Clinical trials: Cancer of Pelvis
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Neoplasms, Adenocarcinoma
Beyond TME Origins
All patients with recurrent colorectal cancer in the pelvis are eligible. The original primary tumour staging scans and resected surgical specimen needs to be available.
- Conditions
- Neoplasms, Adenocarcinoma, Carcinoma
- Trial name
- NCT02292641
- Testing
- New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pelvic exenterative surgery
- Where
- 4 sites in Norway, United Kingdom
- Volunteers
- 383 people
- Sponsor
- Imperial College London
Epithelial Ovarian Cancer
Exploration of DNA Methylation as a Marker for Early Detection of High Grade Serous Epithelial Ovarian Cancer
The purpose of this study is to determine if there are markers in plasma that can be used to develop a diagnostic panel for early detection and diagnosis of high grade serous epithelial ovarian cancer.
- Trial name
- NCT03622385
- Testing
- DNA Methylation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Bladder Cancer, Transitional Cell Carcinoma
Lymph Node Processing Protocol for Radical Cystectomy and Pelvic Lymph Node Dissection in Bladder Cancer
When the bladder is removed for bladder cancer, pelvic lymph nodes (LN) are also removed. While the anatomic extent of this LN dissection is critical, the investigators often use the number of LN removed as a measure of the…
- Trial name
- NCT01395225
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Gemcitabine Hydrochloride, Cisplatin, and Sunitinib Malate as First-Line Therapy in Treating Patients With Locally Advanced And/or Metastatic Transitional Cell Carcinoma of the Urothelium (SUCCINCT)
RATIONALE: Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT01089088
- Testing
- cisplatin, gemcitabine hydrochloride, sunitinib malate
- Where
- 16 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Cardiff University
Constipation, Childhood ALL
PTNS and PFR in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood, affecting an estimated 20% of children globally. At present, the treatment of children's constipation is full of challenges, and treatment methods are diverse.
- Conditions
- Constipation, Childhood ALL, Pelvic Floor Disorders
- Trial name
- NCT05059756
- Testing
- PTNS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Evaluation of the Prevalence of Pelvic Static Disorders in Women With Localized Breast Cancer
In this study, investigator propose to assess the prevalence of pelvic static disorders in women undergoing adjuvant hormone therapy for localized breast cancer and to assess the overall quality of life in these patients
- Trial name
- STATICBREAST (NCT04515888)
- Testing
- PFDI-20 / PFIQ-7 questionnaires
- Where
- France
- Volunteers
- 246 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Cancer of Rectum
Early Pelvic Floor Muscle Training Improves Pelvic Floor Muscle Strength in Patient After Low Anterior Resection
The aim of study is to investigate the difference in Maximum Squeeze Pressure in patients with and without pelvic floor muscle training in low anterior resection in peri-operative period
- Trial name
- NCT01146769
- Testing
- Pelvic floor exercise
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Kwong Wah Hospital
Abdominal Cancer, Pelvic Cancer
Ablative Stereotactic MR-Guided Adaptive Reirradiation
This research study will enroll people who have cancer in their abdomen or pelvis that was treated previously with radiation therapy.
- Trial name
- NCT06397573
- Testing
- Reirradiation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baptist Health South Florida
Diverticulum, Colon, Colorectal Neoplasms
Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing™ device in routine clinical practice at a single center.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- RETROPRESS (NCT01301417)
- Testing
- ColonRing™
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- novoGI
Urothelial Carcinoma
A Study of Ramucirumab (LY3009806) Plus Docetaxel in Participants With Urothelial Cancer
The main purpose of this study is to evaluate the safety and efficacy of the study drug ramucirumab in combination with docetaxel in participants with urothelial cancer who failed prior platinum-based therapy.
- Trial name
- RANGE (NCT02426125)
- Testing
- Ramucirumab, Docetaxel
- Where
- 141 sites in United States, Australia and 21 more
- Volunteers
- 530 people
- Sponsor
- Eli Lilly and Company
Distal Urethral Cancer, Proximal Urethral Cancer
Pazopanib in Treating Patients With Metastatic Urothelial Cancer
This phase II trial is studying the side effects and how well pazopanib works in treating patients with metastatic urothelial cancer.
