Clinical trials: Cancer Patients With Cancer Pain
Breakthrough Pain
Quality of Life Study Breakthrough Cancer Pain Treated in Medical Oncology Services (CAVIDIOM)
In cancer patients, pain is one of the most common symptoms. The range of reported prevalence of pain varies from 33% to 64% including different stages of cancer, during or after anticancer treatment.
- Trial name
- CAVIDIOM (NCT03435120)
- Testing
- No intervention
- Where
- 14 sites in Spain
- Volunteers
- 118 people
- Sponsor
- Angelini Farmacéutica
Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm
Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causing Pain, PREEMPT Trial
This phase III trial compares the effect of adding radiation therapy to usual treatment on the occurrence of bone-related complications in cancer patients with high-risk bone metastases that are not causing symptoms, such as pain…
- Trial name
- NCT06745024
- Testing
- Best Practice, Biospecimen Collection, Bone Metastases Treatment
- Where
- 626 sites in United States, Canada
- Volunteers
- 280 people
- Sponsor
- NRG Oncology
Multiple Myeloma, Adapted Physical Activity
Benefits of Adapted Physical Activity for Chronic Osteoarticular Pain in Patients With Multiple Myeloma
Pain is one of the most frequent symptoms leading patients to consult a doctor, particularly in rheumatology and cancerology. When it becomes chronic, pain is the cause of a major emotional and physical invasion, with harmful…
- Conditions
- Multiple Myeloma, Adapted Physical Activity, Chronic Pain
- Trial name
- ALGOMYELOMOV (NCT05548686)
- Testing
- adapted physical activity
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Prostate Cancer, Castration Resistant Prostate Cancer
Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100
This study will evaluate the effect of cabozantinib compared to prednisone on overall survival in men with previously treated metastatic castration-resistant prostate cancer with bone-dominant disease who have experienced disease…
- Conditions
- Prostate Cancer, Castration Resistant Prostate Cancer, Pain, Prostatic Neoplasms
- Trial name
- COMET-1 (NCT01605227)
- Testing
- cabozantinib, prednisone
- Where
- 264 sites in United States, Australia and 12 more
- Volunteers
- 1,028 people
- Sponsor
- Exelixis
Arthralgia, Breast Cancer
Testosterone in Treating Postmenopausal Patients With Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment
This randomized phase III trial studies testosterone to see how well it works compared to placebo in treating postmenopausal patients with arthralgia (joint pain) caused by anastrozole or letrozole.
- Conditions
- Arthralgia, Breast Cancer, Hot Flashes, Musculoskeletal Complications
- Trial name
- NCT01573442
- Testing
- testosterone
- Where
- 529 sites in United States, Puerto Rico
- Volunteers
- 227 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Upper Abdominal Cancer Pain, Pancreatic Cancer
Outcomes of Fluoroscopy-Guided Transdiscal Splanchnic Nerve Neurolysis for Upper Abdominal Cancer Pain.
The goal of this prospective study is to learn whether fluoroscopy-guided transdiscal splanchnic nerve neurolysis can safely reduce severe upper abdominal cancer pain in adults with pancreatic, gastric, or hepatobiliary cancer.
- Conditions
- Upper Abdominal Cancer Pain, Pancreatic Cancer, Gastric Cancer, Hepatobiliary Cancer
- Trial name
- NCT07825870
- Testing
- Chemical Neurolysis
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Sahiwal medical college sahiwal
Moderate to Severe Acute Non-Cancer Pain
A Safety and Effectiveness Study of Immediate Release Tapentadol Hydrochloride Among Filipino Patients With Moderate to Severe Acute Non-Cancer Pain
The purpose of this study is to evaluate the safety and effectiveness of immediate release tapentadol hydrochloride for the relief of moderate to severe acute non-cancer pain among Filipino patients.
- Trial name
- NCT01719601
- Testing
- No intervention
- Sponsor
- Janssen Pharmaceutica
Pain, Unspecified Adult Solid Tumor, Protocol Specific
Oxycodone or Standard Pain Therapy in Treating Patients With Cancer Pain
RATIONALE: Oxycodone helps lessen pain caused by cancer and may improve quality of life. It is not yet known whether oxycodone works better and is more cost effective than standard therapy in treating patients with cancer pain.
- Trial name
- NCT00378937
- Testing
- acetaminophen, codeine phosphate, dextropropoxyphene hydrochloride
- Volunteers
- 30 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Pain
The Efficacy of Pain Management With Self-reporting Pain Monitoring System in Cancer Patient
To compare the pain scales between clinician evaluated and reported with wearable device by patients.
- Trial name
- pain (NCT03117075)
- Testing
- using device for scoring pain scale, named "ANAPA®"
- Where
- 2 sites in South Korea
- Volunteers
- 68 people
- Sponsor
- DERSHENG SUN
Cancer
The Effect of Sujok Therapy on Cancer Symptoms
The aim of this study is to determine the effect of Sujok therapy on Pain, Fatigue, Insomnia, Nausea and Vomiting experienced by patients with gastrointestinal system cancer.
