Clinical trials: Cancer Uterus Cervix
Cervix Cancer
Efficacy Study of Weekly Topotecan With Cisplatin in Advanced Stage or Recurrent Cervical Cancer
The purpose of this study is to determine the maximum tolerated dose (MTD) of topotecan when given weekly with cisplatin in patients with persistent, recurrent, or advanced stage cervical cancer.
- Trial name
- NCT00322920
- Testing
- Topotecan, Cisplatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Cancer Uterus Cervix
Respiration After Robot Assisted Laparoscopic Hysterectomy
The study will investigate how respiratory function is affected by robot-assisted surgery. Previous studies have investigated the impact after open and laparoscopic surgery, but there are no studies yet after robot-assisted…
- Trial name
- REHYR (NCT06806280)
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Cervix Neoplasm
Low-Dose Taxotere® (Docetaxel) With Concurrent Radiotherapy For Localized, Inoperable Carcinoma Of The Uterine Cervix
The purpose of this study is to find out how effectively cervix cancer is controlled when radiation is combined with low-dose chemotherapy (Taxotere) .
- Trial name
- NCT00178269
- Testing
- docetaxel, Radiation Therapy
- Where
- United States
- Sponsor
- University of Rochester
Uterine Cancer, Cervix Uteri Nos
A Global Assessment of Medical, Emotional and Reproductive Concerns in Gestational Trophoblastic Disease Survivors
The purpose of this study is to collect information on the effects of treatment for gestational trophoblastic disease (GTD). We plan to use the findings from this study to better understand GTD survivors' health and quality of…
- Conditions
- Uterine Cancer, Cervix Uteri Nos, Gestational Trophoblastic Disease
- Trial name
- NCT00706875
- Testing
- questionnaire
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer of the Uterine Cervix
Diagnostic Performance of 18F-FDG-PET and Diffusion-weighted MRI in the Assessment of Stage IB to IIB2 Cervical Squamous-cell Carcinoma Response to Concomitant Radiochemotherapy and Brachytherapy
Rationale: The benefit-risk ratio of surgery following concomitant radiochemotherapy and brachytherapy remains to be defined in cervical squamous-cell carcinoma (SCC) treatment.
- Trial name
- ERRICC (NCT01663753)
- Testing
- 18F-FDG-PET
- Where
- 24 sites in France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
CIN, Cancer of Cervix
Histopathological Findings in Symptomatizing Patients After Supracervical Hysterectomy
Supracervical hysterectomy is widely common and had many complications either immediate or delayed. In these patients bleeding, infection, chronic pelvic pain are common.
- Conditions
- CIN, Cancer of Cervix, Cervicitis
- Trial name
- HSTH (NCT04809727)
- Testing
- Cervical biopsy
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Tanta University
Cervical Cancer
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
- Trial name
- ROCC (NCT04831580)
- Testing
- da Vinci, open surgery
- Where
- 156 sites in United States, Brazil and 2 more
- Volunteers
- 840 people
- Sponsor
- GOG Foundation
Cervical Intraepithelial Neoplasia, Squamous Intraepithelial Lesions of the Cervix
Conservative Management of HSIL in Patients With Future Pregnancy Aspiration
Conservative management of high-grade squamous intraepithelial lesions (HSILs) seems safe and justified in young women (<30 years), but evidence is insufficient on whether it is also advisable for older women.
- Conditions
- Cervical Intraepithelial Neoplasia, Squamous Intraepithelial Lesions of the Cervix, Uterine Cervical Dysplasia
- Trial name
- NCT04783805
- Testing
- Conservative management with regular follow-up, Conization
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cervix Cancer, HIV Infections
Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in Women Living With HIV
This Clinical Trials Network for Human Immunodeficiency Virus (HIV)-Associated Cervical Cancer Screening and Treatment Optimization (CASCADE)-3001-B trial aims to assess how the introduction of a…
- Conditions
- Cervix Cancer, HIV Infections, HPV Infection
- Trial name
- C-3001B-P-CS7 (NCT07624123)
- Testing
- Model 1- Screening in Clinic Only, Model 2 - Screening in Clinic and Community
- Where
- Zimbabwe
- Volunteers
- 17,734 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cervix Neoplasms
Healing Touch and Relaxation Therapies in Cervical Cancer Patients
The purpose of this study is to evaluate the effects of healing touch and relaxation therapy on cervical cancer patients undergoing chemotherapy and radiation treatment.
