapy. Progression after 1.
- Trial name
- INFLUENCE (NCT05116917)
- Testing
- Nivolumab, Ipilimumab, Influenza vaccine
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- Herlev Hospital
Head and Neck Squamous Cell Carcinoma
Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma
This is a prospective, open-labelled study to evaluate the efficacy and safety of camrelizumab combined with apatinib mesylate in the induction treatment of patients with locally advanced head and neck squamous cell carcinoma who…
- Trial name
- IMplus (NCT04440917)
- Testing
- Camrelizumab, Apatinib Mesylate
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Breast Cancer, Lung Cancer
Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2
The goal of this clinical trial is to explore feasibility, acceptability, and effectiveness of end-of-life conversation game "Hello" as a tool to help individuals with various solid cancer types (including: breast…
- Conditions
- Breast Cancer, Lung Cancer, Genito-Urinary Cancer, Colorectal Cancer
- Trial name
- NCT06384417
- Testing
- Hello for Cancer game, Table Topics game
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Milton S. Hershey Medical Center
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