Clinical trials: Cancer Uterus Cervix
Carcinoma, Neoplasia; Intraepithelial, Cervix
Evaluation Glizigen® and Ocoxin®-Viusid® in High-grade Cervical Intraepithelial Lesions
Phase II clinical trial, monocentric, not controlled, in patients with high grade cervical intraepithelial lesions. A total of 62 patients with a diagnosis of CIN II, III or carcinoma in situ will be included.
- Conditions
- Carcinoma, Neoplasia; Intraepithelial, Cervix, Glandular Neoplasms, Epithelial Neoplasm
- Trial name
- NCT03549273
- Testing
- Glizigen® + Ocoxin-Viusid®
- Where
- Cuba
- Volunteers
- 62 people
- Sponsor
- Catalysis SL
Cervical Dysplasia
Endocervical Evaluation With the Curette Versus Cytobrush for the Diagnosis of Dysplasia of the Uterine Cervix
OBJECTIVE: to compare endocervical brushing with endocervical curettage with respect to diagnostic and patient discomfort. METHOD: women referred to colposcopy because of abnormal Papanicolaou tests will be randomized to…
- Trial name
- NCT01435590
- Testing
- Curette v/s endocervical brush
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Uterine Cervical Dysplasia, Uterine Cervix Cancer
The SAFE Study: Satisfaction and Adherence to Follow-Up With Colposcopy Exams
This study is intended to improve the patient experience of communication of colposcopy results and follow-up recommendations to patients.
- Trial name
- NCT03296566
- Testing
- Patient Liaison
- Where
- Canada
- Volunteers
- 297 people
- Sponsor
- University of British Columbia
Uterine Cervical Neoplasms
An Exploratory Study on the Efficacy and Safety of Enlonstobart Combined With Concurrent Radiotherapy and Chemotherapy Following Induction Therapy With Enlonstobart Plus Chemotherapy in Patients With Locally Advanced Cervical Cancer.
The objective of this clinical trial is to investigate the efficacy and safety of Enlonstobart combined with concurrent chemoradiotherapy following induction chemotherapy for locally advanced cervical cancer.
- Trial name
- NCT07776821
- Testing
- Enlonstobart combined with chemotherapy for induction therapy followed by concurrent radiother
- Where
- 2 sites in China
- Volunteers
- 31 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Cervix Cancer
Image-guided Adaptive Radiotherapy for Cervix Cancer: Patient Image Acquisition
Within this study patient data are collected from different imaging and motion monitoring devices that will be used to develop and test strategies for image-guided adaptive radiotherapy in cervix cancer patients.
- Trial name
- NCT00571415
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Virginia Commonwealth University
Cervical Intraepithelial Neoplasia, Uterine Neoplasms
A Trial for Patients With Advanced/Recurrent Cervical Cancer
This phase II trial is studying the antitumor activity of single agent pemetrexed 900mg/m2 IV over 10 minutes in patients with recurrent cervical cancer.
- Conditions
- Cervical Intraepithelial Neoplasia, Uterine Neoplasms, Genital Neoplasms, Female
- Trial name
- NCT00190983
- Testing
- Pemetrexed
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Eli Lilly and Company
Cervix Cancer
Alendronate to Reduce Pelvic Insufficiency Fractures in Cervical Cancer Patients Undergoing Chemoradiation
Primary Objective Proof of concept: To evaluate the efficacy of alendronate in preventing pelvic insufficiency fractures (PIFs) in cervical cancer patients treated with chemo-radiotherapy over the short and long term.
- Trial name
- NCT07245381
- Testing
- Alendronate 70mg weekly
- Volunteers
- 65 people
- Sponsor
- Dr. Itay GoorAryeh
Cervical Cancer
Topotecan in Treating Women With Persistent or Recurrent Cervical Cancer
RATIONALE: Drugs used in chemotherapy, such as topotecan, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00087126
- Testing
- topotecan hydrochloride
- Where
- 27 sites in United States
- Volunteers
- 27 people
- Sponsor
- Gynecologic Oncology Group
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Paclitaxel, Cisplatin, and Veliparib in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
This phase I clinical trial studies the side effects and best dose of veliparib when given together with paclitaxel and cisplatin and to see how well they work in treating patients with cervical cancer that has spread to other…
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Recurrent Cervical Carcinoma
- Trial name
- NCT01281852
- Testing
- Cisplatin, Laboratory Biomarker Analysis, Paclitaxel
- Where
- 25 sites in United States
- Volunteers
- 37 people
- Sponsor
- National Cancer Institute (NCI)
Cervical Cancer, Anemia
A Study to Evaluate the Impact of Maintaining Hemoglobin Levels in Anemic Patients With Carcinoma of the Cervix
The purpose of this study is to assess the feasibility, safety and short term effects on health related quality of life, of maintaining hemoglobin from 120 to 130 g/L versus from 100 to 110 g/L, with red cell concentrate (RCC)…
- Trial name
- HOSTT (NCT00921635)
- Testing
- Blood transfusion
- Volunteers
- 2 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Cervical Cancer
Predicting Outcome in Cervix Carcinoma: a Prospective Study
The main aim is to validate and improve the predictive model for survival and toxicity in patients with cervical cancer through multicentric prospective data collection.
