Clinical trials: Cancer Pelvis
Neoplasm - Soft Tissue Pelvis Malignant Secondary, Malignant Neoplasm of Stomach
Adaptive Radiation for Abdominopelvic Metastases
Single arm Phase I trial of adaptive stereotactic body radiation (SBRT) for abdominopelvic metastases. Adaptive SBRT will allow for escalation of the prescription dose and target coverage while maintaining grade 3+ toxicity no…
- Trial name
- NCT05880667
- Testing
- Adaptive Stereotactic Body Radiation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Fox Chase Cancer Center
Gynecologic Cancer, Venous Thromboembolism
Oral Apixaban (Eliquis) Versus Enoxaparin (Lovenox) for Thromboprophylaxis in Women With Suspected Pelvic Malignancy
The study will evaluate the incidence of major bleeding (including clinically relevant non-major (CRNM) bleeding) events in women undergoing surgery for gynecologic cancer with apixaban 2.5 mg twice a day (BID) compared to…
- Trial name
- NCT02366871
- Testing
- Oral apixaban, Subcutaneous enoxaparin
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Colorado, Denver
Pelvic Muscle Strength and Function
Assessment of PFM Strength and Function After Radiotherapy Treatment in Women With Pelvic Cancers
Assessment the effect of radiotherapy treatment on pelvic floor muscles in women with pelvic cancers
- Trial name
- PFM (NCT06820801)
- Testing
- pelvic floor muscles strength and function
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Prostate Cancer
Radiation Therapy, Docetaxel, and Hormone Therapy in High-Risk Locally Advanced Metastasized Prostate Cancer
RATIONALE: Specialized radiation therapy that delivers a high- dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
- Trial name
- NCT00482807
- Testing
- bicalutamide, docetaxel, goserelin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Nebraska
Lymphocele, Endometrial Cancer
Application of Tachosil During Lymphadenectomy
The prevention of lymphoceles was assessed using collagen patch coated with the human coagulation factors (TachoSil, Nycomed International Management GmbH, Zurich, Switzerland; NCT Number ICMJE NCT01192022; Other Study ID Numbers…
- Conditions
- Lymphocele, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT03752606
- Testing
- TACHOSIL GROUP
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lublin
Rectum Neoplasms
Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients
TME (Total mesorectum excision) is the golden standard of radical resection for mid-low rectal cancer. However, the damage of pelvic autonomic nerve following with TME principle will lead to high incidence of urinary and sexual…
- Trial name
- NCT02164136
- Testing
- L-PANP-TME, O-PANP-TME
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Prostate Cancer
Duration of Androgen Blockade Combined With Pelvic Irradiation in Prostate Cancers
The objective of this study is to use as a reference the 36-month duration of hormonal therapy according to the European Organization for Research of the Treatment of Cancer (EORTC protocol 22863) : namely one-month of total…
- Trial name
- PCS IV (NCT00223171)
- Testing
- Androgen blockade + radiation therapy
- Where
- Canada
- Volunteers
- 630 people
- Sponsor
- Université de Sherbrooke
Lymphoma, Small Intestine Cancer
Irinotecan in Treating Patients With Solid Tumors or Lymphoma Who Have Abnormal Liver or Kidney Function or Who Have Received Radiation Therapy to the Pelvis
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Irinotecan may be effective in treating patients with abnormal liver or kidney function or who have received…
- Conditions
- Lymphoma, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00003368
- Testing
- irinotecan hydrochloride
- Where
- 45 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Surgery
A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
The purpose of this study is to find out how many participants are interested in a surgical preventive procedure after watching an educational video.
- Trial name
- NCT06312124
- Testing
- Educational Module, Salpingectomy
- Where
- 10 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
High Risk Prostate Cancer
Surgical Treatment With or Without Apalutamide in Subjects With High Risk Prostate Cancer Who Are Candidates for Radical Prostatectomy and Staged as Oligometastatic With PSMA-PET
This is a phase 2, open-label, randomized study of adjuvant treatment in subjects with high-risk prostate cancer who are candidates for RP with PLND based on M0 status at conventional imaging, but staged as oligometastatic with…
- Trial name
- STAPLE (NCT06758882)
- Testing
- Apalutamide, Androgen receptor (AR) inhibitor
- Where
- Italy
- Volunteers
- 94 people
- Sponsor
- Marco Oderda
Coxarthrosis; Primary, Coxarthrosis; Secondary
Is the Dynamic of the Pelvic Bone Altered After a Total Hip Replacement ?
