Clinical trials: Cancer of the Thyroid
Pleomorphic Adenoma of the Parotid, Warthin Tumor
Identification of Nerves Using Fluorescein Sodium
The purpose of this study is to see if there is benefit in using an IV contrast (sodium fluorescein) to identify nerves during head and neck surgery.
- Conditions
- Pleomorphic Adenoma of the Parotid, Warthin Tumor, Head and Neck Disorder, Head and Neck
- Trial name
- NCT06054178
- Testing
- Fluorescein Sodium
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Bone Sarcoma, Dedifferentiated Chondrosarcoma
LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
This phase II trial studies how well autologous tumor infiltrating lymphocytes LN-145 (LN-145) or LN-145-S1 works in treating patients with ovarian cancer, triple negative breast cancer (TNBC), anaplastic thyroid cancer…
- Conditions
- Bone Sarcoma, Dedifferentiated Chondrosarcoma, Giant Cell Tumor of Bone, Malignancy in Giant Cell Tumor of Bone
- Trial name
- NCT03449108
- Testing
- Aldesleukin, Autologous Tumor Infiltrating Lymphocytes LN-145, Autologous Tumor Infiltrating Lymphocytes LN-145-S1
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Cancer
Study of External Beam Radiotherapy to Thyroid Carcinoma
The primary objective of this study is to estimate the 5 year locoregional control rate after External Beam Radiotherapy (EBRT) in the patient with locally advanced differentiated thyroid cancer.
- Trial name
- NCT01173289
- Testing
- External Beam Radiotherapy
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- National Cancer Center, Korea
KRAS G12D Mutation, Advanced Solid Cancer
A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation
This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer having a specific Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation.
- Trial name
- NCT07023731
- Testing
- ARV-806
- Where
- 14 sites in United States
- Volunteers
- 76 people
- Sponsor
- Arvinas Inc.
Papillary Thyroid Carcinoma, Thermal Ablation
A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid Carcinoma
A prospective cohort of papillary thyroid carcinoma(PTC), patients who received thermal ablation in our hospital since February 2023 was established as the study object.
- Trial name
- NCT05962892
- Testing
- No Intervention
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Friendship Hospital
Thyroid Cancer
Comparison of I-124 and I-131 Radiopharmacokinetics in DTC Patients With Thyroid Hormone Withdrawal
This research study is to compare the radiopharmacokinetics of I-124 to the radiopharmacokinetics of I-131 in patients who have well-differentiated thyroid cancer after thyroid hormone withdrawal.
- Trial name
- NCT02947399
- Testing
- Radioactive Iodine 124
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medstar Health Research Institute
Thyroid Nodule
Accuracy of FNAC in Diagnosis of Thyroid Nodules
Detection of degree of accuracy of FNAC in diagnosis of thyroid nodules
- Trial name
- NCT06782828
- Testing
- observe results of FNAC
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thyroid Neoplasm Follicular, Bone Metastases
Efficacy of Sr-89 for Differentiated Thyroid Cancer With Bone Metastases
Using sensitive markers (such as thyroglobulin, etc) to evaluate the efficacy of strontium-89 chloride (Sr-89) in differentiated thyroid cancer with bone metastases with an aim to breaking out of its palliation effect for bone…
- Trial name
- NCT05466812
- Testing
- Sr-89
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking Union Medical College Hospital
Thyroid Neoplasms, Thyroid Nodules
Is the Routine Pressure Dressing After Thyroidectomy Necessary?
Thyroidectomy is an operation that is commonly performed. After an operation a pressure dressing by Hypafix is usually used due to the belief that it will help to reduce complications such as post-operative bleeding or haematoma.
- Conditions
- Thyroid Neoplasms, Thyroid Nodules, Graves Disease, Goiter
- Trial name
- NCT00400465
- Testing
- Normal dressing, Pressure dressing
- Where
- Thailand
- Volunteers
- 116 people
- Sponsor
- Khon Kaen University
Adenocarcinoma (NOS), Anal Cancer
DESTINY-PANTUMOUR04
This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior systemic treatment for metastatic or advanced disease…
- Conditions
- Adenocarcinoma (NOS), Anal Cancer, Bladder Cancer, Cervical Cancer
- Trial name
- DP-04 (NCT07124000)
- Testing
- Trastuzumab deruxtecan
- Where
- 18 sites in United States
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Thyroid Cancer
The Effect of the Application of Head Mounted Magnifying Glasses on Postoperative PTH Changes in Thyroid Surgery
This study collected data on open thyroidectomy patients admitted to the Breast and Thyroid Surgery Department of Shandong Provincial Hospital from January 2020 to December 2023 by reviewing medical records.
- Trial name
- NCT06432257
- Testing
- head mounted magnifying glass assistance
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shandong Provincial Hospital
Endocrine Disruptor Chemicals, Thyroid Cancer
Role of Endocrine Disruptors in Thyroid Cancer
the relationship between human exposure to EDCS and TC is poorly investigated and still unclear. The aim of this study is to evaluate the possible role of old and new generation endocrine disruptors in thyroid cancer.