- Trial name
- POCER (NCT01825005)
- Where
- 2 sites in Netherlands, South Africa
- Volunteers
- 423 people
- Sponsor
- Maastricht Radiation Oncology
Cervix Cancer
CRP on Radiobiological and Clinical Studies on Viral-Induced Cancer's Response to Radiotherapy
The purpose of this trial is to study clinical effects of two/four high dose rate (HDR) brachytherapy applications and teletherapy with or without weekly cisplatin in cervix cancer.
- Trial name
- NCT00122772
- Testing
- Radiotherapy, Radiotherapy/Cisplatin
- Where
- 11 sites in Austria, Brazil and 9 more
- Volunteers
- 601 people
- Sponsor
- International Atomic Energy Agency
Cervical Cancer
A Pilot Study Using Magnetic Resonance (MR) to Assess Cervix Motion During Radiotherapy Treatment.
The standard treatment for locally advanced cervical cancer is concurrent chemo-radiotherapy. This treatment is associated with long term side effects in around half of patients with up to 10% suffering from grade 3-4 toxicity.
- Trial name
- MR Cervix (NCT03101306)
- Testing
- MR scans
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- The Christie NHS Foundation Trust
Neoplasms, Uterine Cervix, Cervical Cancer
Cross-sectional Study on Human Papillomavirus Type Distribution in Adult Women Diagnosed With Cervical Cancer
The current study will elucidate the human papillomavirus type distribution in a population of women diagnosed with cervical high grade pre-cancerous lesions and invasive cervical cancer in Sri Lanka.
- Trial name
- NCT01221987
- Testing
- Cervical sampling, Data collection
- Volunteers
- 40 people
- Sponsor
- GlaxoSmithKline
Cervical Cancer, Precancerous Condition
Fluorescence and Reflectance Spectroscopy During Colposcopy in Detecting Cervical Intraepithelial Neoplasia and Dysplasia in Healthy Participants With a History of Normal Pap Smears
RATIONALE: New diagnostic procedures such as fluorescence and reflectance spectroscopy (shining light on tissue and measuring patterns of light reflected) may improve the ability to noninvasively detect cervical intraepithelial…
- Trial name
- NCT00084903
- Testing
- Colposcopic biopsy, Light-Scattering Spectroscopy
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,070 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Melanoma
Study of GSK2132231A Antigen-Specific Cancer Immunotherapeutic in Patients With Inoperable Metastatic Cutaneous Melanoma
The clinical objective of this clinical trial is to examine the clinical activity in terms of tumor response and time to treatment failure of the immunotherapeutic product GSK2132231A when given to patients with unresectable and…
- Trial name
- NCT00896480
- Testing
- Immunotherapeutic GSK2132231A
- Where
- 8 sites in Belgium, France
- Volunteers
- 24 people
- Sponsor
- GlaxoSmithKline
Cervix Carcinoma
Radiotherapy + Metronidazole vs Radiotherapy Alone In Improving Treatment Outcomes in Advanced Cervical Cancer in Uganda
The objective of the study was to determine whether there was a difference in the effectiveness of Radiotherapy alone compared with Radiotherapy plus Metronidazole in the treatment of women with advanced cancer of the cervix in…
- Trial name
- NCT01937650
- Testing
- Radiotherapy plus metronidazole
- Volunteers
- 38 people
- Sponsor
- Makerere University
Cervix Neoplasm, Cervix, Dysplasia
Thermal Artifact in Patients Undergoing Conization: A Clinical Study
Cervical transformation zone excision is commonly used in the diagnosis and treatment of cervical intraepithelial neoplasia. Thermal artifacts can negatively affect histopathological evaluation.
- Trial name
- NCT07372248
- Testing
- Conization with Electrosurgery diffferent power settings
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Saglik Bilimleri Universitesi
Melanoma, Breast Cancer
Survival Monitoring in Russian Cancer Registries
This study aims to establish a holistic framework for continuous cancer survival surveillance in Russian regions with high-quality population-based cancer registry data.
- Conditions
- Melanoma, Breast Cancer, Oncology, Colon Cancer
- Trial name
- SURVIMON (NCT06043947)
- Where
- Russia
- Volunteers
- 100,000 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Cancer of Head and Neck, Cancer of Cervix
Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer
This research study is studying a therapeutic vaccine, named DPX-E7, as a possible treatment for Human Papilloma Virus or HPV related head and neck, cervical or anal cancer (positive for HLA-A*02).
- Conditions
- Cancer of Head and Neck, Cancer of Cervix, Cancer of Anus
- Trial name
- NCT02865135
- Testing
- DPX-E7 vaccine, Cyclophosphamide
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dana-Farber Cancer Institute