Clinical trials: Cancer-Related Condition
Breast Cancer-Related Lymphedema, Lymphedema
Supermicrosurgical Lymphaticovenous Anastomosis for Prevention of Upper Limb Lymphedema
Breast cancer-related lymphedema (BCRL) is one of the most common chronic complications following breast cancer treatment. This study enrolls breast cancer patients who are required to undergo axillary lymph node dissection and…
- Conditions
- Breast Cancer-Related Lymphedema, Lymphedema, Breast Cancer Invasive
- Trial name
- SLVA-PULL (NCT07026292)
- Testing
- Immediate Distal Lymphaticovenous Anastomosis (ID-LVA)
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer
This phase II trial studies how well tacrolimus and mycophenolate mofetil works in preventing graft-versus-host disease in patients who have undergone total-body irradiation (TBI) with or without fludarabine phosphate followed by…
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT00089011
- Testing
- fludarabine phosphate, total-body irradiation, mycophenolate mofetil
- Where
- 5 sites in United States, Italy
- Volunteers
- 150 people
- Sponsor
- Fred Hutchinson Cancer Center
Obesity, Colorectal Cancer
Prevention of Obesity-related Cancers: Setting up of a Multi-Cancer Education and Prevention Program in Hong Kong
Obesity could increase the risk of many chronic diseases, including hypertension, cardiovascular diseases, high lipid level, diabetes, stroke, endometrial cancer and certain types of cancer which could benefit by secondary…
- Conditions
- Obesity, Colorectal Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT04034953
- Testing
- Faecal Immunochemical Test, Prostate-Specific Antigen Test, Mammogram
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cancer Pain
Optimizing Subcutaneous FEntanyl titRation: RApid Achievement of Adequate Exposure When Treating Cancer-Related paIn.
The primary objective is to evaluate the effect of loading boluses when dose incresaing treatment with SC fentanyl in patients with cancer.
- Trial name
- FERRARI (NCT06498037)
- Testing
- Fentanyl
- Where
- Netherlands
- Volunteers
- 45 people
- Sponsor
- Erasmus Medical Center
Depressive Symptoms, Cognitive Impairment
Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)
The goal of this clinical trial is to test a home-delivered intervention that combines Non-Invasive Brain Stimulation techniques (transcranial direct and alternating current stimulation -tDCS and tACS-) and Online Cognitive…
- Trial name
- ONCODEP (NCT06053775)
- Testing
- Transcranial Direct Current Stimulation, Transcranial Alternating Current Stimulation, Online Cognitive Training
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- University of Santiago de Compostela
Breast Cancer, Alcohol Drinking
Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits
This study is a single-arm feasibility trial evaluating a digital behavioral intervention designed to increase women's awareness of the relationship between alcohol use and breast cancer risk during routine breast cancer…
- Trial name
- NCT07799467
- Testing
- Sobriety Digital Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Miami
Early-stage Breast Cancer
Cardioprotective Effect of Acute Exercise in Breast Cancer Patients
Cardiotoxicity is one of the most significant adverse effects in breast cancer patients treated with anthracyclines (a type of chemotherapy), so we propose to determine whether acute training (i.e., 24h before each chemotherapy…
- Trial name
- CardioProtEx (NCT05467111)
- Testing
- Acute Exercise
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Technical University of Madrid
HPV-related Lower Genital Tract Neoplasias, HPV-related Anal Neoplasias
Screening Women With Prior HPV for Anal Neoplasia
The goal of this single arm trial is to prospectively evaluate screening methods for anal cancer precursors in HIV uninfected women with a history of lower genital tract neoplasias and cancers.
- Conditions
- HPV-related Lower Genital Tract Neoplasias, HPV-related Anal Neoplasias, Early Stage Lower Genital Tract Cancers
- Trial name
- SWAN (NCT05217940)
- Testing
- Diagnostic tests for anal cancer screening
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Breast Cancer Lymphedema
Warm Acupuncture for Breast Cancer Related Lymphedema
The purpose of this study is to clarify whether local-distal point association is more effective than local point association by warm acupuncture in the management of breast cancer related lymphedema.
