Clinical trials: Cancer Patients With Cancer Pain
Laparoscopic Surgery, Gynecologic Oncology Patient
The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology
Laparoscopic surgery, characterized by minimal invasiveness, rapid recovery, and shorter hospital stays, has been widely adopted in Gynecologic Oncology.
- Conditions
- Laparoscopic Surgery, Gynecologic Oncology Patient, Liposomal Bupivacaine, Transversus Abdominis Plane Block
- Trial name
- NCT07458295
- Testing
- Bupivacaine hydrochloride, Liposomal bupivacaine plus bupivacaine
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tiantan Hospital
Neurotoxicity, Pain
Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
RATIONALE: Lamotrigine may be effective in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether lamotrigine is effective in treating peripheral neuropathy caused by…
- Conditions
- Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00068445
- Testing
- lamotrigine
- Where
- 23 sites in United States
- Volunteers
- 131 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Bone Metastasis, Cancer Pain
Phase 3 Study on the Efficacy and Safety of Tanezumab in Patients With Cancer Pain Due to Bone Metastasis Who Are Taking Background Opioid Therapy
The purpose of this study is to determine whether tanezumab is effective in the treatment of cancer pain due to bone metastasis in patients already taking background opioid therapy.
- Trial name
- NCT02609828
- Testing
- Tanezumab
- Where
- 89 sites in Argentina, Australia and 14 more
- Volunteers
- 156 people
- Sponsor
- Pfizer
Multiple Myeloma
Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma
Multiple myeloma is a plasma cell neoplasm that can cause painful bone lesions. The main treatment for these lesions and pain control is radiotherapy, usually in daily fractions.
- Trial name
- NCT05996367
- Testing
- Single-dose involved-site radiotherapy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Pancreatic Cancer, Retroperitoneal Pain Syndrome
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain
Participants who are experiencing abdominal pain due to having cancer in their pancreas may be eligible for this research study. For this type of pain, doctors often recommend radiation therapy to help with the pain.
- Trial name
- NCT07117032
- Testing
- Simulation-free workflow, Celiac plexus SBRT
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center
Breakthrough Pain, Cancer
Efficacy and Safety of Fentanyl ETHYPHARM for Breakthrough Pain in Opioid-treated Patients With Cancer
The purpose of the study is to assess the clinical effectiveness of Fentanyl ETHYPHARM when used to relieve breakthrough pain (BTP) in opioid-treated cancer patients.
- Trial name
- ETHYFYL (NCT01842893)
- Testing
- Fentanyl Ethypharm
- Where
- Czechia
- Volunteers
- 91 people
- Sponsor
- Ethypharm
Advanced Cancers, Pain
Compare Fentanyl Nasal Spray With Intravenous Opioids to Treat Severe Pain
The goal of this clinical research study is to compare fentanyl nasal spray with a standard drug given by vein (hydromorphone hydrochloride) to help reduce pain related to cancer in patients coming to the emergency department.
- Trial name
- NCT02459964
- Testing
- Fentanyl Nasal Spray, Hydromorphone Hydrochloride, Phone Call
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- M.D. Anderson Cancer Center
Multiple Myeloma and Plasma Cell Neoplasm, Pain
Samarium Sm 153 Lexidronam Pentasodium Combined With Zoledronic Acid or Pamidronate in Treating Patients With Relapsed or Refractory Multiple Myeloma and Bone Pain
RATIONALE: Radioactive drugs, such as samarium Sm 153 lexidronam pentasodium, may carry radiation directly to cancer cells and not harm normal cells.
- Trial name
- NCT00482378
- Testing
- Pamidronate, Zoledronic acid, Sm 153 lexidronam
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Tako-Tsubo Cardiomyopathy, Stress-induced Cardiomyopathy
The TAKO-TSUBO And Cancer Registry
Prospective, multicenter, observational registry collecting data from subjects with Tako-Tsubo (stress-induced) cardiomyopathy (TTC).
- Conditions
- Tako-Tsubo Cardiomyopathy, Stress-induced Cardiomyopathy, Acute Coronary Syndrome
- Trial name
- TTAC (NCT01944826)
- Testing
- Registry of patients with Tako-Tsubo cardiomyopathy
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Cancer Pain, Erector Spinae Plane Block
Intermittent Erector Spinae Plane Block Via Subcutaneous Port for Cancer Pain
Cancer-related pain is a common and challenging problem in patients with lung cancer, often requiring long-term pain management.
- Trial name
- NCT07396558
- Testing
- Erector Spinae Plane Block
- Where
- Vietnam
- Volunteers
- 180 people
- Sponsor
- Hanoi Medical University
Peripheral Neuropathy, Antineoplastic Combined Chemotherapy Protocols
Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Chemotherapy-Induced Neuropathy
This study was designed to evaluate the safety and efficacy of Cesamet™ in controlling pain in subjects experiencing pain due to chemotherapy-induced neuropathic pain in patients with cancer.
- Trial name
- NCT00380965
- Testing
- Cesamet™ (nabilone)
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- NEMA Research, Inc.
Chemotherapy-induced Peripheral Neuropathy, Pain
Efficacy and Safety of Duloxetine in Chinese Solid Tumor Patients With Taxanes-induced Painful Peripheral Neuropathy
The study is to evaluate the efficacy and safety of duloxetine in Chinese solid tumor patients with taxanes-induced painful peripheral neuropathy.
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Pain, Solid Tumor
- Trial name
- NCT04970121
- Testing
- Duloxetine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yan Yang, MD, Ph.D
Breast Cancer
Musculoskeletal Pain in Postmenopausal, Early Breast Cancer Patients Receiving Aromatase Inhibitor Therapy - A Pilot Study
In 2005, the EBCIG demonstrated the efficacy of tamoxifen in improving overall survival in hormone receptor positive breast cancers.
- Trial name
- AIMS (NCT00653718)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cancer, Constipation
Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)
The purpose of this study is to determine if naloxegol can be used in the treatment of opioid-induced constipation in patients with cancer and pain.
- Conditions
- Cancer, Constipation, Pain
- Trial name
- NCT02839889
- Testing
- Naloxegol
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Hospice of Henderson County, Inc.
Chemotherapy-Induced Peripheral Neuropathy, Malignant Neoplasm
Transcranial Direct Current Stimulation in Reducing Pain in Cancer Patients With Chemotherapy Induced Peripheral Neuropathy
This early phase I trial studies how well transcranial direct current stimulation works in reducing pain in cancer patients with chemotherapy induced peripheral neuropathy.
- Trial name
- NCT04135326
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Transcranial Direct Current Stimulation
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Pain, Cancer
Study to Compare the Safety and Tolerability of Sativex® in Patients With Cancer Related Pain
The purpose of this study is to assess the safety and tolerability of long term therapy with Sativex® and GW-2000-02.
- Trial name
- NCT00675948
- Testing
- Sativex, GW-2000-02
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Jazz Pharmaceuticals
Ductal Adenocarcinoma of Pancreas, Pancreatectomy
Patients With Pancreatic Tumor: Use of an App to Monitor Progress in a Simple and Intuitive Way by Periodically Completing Targeted Questionnaires and Providing Educational and Informational Content (PancreasPlus).
Caring for people with pancreatic cancer requires good coordination between hospital care and care at home, with different healthcare professionals working closely together.
- Conditions
- Ductal Adenocarcinoma of Pancreas, Pancreatectomy, Caregiver, Nutritional Evaluation
- Trial name
- NCT07532590
- Testing
- use of PancreasPlus app
- Where
- 2 sites in Italy
- Volunteers
- 185 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Nausea, Vomiting
Effect of a Symptom Diary on Symptom Care and Symptom Burden in Patients Treated With Chemotherapy: a Before-and-after-study
This study investigates whether the implementation of a symptom diary for reporting and communicating chemotherapy-related symptoms improves symptom care and decreases symptom burden in adult patients treated with chemotherapy.
- Conditions
- Nausea, Vomiting, Pain, Anorexia
- Trial name
- NCT02050490
- Where
- Belgium
- Volunteers
- 236 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Adenoma, Pain
Water Method in Low-body Mass Index (BMI) Female Patients With Unsedated Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Trial name
- NCT01546259
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China