- Trial name
- NCT00084123
- Testing
- Healing Touch Therapy, Relaxation Therapy, Standard Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cervix Cancer
Prevalence of Abnormal Pap Smear
This study aims to evaluate prevalence of abnormal Pap smear among sexually active women of reproductive age attending sohag university hospital outpatient clinic.
- Trial name
- NCT06641531
- Testing
- Screening pap smear test
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cervical Cancer
Use of Social Networking to Survey Women With Small and Large Cell Carcinomas of the Cervix
Objectives: Primary: 1. To assess the feasibility of using social networking groups to survey patients with rare cancers. Secondary:1.
- Trial name
- NCT01606293
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Uterine Cervical Neoplasms
A Chinese Cohort of Cervical Large Cell Neuroendocrine Carcinoma
Cervical large cell neuroendocrine carcinoma (LCNEC) exhibits highly aggressive biological behavior, including strong invasiveness, a high propensity for metastasis, drug resistance, and poor prognosis, necessitating heightened…
- Trial name
- CN-CLCNEC (NCT07240753)
- Testing
- Postoperative pathological examination confirmed cervical large cell neuroendocrine carcinoma.
- Volunteers
- 200 people
- Sponsor
- Lili
Cervical Cancer
Radiation Therapy, Paclitaxel, and Cisplatin in Treating Patients With Cancer of the Cervix
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Paclitaxel and cisplatin may increase the effectiveness of radiation therapy by making the tumor cells more sensitive to the radiation.
- Trial name
- NCT00003377
- Testing
- cisplatin, paclitaxel, brachytherapy
- Where
- 13 sites in United States
- Volunteers
- 29 people
- Sponsor
- Gynecologic Oncology Group
Cervix Cancer, Cervix Neoplasm
Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya
To investigate the use of self-administered artesunate vaginal pessaries as treatment for cervical precancer in low and middle-income countries (LMIC).
- Conditions
- Cervix Cancer, Cervix Neoplasm, Precancerous Conditions, Cervical Precancer
- Trial name
- NCT06165614
- Testing
- Artesunate pessary, Colposcopy
- Where
- Kenya
- Volunteers
- 17 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Locally Advanced Cervical Cancer
A Study of mTOR Inhibitor Everolimus (RAD001) in Association With Cisplatin and Radiotherapy for Locally Advanced Cervix Cancer
The cervix cancer is the second malignant neoplasia more common between women. The combined treatment involving chemotherapy and radiotherapy was defined as the standard.
- Trial name
- PHOENIX I (NCT01217177)
- Testing
- everolimus
- Where
- 2 sites in Brazil
- Volunteers
- 14 people
- Sponsor
- Novartis Pharmaceuticals
Cervical Cancer, Precancerous Condition
Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix, Cervical Intraepithelial Neoplasia, or Early Invasive Cervical Cancer
RATIONALE: Studying samples of tissue from patients with or without cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00900081
- Testing
- immunohistochemistry staining method, laboratory biomarker analysis, medical chart review
- Sponsor
- Wake Forest University Health Sciences
Cancer, Breast, Cancer, Metastatic
Guided Imagery & Music in Cancer
This is an RCT pilot study to explore the potential effects of the Guided Imagery \& Music method for women with breast or gynecologic cancer, during active treatment.
- Conditions
- Cancer, Breast, Cancer, Metastatic, Cancer Ovaries, Cancer Uterus Cervix
- Trial name
- NCT03936075
- Testing
- the Guided Imagery and Music method, standard care and verbal counselling
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Aalborg University
Cancer of Unknown Origin, Cancer Refractory
Genomic Testing and Resulting Medical Decisions
There is no evidence available about which molecular profiling methods are currently used for cancer patients in Austrian clinical practice.
- Conditions
- Cancer of Unknown Origin, Cancer Refractory, Cancer of Stomach, Cancer Head Neck
- Trial name
- NCT03301493
- Testing
- Genomic testing
- Where
- 11 sites in Austria
- Volunteers
- 1,500 people
- Sponsor
- Arbeitsgemeinschaft medikamentoese Tumortherapie
Locally Advanced Cervical Carcinoma, Locally Advanced Cervical Cancer
MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial
This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-related data (imaging, dosimetry, clinical) before, during, and after…
- Conditions
- Locally Advanced Cervical Carcinoma, Locally Advanced Cervical Cancer, Locally Advanced Pancreas Cancer, Locally Advanced Pancreatic Carcinoma
- Trial name
- METEOR-CRATR (NCT05975593)
- Testing
- Tumor collection via biopsy, Blood collection, Diffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine