Clinical trials: Cancer Patients With Cancer Pain
Castration-Resistant Prostatic Cancer
Pain Evaluation in Radium-223 Treated Castration Resistant Prostate Cancer Patients With Bone Metastases
This observational prospective single arm cohort study is designed to assess pain and bone pain related quality of life of metastatic Castration Resistant Prostate Cancer (mCRPC) patients receiving Radium-223 in a real life…
- Trial name
- PARABO (NCT02398526)
- Testing
- Radium-223 dichloride, (Xofigo, BAY88-8223)
- Where
- Germany
- Volunteers
- 363 people
- Sponsor
- Bayer
Leukemia, Lymphoma
Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies
The purpose of this project is to assess the efficacy of loratadine in decreasing the incidence and severity of bone pain following G-CSF administration in patients with hematologic malignancies, patients undergoing mobilization…
- Trial name
- NCT02305979
- Testing
- Loratadine
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Wake Forest University Health Sciences
Opioid-induced Constipation
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
This study will evaluate the safety and efficacy of Tegaserod in opioid-induced constipation (OIC) in patients with non-cancer pain.
- Trial name
- NCT00399659
- Testing
- Tegaserod
- Where
- 57 sites in United States
- Volunteers
- 360 people
- Sponsor
- Novartis
Breast Cancer
Music Therapy in Patients With Breast Cancer (IMPACT)
This study aims to evaluate the feasibility and potential benefits of music therapy in patients with breast cancer undergoing adjuvant chemotherapy.
- Trial name
- IMPACT- (NCT07549685)
- Testing
- Music Therapy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Istituto di Studi Superiori Musicali (ISSM) Conservatorio Antonio Vivaldi di Alessandria
Cancer
Radiofrequency Splanchnic Denervation ,Neurolytic Retrocrural Celiac Plexus Block Chronic Upper Abdominal Cancer Pain
To compare between the efficacy of radiofrequency splanchnic denervation and neurolytic retrocrural celiac plexus block in chronic upper abdominal cancer pain
- Trial name
- NCT06678061
- Testing
- radiofrequency
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pain
Evaluation of the Efficacy and Safety of Fentanyl Delivered by Adhesive Skin Patch in Out-Patients With Chronic Cancer Pain
The purpose of this study is to determine the safety and efficacy of pain control by fentanyl, administered via adhesive skin patches, at doses of 25 to 100 micrograms per hour in 80 out-patients with intense chronic cancer pain.
- Trial name
- NCT00236327
- Testing
- fentanyl
- Volunteers
- 34 people
- Sponsor
- Janssen Cilag S.A.S.
Postoperative Pain, Breast Cancer
Comparison of Erector Spinae Plane Block With Serratus Anterior Plane Block for Breast Surgery
Breast cancer is by far the world's most common cancer among women and the most common cause of female death from cancer worldwide. It's worldwide incidence is 43.4 in 100.000 while in Egypt is 48.8 in 100.000.
- Trial name
- NCT03579524
- Testing
- Erector Spinae Plane Block, Serratus Anterior Plane Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Fayoum University Hospital
Lung Cancer
Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer
The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.
- Trial name
- NCT05478460
- Testing
- Hookwire localization
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Fudan University
Pain, Postoperative
Rhomboid Intercostal Block Compared With Thoracic Paravertebral Block in Breast Cancer Surgeries
Postoperative pain is a significant problem following breast surgery . If not treated in time, it may lead to delayed wound healing, respiratory depression, hemodynamic disorders, anxiety,other complications, and finally lead to…
- Trial name
- NCT06781346
- Testing
- Rhomboid Intercostal Block, Thoracic Paravertebral Block
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Breakthrough Cancer Pain
Instanyl® Non-Interventional Study
The aim of this study is to describe the use of Instanyl® (Intranasal fentanyl spray) in the treatment of breakthrough pain (BTP) in cancer patients by success of dose titration and distribution of dose strength.
- Trial name
- INIS (NCT01045603)
- Where
- 65 sites in Denmark, France and 5 more
- Volunteers
- 309 people
- Sponsor
- Takeda
Opioid-Induced Constipation
Safety and Preliminary Efficacy of BGP345A in Constipation Due to Opioid-based Medications
The purpose of this study is to assess safety and preliminary efficacy of BGP345A in patients with constipation due to the use of opioid-based medications for the management of chronic non cancer pain.