- Conditions
- Distal Urethral Cancer, Proximal Urethral Cancer, Recurrent Bladder Cancer, Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter
- Trial name
- NCT00471536
- Testing
- pazopanib hydrochloride
- Where
- 9 sites in United States, China and 1 more
- Volunteers
- 19 people
- Sponsor
- National Cancer Institute (NCI)
Ovarian Neoplasms, Diagnoses Disease
Evaluation and Implementation of New Biomarkers and Algorithms for Diagnosis of Ovarian Cysts/Tumors in the Pelvis
This study evaluates the biomarkers CA125 and HE4 and the algorithms RMI and ROMA on a normal population in the western region of Sweden. The aim is to improve diagnosis of ovarian cancer.
- Conditions
- Ovarian Neoplasms, Diagnoses Disease, Biomarkers, Algorithms
- Trial name
- NCT03193671
- Testing
- Diagnosis
- Where
- Sweden
- Volunteers
- 684 people
- Sponsor
- Göteborg University
Endometrial Cancer
Pelvic Sentinel Node Detection Using Indocyanine Green Learning Curve
According to ESGO-ESTRO-ESMO guidelines, pelvic Sentinel lymph node detection is suitable for lymph node staging in endometrial carcinoma of the uteri.
- Trial name
- ENDO-GREEN (NCT04958278)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Rectum Cancer, Recurrent, Brachytherapy, Radioisotope
The Physical Dosimetry Study and Preliminary Clinical Results of 3D-printing Non Co-planar Template Assisted With CT-guidance for Iodine-125 Seed Brachytherapy in Pelvic Recurrent Rectum Carcinoma After Surgery and External Beam Radiotherapy
This study observes the efficacy and side effects of 3D-printing non co-planar template(3D-PNCT) assisted with CT-guidance for radioactive Iodine-125 seed(RIS) brachytherapy in pelvic recurrent rectum carcinoma retrospectively…
- Trial name
- NCT03890926
- Testing
- radioactive Iodine-125 seed implantation under the guidance of 3D template
- Volunteers
- 66 people
- Sponsor
- Peking University Third Hospital
Lower Abdominal Surgery, Pelvic Surgery
Objective to Evaluate the Safety and Effectiveness of LED Light Source System for Endoscopy in Ureteral Radiography
This clinical trial is a prospective, multi-center, single-blind, parallel, randomized controlled superiority clinical trial. The trial will be carried out in 5 centers, involving 120 subjects as estimated who will be divided…
- Trial name
- IRIS (NCT04561414)
- Testing
- LED light source system for endoscope, Ureteral stent (Cook Ireland Ltd.)
- Where
- 4 sites in China
- Sponsor
- Stryker Orthopaedics
Gynecologic Cancer, Surgical Procedure, Unspecified
Pelvic Exenteration and Laterally Extended Pelvic Resection
Growing evidence in literature is supporting the role of ultrasound scan (US) as accurate tool in diagnosis and staging of gynecologic cancers.
- Trial name
- Pre-PEX (NCT06278610)
- Testing
- PELVIC EXENTERATION
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometrial Cancer, Stage III Endometrial Cancer
A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer
The purpose of this study is to find out whether short-course radiation therapy (1 week instead of the usual 5 weeks) with chemotherapy (carboplatin and paclitaxel) is practical (feasible), meaning that most participants are able…
- Conditions
- Endometrial Cancer, Stage III Endometrial Cancer, Stage III Endometrial Carcinoma, Endometrial Carcinoma
- Trial name
- NCT05691010
- Testing
- Intensity-modulated radiation therapy, Carboplatin, Paclitaxel
- Where
- 7 sites in United States
- Volunteers
- 28 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Erectile Dysfunction Due to Arterial Insufficiency, Erectile Dysfunction
Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
The purpose of this study to perform a randomized, sham controlled analysis of the effectiveness of both fSWT and rWT in the relief of erectile dysfunction and chronic pelvic pain syndrome.
- Conditions
- Erectile Dysfunction Due to Arterial Insufficiency, Erectile Dysfunction, Erectile Dysfunction Due to Arterial Disease, Chronic Pelvic Pain Syndrome
- Trial name
- Shockwave (NCT05868668)
- Testing
- Focused shockwave, Radial wave
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- The Cleveland Clinic
Locally Advanced Rectal Cancer
SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer
The purpose of this research study is to find out how safe and effective is treating patients with locally advanced rectal cancer (LARC) with chemotherapy first and then follow with radiation therapy to a higher dose than what is…
- Trial name
- SMART TNT (NCT05412082)
- Testing
- Intensity-modulated radiation therapy, 5-fluorouracil, Leucovorin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Miami