Clinical trials: Cancer Patients With Cancer Pain
Pain, Cancer
Study of BEMA™ Fentanyl in the Treatment of Breakthrough Pain in Cancer Subjects
The purpose of this study is to evaluate the efficacy of BEMA Fentanyl (Onsolis) at any dose in the management of breakthrough pain in cancer subjects on background opioid therapy.
- Trial name
- NCT00293033
- Testing
- BEMA™
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- BioDelivery Sciences International
Bladder Spasm, Malignant Neoplasm
Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer
This pilot phase I trial studies the side effects and best dose of curcumin when given together with piperine (piperine extract [standardized]) in reducing inflammation for ureteral stent-induced symptoms in patients with cancer.
- Conditions
- Bladder Spasm, Malignant Neoplasm, Pain, Urinary Urgency
- Trial name
- NCT02598726
- Testing
- Curcumin, Laboratory Biomarker Analysis, Piperine Extract (Standardized)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Pain Cancer
Effectiveness of Percutaneous Neuromodulation vs Pharmacological Treatment in Cancer Patients With Anterior Knee Pain
the goal of this clinical trial is to compare in cancer patients: Is ultrasound-guided percutaneous neuromodulation useful for Anterior Knee Pain relief in cancer patients? Participants will receive treatments of…
- Trial name
- NCT06240390
- Testing
- Ultrasound-guided percutaneous neuromodulation (NMP), pharmacological treatment by Opioids
- Where
- Spain
- Sponsor
- Universidad Europea de Canarias
Breast Cancer, Cognitive Ability, General
Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer
RATIONALE: Radiation therapy uses high-energy x rays to kill tumor cells. Radiation therapy may cause skin reactions when patients are exposed to high-energy x rays.
- Conditions
- Breast Cancer, Cognitive Ability, General, Fatigue, Pain
- Trial name
- NCT01407770
- Testing
- DNA analysis, gene expression analysis, enzyme-linked immunosorbent assay
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Wake Forest University Health Sciences
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Ontario
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-ON (NCT02742597)
- Testing
- TIP / IMPACT Plus Care Coordination
- Where
- 9 sites in Canada
- Volunteers
- 175 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Opioid-Induced Constipation, Pain Cancer
Real World Study of Oxycodone/Naloxone Sustained-Release Tablets (Mimeixin) for Patients With Severe Cancer Pain
This study is a prospective, single-arm, multicenter, real-world study to evaluate effect of bowel function, analgesic effect, quality of life, and safety of Mimeixin® in Chinese patients with severe cancer pain.
- Trial name
- NCT06897917
- Testing
- Oxycodone Hydrochloride and Naloxone Hydrochloride Sustained-release Tablets
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Henan Cancer Hospital
Pain
A Study to Evaluate the Safety and Effectiveness of Fentanyl-TTS Compared to Weak Opioids in Patients With Moderate to Severe Chronic Cancer Pain Previously Treated With NSAIDS (Non-steroidal Anti-inflammatory Drugs).
To show, using the analgesic WHO scale, that fentanyl-TTS may be directly used for treating moderate to severe cancer pain in patients treated with NSAIDs, acetaminophen, or metamizole (first step drugs) avoiding the second step…
- Trial name
- NCT00576017
- Testing
- Fentanyl-TTS
- Volunteers
- 19 people
- Sponsor
- Janssen-Cilag, S.A.
Opioid-induced Constipation
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
This study will evaluate the safety and efficacy of Tegaserod in opioid-induced constipation in patients with non-cancer pain. Patients who enter this study PRIOR to the core study (CHTF919N2201) interim analysis receive the…
- Trial name
- NCT00414024
- Testing
- Tegaserod
- Where
- 6 sites in United States, China and 4 more
- Volunteers
- 11 people
- Sponsor
- Novartis
Pain, Unspecified Adult Solid Tumor, Protocol Specific
Valdecoxib in Treating Chronic Pain in Cancer Patients
RATIONALE: Valdecoxib may be effective in relieving chronic pain in cancer patients. It is not yet known if valdecoxib is effective in treating chronic pain.
- Trial name
- NCT00021996
- Testing
- valdecoxib
- Where
- 2 sites in United States
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Impact of Cognitive Impairment on Chronic Pain in Breast Cancer
Breast cancer treatments are associated with frequent and sometimes severe adverse effects that may significantly impair quality of life and lead to functional disability.