Total hip replacement is one of the most common surgical procedure in France. In 2010, an estimated 147 513 total hip procedures were performed. This number is constantly increasing.
- Trial name
- DYPAMAT (NCT04587440)
- Testing
- Pelvic inclination measurement
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Pelvic Tumor, Thoracic Tumor
Pelvic Cancer Registry for Online Adapted Radiotherapy
This prospective registry-based trial will include patients with pelvic or thoracic tumors with an indication for radiotherapy treated with oART or IGRT.
- Trial name
- PRoART (NCT06185062)
- Where
- Germany
- Volunteers
- 846 people
- Sponsor
- University Medical Center Goettingen
Bone Neoplasm, Metastatic Malignant Neoplasm in the Bone
Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root Involvement
This clinical trial tests how well monitoring the sacral reflexes during surgery (intraoperatively) works to predict the post operative function for patients undergoing removal of the lowest part of the spine (sacrectomy) for…
- Trial name
- NCT07707024
- Testing
- Intraoperative Nerve Monitoring, Surgical Procedure, Survey Administration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- City of Hope Medical Center
Metastatic Solid Tumor, Recurrent Solid Tumor
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
The purpose of this study is to find out whether the study drug, LY4052031, is safe, tolerable and effective in participants with advanced, or metastatic solid tumors including urothelial cancer.
- Conditions
- Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm
- Trial name
- NEXUS-01 (NCT06465069)
- Testing
- LY4052031, Pembrolizumab
- Where
- 39 sites in United States, Australia and 6 more
- Volunteers
- 460 people
- Sponsor
- Eli Lilly and Company
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Protection of Autonomic Nervous System During Lower Spine Surgical Procedures: A Safety and Feasibility Study
A safety and feasibility study of free-run and stimulated corporal electromyography (EMG) to assess autonomic neural function during spinal and/or pelvic surgery in women and men.
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Stenosis
- Trial name
- NCT02873182
- Testing
- Autonomic nervous system monitoring
- Volunteers
- 20 people
- Sponsor
- Stanley Skinner
Localized Prostate Carcinoma, Oligometastatic Prostate Carcinoma
Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer
This clinical trial evaluates the use of an imaging scan (18F-rhPSMA-7.3 positron emission tomography [PET]/magnetic resonance imaging [MRI]) for identifying patients who are at risk of having their disease spread to the lymph…
- Conditions
- Localized Prostate Carcinoma, Oligometastatic Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
- Trial name
- NCT06389786
- Testing
- Bilateral Pelvic Lymph Node Dissection, Biospecimen Collection, Bone Scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Incisional Hernia, Pelvic Cancer
Trial of Collagen Mesh for Prevention of Ventral Hernia After Surgery for Advanced Pelvic Cancer
The aim of the present project is to investigate whether use of biological mesh at the donor site of the rotation flap in closure of the abdominal wall reduce the frequency of incisional hernia formation compared to the usual…
- Trial name
- VRAM (NCT00647569)
- Testing
- Mesh repair, Conventional facial closure
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Rectal Neoplasms
Exercise Training for Rectal Cancer Patients
Cancer treatments often cause acute toxicity during treatment, and late toxicity after treatments have ended. Bowel dysfunctions, incontinence (anal and urinary) and dysfunction are late side effects associated with cancer…
- Trial name
- NCT02538913
- Testing
- Exercise training, Usual care
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Norwegian University of Science and Technology
Endometrial Carcinoma, Lymphadenectomy
The Clinical Significance of Sentinel Lymph Node Imaging Combined With Imaging Examination in Pelvic and Peritoneal Lymphadenectomy for Endometrial Carcinoma
The aim of this prospective cohort study is to explore the clinical significance of sentinel lymph node imaging combined imaging examination evaluation in pelvic and peritoneal lymphadenectomy for endometrial carcinoma management.
- Trial name
- NCT03877627
- Testing
- Pelvic and Peritoneal Lymphadenectomy
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cervival Cancer
Hypofractionated Chemoradiotherapy for Cervical Cancer
The goal of this clinical trial is to evaluate whether hypofractionated whole pelvic or extended-field concurrent chemoradiotherapy can improve treatment access and efficiency while potentially providing superior oncologic…
- Trial name
- HYPOCx (NCT07709650)
- Testing
- Hypofractionated Chemoradiotherapy, Conventional Chemoradiotherapy, Concurrent chemotherapy
- Where
- Thailand
- Volunteers
- 250 people
- Sponsor
- Mahidol University