- Trial name
- NCT05265754
- Testing
- sujok therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Ataturk University
Metastatic Cancer, Pain
Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer
RATIONALE: Morphine may reduce pain in patients who have undergone radiofrequency ablation to remove bone metastases. PURPOSE: This phase II trial is studying how well morphine works after radiofrequency ablation of painful bone…
- Conditions
- Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- MEDOR (NCT00712712)
- Testing
- Acetaminophen, Morphine Sulfate, Questionnaire administration
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Institut Bergonié
Advanced Cancers
Sublingual Fentanyl for the Management of Breakthrough Pain
The goal of this clinical research study is to learn if an investigational dose of fentanyl sublingual spray (FSS) can help to control pain in patients with advanced cancer when given in an outpatient and inpatient setting.
- Trial name
- NCT02514252
- Testing
- Fentanyl Sublingual Spray (FSS), Questionnaires, Mental Ability Tests
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
Advanced Cancer, Pancreatic Cancer
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain
This is a prospective, single-arm, pilot feasibility clinical trial designed to evaluate the feasibility and safety of a simulation-free adaptive radiotherapy workflow to enable single-session celiac plexus SBRT planning and…
- Trial name
- Celiac SRS (NCT07636382)
- Testing
- Treatment plan
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
Pain Cancer
Effectiveness of Percutaneous Neuromodulation vs Pharmacological Treatment in Cancer Patients With Anterior Knee Pain
the goal of this clinical trial is to compare in cancer patients: Is ultrasound-guided percutaneous neuromodulation useful for Anterior Knee Pain relief in cancer patients? Participants will receive treatments of…
- Trial name
- NCT06240390
- Testing
- Ultrasound-guided percutaneous neuromodulation (NMP), pharmacological treatment by Opioids
- Where
- Spain
- Sponsor
- Universidad Europea de Canarias
Refractory Cancer Pain, Intrathecal Analgesia
Intrathecal Analgesia Effects on Cancer Patients Discomfort Symptoms
Intrathecal analgesia is used in refractory cancer pain because of drug sides effects or intractable pain. The aim of this approach is to improve pain management, and also to improve patient comfort.
- Trial name
- IT-ESAS (NCT04491123)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Malignant Neoplasms of Digestive Organs, Malignant Neoplasms of Female Genital Organs
Neuromuscular Blockade on Shoulder Pain of Elderly
Insufflation pressure (IP) is the creation of a pressure barrier of air/gas within the abdomen to allow the surgeon more space to work during abdominal surgery.
- Conditions
- Malignant Neoplasms of Digestive Organs, Malignant Neoplasms of Female Genital Organs, Malignant Neoplasms of Male Genital Organs, Malignant Neoplasms of Urinary Tract
- Trial name
- NCT03210376
- Testing
- Deep Neuromuscular Blockade (NMB), Moderate Neuromuscular Blockade (NMB), Sugammadex
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Castrate-Resistant Prostate Cancer, Hormone Refractory Prostate Cancer
A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
The purpose of this study is to determine if the addition of study drug (custirsen) can provide durable pain palliation for castrate resistant prostate cancer patients receiving docetaxel retreatment or cabazitaxel as a second…
- Trial name
- NCT01083615
- Testing
- custirsen sodium, isotonic, 0.9% sodium chloride, docetaxel
- Where
- 33 sites in United States, Canada and 3 more
- Volunteers
- 14 people
- Sponsor
- Achieve Life Sciences
Opioid, Moderate Cancer Pain, Transdermal Fentanyl, 12.5ug/h, Opioid-naive
Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer Pain
Opioid is recommended for moderate cancer pain in WHO 3-step analgesic ladder. Transdermal administration of the strong opioid fentanyl was originally developed for patients unable to swallow analgesics because of malignancies in…
- Trial name
- NCT04533243
- Testing
- 2.5ug/h transdermal fentanyl, Oral immediate-released morphine
- Volunteers
- 209 people
- Sponsor
- Fujian Cancer Hospital
Postoperative Pain, Opioid Use
Conditioned Open-label Placebo (COLP) for Peri-operative Pain Management in Patients With Head and Neck Cancer
The opioid epidemic is a considerable problem in the United States, and prescription opioids significantly contribute to the epidemic.
- Trial name
- NCT04973748
- Testing
- Surveys about pain, opioid use and depression symptoms
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Johns Hopkins University
Advanced Cancer
The Effect of Donepezil on Sedation and Other Symptoms
Primary Objective: 1. To determine the effectiveness of donepezil as compared to placebo for the management of opiate-induced sedation/drowsiness in patients with stable cancer pain Secondary Objectives: 1.
- Trial name
- NCT00352664
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- M.D. Anderson Cancer Center