Clinical trials: Cancer Patients With Cancer Pain
Breast Cancer
Efficacy of Thoracic Paravertebral Block in the Reduction of Acute Post-surgical Pain in Patients With Breast Cancer
Surgical treatment of breast cancer is frequently associated with postoperative pain in the surgical area. Persistent pain after breast cancer management has considerable negative effects on the quality of life of survivors.
- Trial name
- NCT02609321
- Testing
- Thoracic Paravertebral Block, Surgical Wound Infiltration
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Instituto de Cancerología S.A.
Failed or Difficult Intubation, Adenoma
Water Method in Patients With Incomplete Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Conditions
- Failed or Difficult Intubation, Adenoma, Pain
- Trial name
- NCT01546246
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
Breast Cancer, Metastatic Cancer
Radiation Therapy in Treating Patients With Bone Metastases From Breast or Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which radiation therapy regimen is more effective for bone metastases.
- Conditions
- Breast Cancer, Metastatic Cancer, Pain, Prostate Cancer
- Trial name
- NCT00003162
- Testing
- pain therapy, radiation therapy
- Where
- 253 sites in United States, Canada
- Volunteers
- 949 people
- Sponsor
- Radiation Therapy Oncology Group
Metastatic Cancer, Pain
Stereotactic Body Radiation Therapy and Vertebroplasty in Treating Patients With Localized Spinal Metastasis
RATIONALE: Stereotactic body radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
- Conditions
- Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00855803
- Testing
- radiation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Texas Southwestern Medical Center
Cancer, Thrombosis
Pharmacokinetics of Low Molecular Weight Heparin in Cancer Patients
The purpose of the study is to determine the Pharmacokinetics of Low Molecular Weight Heparin (LMWH) in Cancer patients, and compare it to the Pharmacokinetics of LMWH in Patients without cancer.
- Conditions
- Cancer, Thrombosis, Angina Pectoris
- Trial name
- NCT00716898
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Shaare Zedek Medical Center
Pituitary, Pain, Postoperative
Postop Pain Management in Pituitary Tumour Patients
To assess the benefit of using an additional nerve block during minimally invasive pituitary surgery, to improve pain management after surgery.
- Trial name
- POPPY (NCT06353529)
- Testing
- Bupivacaine-Epinephrine 0.5%-1:200,000 Injectable Solution
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Hamilton Health Sciences Corporation
Plasma Cell Myeloma
Strength Training in Improving Pain and Quality of Life in Patients With Multiple Myeloma
This trial studies how well strength training works in improving bone health, pain, and quality of life in patients with multiple myeloma.
- Trial name
- NCT03793907
- Testing
- FitBit, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Roswell Park Cancer Institute
Cancer, Mucositis
Analgesic Effect in Children of Low-Dose Ketamine for Mucositis Treated by Patient-Controlled Analgesia With Morphine
Hypothesis : Low dose ketamine has an analgesic effect in children with mucositis treated by patient-controlled analgesia with morphine
- Trial name
- NCT00224692
- Testing
- Low dose ketamine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Cancer Pain, Pain Management
Effectiveness of Pain Management Interventions in Patients With Chronic Cancer Pain
The goal of this observational study is to observe the effectiveness of pain management strategies in patients with chronic cancer pain presenting to pain management clinic at Aga Khan University.
- Trial name
- NCT07395999
- Testing
- Pharmacological and pain Intervention procedure
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- Aga Khan University
Head and Neck Cancer, Oral Complications of Radiation Therapy
CD2 Lozenges in Preventing Acute Oral Mucositis in Patients With Head and Neck Cancer Receiving Radiotherapy and Chemotherapy
RATIONALE: Lactobacillus bevis CD2 lozenge may help prevent symptoms of mucositis, or mouth sores, in patients receiving radiation therapy and chemotherapy.
- Conditions
- Head and Neck Cancer, Oral Complications of Radiation Therapy, Pain, Weight Changes
- Trial name
- NCT01545687
- Testing
- Lactobacillus brevis CD2 lozenge
- Sponsor
- Alliance for Clinical Trials in Oncology
Pancreatic Cancer, Retroperitoneal Pain Syndrome
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain
Participants who are experiencing abdominal pain due to having cancer in their pancreas may be eligible for this research study. For this type of pain, doctors often recommend radiation therapy to help with the pain.