- Trial name
- THY-ED (NCT05747365)
- Testing
- Blood and urine diagnostic evaluation
- Where
- Italy
- Volunteers
- 222 people
- Sponsor
- Istituto Auxologico Italiano
Thyroid Cancer
Targeted Alpha Therapy Using Astatine (At-211) Against Differentiated Thyroid Cancer
Single intravenous administration of TAH-1005 is performed in patients with differentiated thyroid cancer (papillary cancer, follicular cancer) who cannot obtain therapeutic effect with standard treatment or who have difficulty…
- Trial name
- NCT05275946
- Testing
- Targeted alpha therapy
- Where
- Japan
- Volunteers
- 11 people
- Sponsor
- Osaka University
Thyroid Nodules, Thyroid Nodule
Comparing a New 3D Technology Used to Measure Thyroid Nodule Volume to Standard Ultrasound
After thyroid ablation procedure, the volume of the thyroid nodule (s) needs to be measured to see how well the procedure worked. Currently, these volumes are measured using traditional 2D ultrasound imaging.
- Trial name
- NCT07178080
- Testing
- PIUR tUS Infinity Ultrasound
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Sarasota Memorial Health Care System
Thyroid Carcinoma
Evaluation of the Clinical Utility of Circulating Biomarkers in Advanced Thyroid Carcinomas
The study is aimed at all adult patients diagnosed with advanced thyroid carcinomas and well-differentiated thyroid carcinomas (DTC) iodine-refractory, well-differentiated iodine-refractory thyroid (RAI-R DTC) metastatic…
- Trial name
- NCT06863805
- Testing
- 4 EDTA tubes of peripheral blood for Multigene analysis on ccf-DNA and ccf-RNA
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Adenocarcinoma of the Colon, Adenocarcinoma of the Gallbladder
Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer
Phase I trial to study the effectiveness of vaccine therapy with or without sargramostim in treating patients who have advanced or metastatic cancer. Vaccines may make the body build an immune response to kill tumor cells.
- Conditions
- Adenocarcinoma of the Colon, Adenocarcinoma of the Gallbladder, Adenocarcinoma of the Pancreas, Adenocarcinoma of the Rectum
- Trial name
- NCT00028496
- Testing
- recombinant fowlpox-CEA(6D)/TRICOM vaccine, sargramostim, recombinant fowlpox GM-CSF vaccine adjuvant
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Cancer Institute (NCI)
Malignant Neoplasms
A Study of DEG6498 in Participants With Solid Tumors
The goal of this first in human, Phase 1, multi-center, open-label, and 2-part study is to learn whether DEG6498 is safe and tolerable in participants with advanced solid tumors.
- Trial name
- NCT07244835
- Testing
- DEG6498
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Degron Therapeutics Co.
Thyroid Cancer
Quality of Life, Recombinant TSH (Thyrogen) and Thyroid Cancer
To evaluate quality of life in patients after 10 days pause of thyroid medication (Liothyronine) compared to treatment with recombinant TSH (Thyrogen) before radioiodine uptake and treatment in a double-blinded, randomised…
- Trial name
- NCT00604318
- Testing
- rhTSH
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Copenhagen University Hospital at Herlev
Thyroid Gland Carcinoma, Thyroid Cancer
Effect of Polyglycolic Acid Mesh (Neoveil) in Thyroid Cancer Surgery
This study is a randomized controlled study to investigate the effect of "Polyglycolic Acid Mesh Sheet (NeoveilTM)" on the thyroid cancer surgery.
- Conditions
- Thyroid Gland Carcinoma, Thyroid Cancer, Thoracic Duct Leak
- Trial name
- NCT03510143
- Testing
- Neoveil (Polyglycolic Acid Mesh)
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Seoul National University Hospital
Refractory Thyroid Gland Carcinoma, Refractory Thyroid Gland Papillary Carcinoma
Evaluation of 177Lu-DOTA-EB-FAPI in Patients With Metastatic Radioactive Iodine Refractory Thyroid Cancer
Increased fibroblast activation protein expression is positively correlated with the dedifferentiation and aggressiveness of thyroid cancer.
- Conditions
- Refractory Thyroid Gland Carcinoma, Refractory Thyroid Gland Papillary Carcinoma, Refractory Thyroid Gland Follicular Carcinoma, Refractory Thyroid Gland Hurthle Cell Carcinoma
- Trial name
- NCT05410821
- Testing
- 177Lu-DOTA-EB-FAPI 1 radionuclide therapy, 177Lu-DOTA-EB-FAPI 2 radionuclide therapy, 177Lu-DOTA-EB-FAPI 3 radionuclide therapy
- Where
- China
- Volunteers
- 12 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
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