- Trial name
- OIC1 (NCT05133076)
- Testing
- Lactobacillus gasseri BGP345A
- Where
- 4 sites in France
- Volunteers
- 14 people
- Sponsor
- BioGaia Pharma AB
Cancer, Pain
An Efficacy and Safety Study of Hydromorphone Hydrochloride (HCl) Oral Osmotic System (OROS) in the Reduction of Breakthrough Pain Medication Frequency in Participants With Cancer
The purpose of this study is to evaluate the clinical efficacy of hydromorphone hydrochloride (HCl) Oral Osmotic System (OROS) by assessing the extent of reduction of medication frequency for the management of breakthrough pain…
- Trial name
- NCT01006356
- Testing
- Hydromorphone HCl OROS
- Volunteers
- 141 people
- Sponsor
- Janssen Korea, Ltd., Korea
Chemotherapy-induced Neutropenia
Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 3
To assess Duration of Severe Neutropenia (DSN) in treatment Cycle 1 in patients with advanced or metastatic breast cancer, who have failed >/= 1 but < 5 prior lines of chemotherapy; locally advanced or metastatic non small cell…
- Trial name
- Protective-1 (NCT03102606)
- Testing
- Plinabulin, Pegfilgrastim
- Where
- 18 sites in United States, China and 2 more
- Volunteers
- 105 people
- Sponsor
- BeyondSpring Pharmaceuticals Inc.
Hematopoietic/Lymphoid Cancer, Pain
Opioids With or Without Olanzapine in Treating Patients With Moderate to Severe Cancer Pain
RATIONALE: Opioids lessen pain caused by cancer. It is not yet known whether opioids are more effective when given together with or without olanzapine in treating cancer pain.
- Conditions
- Hematopoietic/Lymphoid Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00737191
- Testing
- olanzapine
- Sponsor
- Mayo Clinic
Neoplasms, Bone Tissue, Pain, Intractable
Study of the Impact of the Femoral Implant "Y-strut" on Lytic Bone Metastases of the Femoral Neck (WAZA-ARY)
Bone metastases appear in many cancers. They are associated with severe pain that is refractory to standard treatment. Improving the quality of life and better pain relief is therefore an essential goal of the treatment of…
- Conditions
- Neoplasms, Bone Tissue, Pain, Intractable, Hip Fractures
- Trial name
- WAZA-ARY (NCT03887494)
- Testing
- Implantation
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer Pain
Endovascular Denervation in Patients With Cancer Pain
Endovascular arterial denervation (ED) is a minimally invasive technique which could reduce the occurrence of injury of visceral tissue or organs.
- Trial name
- NCT03431922
- Testing
- endovascular denervation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhongda Hospital
Brain and Central Nervous System Tumors, Chordoma
Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer
RATIONALE: Polyvinylpyrrolidone-sodium hyaluronate gel may lessen the pain of oral mucositis, or mouth sores, in patients undergoing treatment for cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chordoma, Kidney Cancer, Leukemia
- Trial name
- NCT00349024
- Testing
- polyvinylpyrrolidone-sodium hyaluronate gel
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 50 people
- Sponsor
- Children's Cancer and Leukaemia Group
Pain
Conversion From Fast Acting Oral Opioids to Abstral®
The purpose of this study is to evaluate safety and efficacy when using a novel dose conversion strategy to switch from immediate release oral opioids to sublingual (SL) fentanyl (Abstral) for treatment of breakthrough cancer…
- Trial name
- NCT01315886
- Testing
- SL fentanyl
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Orexo AB
Anxiety Disorder, Depression
Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer
This pilot clinical trial studies stress reduction in improving quality of life in patients with recurrent gynecologic or breast cancer.
- Conditions
- Anxiety Disorder, Depression, Fatigue, Leydig Cell Tumor
- Trial name
- NCT01764789
- Testing
- questionnaire administration, quality-of-life assessment, psychosocial assessment and care
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Quality of Life, Chronic Cancer Pain
Effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation on Quality of Life in Chronic Cancer Pain
This study aims to objectively evaluate the effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation (PC-TEAS) on improving the quality of life in patients with chronic cancer pain, thereby providing…
- Trial name
- NCT07308951
- Testing
- TEAS
- Where
- China
- Volunteers
- 290 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University