- Trial name
- NCT07117032
- Testing
- Simulation-free workflow, Celiac plexus SBRT
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center
Pain; Bone Neoplasms; Neoplasm Metastasis
A Study to Assess the Short Term Efficacy of Intravenous Ibandronate (Bondronat) in Participants With Metastatic Bone Pain Due to Breast Cancer
This study will assess the short term efficacy of ibandronate (6 mg intravenous [IV]) in participants with breast cancer and malignant bone disease, with moderate to severe pain.
- Trial name
- NCT02553707
- Testing
- Ibandronate
- Where
- 15 sites in Hungary
- Volunteers
- 182 people
- Sponsor
- Hoffmann-La Roche
Breast Cancer Patients With Chronic Pain After Surgery
Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study
This study aims to investigate the effect and influence of liposome bupivacaine anterior serrat plane block on postoperative chronic pain in breast cancer patients, evaluate the therapeutic effect of liposome bupivacaine in…
- Trial name
- NCT06427044
- Testing
- Anterior serratus block group
- Where
- China
- Volunteers
- 143 people
- Sponsor
- Lu Hua
Head and Neck Cancer
Study to Evaluate the Interest of Qutenza in Patients With Head and Neck Cancer in Remission and With Sequelae Neuropathic Pain.
This study aims to compare the analgesic activity of capsaicin patch 8% applications at 3 months interval each on the cervico-facial area versus a reference neuropathic treatment with amitriptyline in patients with head and neck…
- Trial name
- TEC-ORL (NCT04704453)
- Testing
- Capsaïcin patch (Qutenza®), Amitriptyline (Laroxyl®)
- Where
- 4 sites in France
- Volunteers
- 13 people
- Sponsor
- Institut Claudius Regaud
Pain
Evaluation of the Efficacy and Safety of Fentanyl Delivered by Adhesive Skin Patch in Out-Patients With Chronic Cancer Pain
The purpose of this study is to determine the safety and efficacy of pain control by fentanyl, administered via adhesive skin patches, at doses of 25 to 100 micrograms per hour in 80 out-patients with intense chronic cancer pain.
- Trial name
- NCT00236327
- Testing
- fentanyl
- Volunteers
- 34 people
- Sponsor
- Janssen Cilag S.A.S.
Pancreatic Cancer, Pain
Efficacy and Mechanisms of Acupuncture for Patients With Advanced Pancreatic Cancer Pain
This study compares the effect of acupuncture and placebo acupuncture on advanced pancreatic cancer pain and then investigates its potential mechanism of peripheral blood.
- Trial name
- NCT02510066
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Shanghai Cancer Hospital, China
Opioid-Induced Constipation (OIC)
Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
The purpose of this study is to evaluate the long-term safety and tolerability of NKTR-118 treatment of opioid-induced constipation (OIC) in patients with non-cancer-related pain.
- Trial name
- NCT01336205
- Testing
- NKTR-118, Usual care
- Where
- 169 sites in United States
- Volunteers
- 844 people
- Sponsor
- AstraZeneca
Pain; Cancer
An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Cancer Participants With Inadequately Controlled Pain by Non-Narcotic Analgesics
The purpose of this study is to evaluate the efficacy and safety of Transdermal Therapeutic System (TTS)-fentanyl D-Trans (transdermal patch containing a drug that is put on the skin so the drug will enter the body through the…
- Trial name
- NCT01060124
- Testing
- Fentanyl D-trans
- Volunteers
- 103 people
- Sponsor
- Janssen Korea, Ltd., Korea
Solid Tumors, Chemotherapy-induced Neutropenia
G-CSF-Related Bone Pain and Supportive Care Strategies in Patients With Solid Tumors
This prospective two-center observational cohort study evaluated G-CSF-related bone pain and multidimensional symptom burden in adults with solid tumors receiving chemotherapy and filgrastim prophylaxis.
- Trial name
- GCSF-PAIN (NCT07192770)
- Testing
- Filgrastim (G-CSF), Naproxen, Loratadine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Ankara Etlik City Hospital
Breast Cancer, Colorectal Cancer
Pain and Fatigue Management in Patients With Breast Cancer, Prostate Cancer, Colon Cancer, or Lung Cancer
RATIONALE: Collecting information over time about patients' and health care providers' understanding of pain and fatigue and providing education about pain and fatigue management may improve quality of life.
- Conditions
- Breast Cancer, Colorectal Cancer, Fatigue, Lung Cancer
- Trial name
- NCT00900835
- Testing
- educational intervention, questionnaire administration, study of socioeconomic and demographic variables
- Where
- United States
- Volunteers
- 470 people
- Sponsor
- City of Hope Medical Center