- Trial name
- Cactus (NCT07877376)
- Testing
- Evaluation of cognitive functions in patients with beast cancer
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Nadine ATTAL
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
This phase II trial studies whether psilocybin with psychotherapy is safe and if it works for improving chronic pain in cancer patients who require opioids to manage their pain.
- Trial name
- NCT06827054
- Testing
- Biospecimen Collection, Functional Magnetic Resonance Imaging, Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roswell Park Cancer Institute
Ankylosing Spondylitis, Sexual Dysfunction
Association of Erectile Dysfunction With Neuropathic Pain, Disease Activity, and Functional Status in Male Patients With Axial Spondyloarthritis: A Cross-Sectional Observational Study
tudy Description Definitions Use this module to describe the study protocol. Required § Required if Study Start Date is on or after January 18, 2017 [*] Conditionally required Brief Summary Use these resources to provide…
- Trial name
- NCT07453628
- Testing
- Anti-TNF agents, NSAIDs, No Treatment (Healthy Controls)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Altuğ Güner
Breast Carcinoma
Topical Cryotherapy in Reducing Pain in Patients With Chemotherapy Induced Peripheral Neuropathy or Paclitaxel Induced Acute Pain Syndrome
This randomized pilot clinical trial studies topical cryotherapy (cooling hands and feet with ice bags) in reducing pain in patients with chemotherapy induced peripheral neuropathy or paclitaxel induced acute pain syndrome.
- Trial name
- NCT02640053
- Testing
- Cryotherapy, Paclitaxel, Quality-of-Life Assessment
- Where
- 8 sites in United States
- Volunteers
- 46 people
- Sponsor
- Academic and Community Cancer Research United
Oral Mucositis, Quality of Life
Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy.
Head and Neck cancer patients receiving radiation therapy (with or without chemotherapy) suffer several oral complications, such as oral mucositis, which impairs quality of life of patients during radiotherapy and in the…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- NCT07739771
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Mucosa Innovations, S.L.
Cancer of Pancreas, Pain
Acupuncture for Pain Control in Patients With Inoperable Pancreatic Cancer
Pancreatic cancer is the sixth most common cause of cancer death in Hong Kong. Patients suffering from pancreatic cancer are associated with a poor prognosis and survival of less than one year is expected in inoperable tumours…
- Trial name
- NCT02333409
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 1 people
- Sponsor
- Chinese University of Hong Kong
Cancer, Cancer Pain
RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.
Pain, in neoplastic disease, is a symptom with severe negative impact on the quality of life of patients and a high incidence, with values around 70-90% in advanced and metastatic stages.
- Trial name
- CERP (NCT01809106)
- Testing
- Morphine, Fentanyl, Buprenorphine
- Where
- 9 sites in Italy
- Volunteers
- 518 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cancer Pain
Integrative Medicine for Pain in Patients With Advanced Cancer Trial (IMPACT)
The purpose of this study is to compare the long-term effectiveness of acupuncture versus massage in people living with advanced cancer.
- Trial name
- NCT04095234
- Testing
- Acupuncture, Massage
- Where
- 8 sites in United States
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Postoperative Pain
Combined Intrathecal Morphine and Dexmedetomidine Analgesia
The current study investigated the effect of adding dexmedetomidine to intrathecal morphine for postoperative analgesia in cancer patients undergoing major abdominal surgery.
- Trial name
- ITMandDEX (NCT02435537)
- Testing
- Dexmedetomidine (Precedex), Bupivacaine, Morphine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Neuropathic Pain in Cancer
Phase II Clinical Trial of NPC-06 in Patients With Neuropathic Pain in Cancer
The purpose of this trial is to investigate the efficiency of pain relief and the safety of NPC-06 for the neuropathic pain associated with cancer, in addition to explore the effective concentration of NPC-06.
- Trial name
- NCT03773055
- Testing
- NPC-06
- Where
- Japan
- Volunteers
- 7 people
- Sponsor
- Nobelpharma
Cancer
Impact of Therapeutic Osteopathy-hypnosis on Cancer Patients.
Osteopathy is recognized as a beneficial complementary approach for cancer patients. By addressing tissue mobility, circulation, and muscle tension, it helps improve physical comfort, reduce musculoskeletal pain, and foster…
- Trial name
- HYPOSTEO (NCT07860476)
- Testing
- Osteopathy, Hypnosis
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Institut Rafael