- Trial name
- NCT03373474
- Testing
- local distribution points association, local-distal points association
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Tianjin University of Traditional Chinese Medicine
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute
Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)
Bone marrow transplants are one treatment option for people with leukemia or lymphoma. Family members or unrelated donors with a similar type of bone marrow usually donate their bone marrow to the transplant patients.
- Conditions
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute, Burkitt Lymphoma, Lymphoma, B-Cell
- Trial name
- NCT00849147
- Testing
- Haploidentical Bone Marrow Transplantation, GVHD prophylaxis
- Where
- 17 sites in United States
- Volunteers
- 55 people
- Sponsor
- Medical College of Wisconsin
Siblings, Childhood Cancer
SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer
This study aims to address barriers to psychosocial care for siblings of children with cancer by piloting a group-based telehealth program for adolescent siblings of youth with cancer.
- Conditions
- Siblings, Childhood Cancer, Pediatric Cancer, Posttraumatic Stress Disorder
- Trial name
- R03 CA259898 (NCT04889755)
- Testing
- SibACCESS
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Digestive System Cancer
Association Between Body Composition and Digestive System Cancer Survival
Investigators intend to utilize clinical data from the Department of Oncology at Jiangsu Provincial People's Hospital to analyze changes in body composition in digestive system tumor patients before and after receiving anti-tumor…
- Trial name
- NCT06054685
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Hepatitis B Virus, Hepatocellular Carcinoma
TACE and Adefovir Compared With Transarterial Chemoembolization (TACE) Alone for Hepatitis B Virus (HBV)-Related Unresectable Hepatocellular Carcinoma (HCC)
Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies in China, and approximately 90% of the patients with HCC are also infected with hepatitis B virus (HBV).
- Trial name
- TACE (NCT00960518)
- Testing
- adefovir, TACE
- Where
- 2 sites in China
- Volunteers
- 216 people
- Sponsor
- Tongji University
Lung Cancer
Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib
The proposed study seeks to address a critical gap in the management of lorlatinib-induced metabolic derangements, particularly rapid weight gain, which can adversely affect treatment adherence, dosing and ultimately patient…
- Trial name
- NSCLC (NCT07782359)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Metastatic or Locally Advanced NSCLC
Concomitant Radiotherapy, Tremelimumab & Durvalumab for Advanced NSCLC Patients Progressing on First-line Immunotherapy
This is an open-label, single-arm, phase 2a trial with a safety run-in cohort followed by a Simon two-step design expansion cohort, of two checkpoint blockage treatments and radiotherapy in the treatment of locally advanced or…
- Trial name
- CORAL-Lung (NCT05000710)
- Testing
- Durvalumab, Tremelimumab, Low dose irradiation
- Where
- Israel
- Volunteers
- 29 people
- Sponsor
- Sheba Medical Center
Cancer-related Fatigue
The Effects of a Food Product Containing Mushroom Extracts (AndoSanTM) in Subjects With Colorectal Cancer-related Fatigue
Effects of a food product containing mushroom extracts (AndoSanTM) in subjects with colorectal cancer-related fatigue. AndoSanTM is a specialized liquid food product that includes fermented extracts from the fungi Agaricus…
- Trial name
- NCT06599710
- Testing
- AndoSanTM
- Where
- 3 sites in Germany
- Sponsor
- Mycotech Pharma AS
Sarcoma, Kaposi, HIV Infections
A Study of AZT Plus Human Interferon Alpha in the Treatment of AIDS-Related Kaposi's Sarcoma
To evaluate the safety and toxicity of combination therapy for AIDS-associated Kaposi's sarcoma with zidovudine (AZT) and two kinds of interferon alpha.
- Trial name
- NCT00001113
- Testing
- Interferon alfa-2a, Zidovudine, Interferon alfa-n1
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Breast Cancer, Non Hodgkin Lymphoma
PROACT: Can we Prevent Chemotherapy-related Heart Damage in Patients With Breast Cancer and Lymphoma?
PROACT will establish the effectiveness of the angiotensin-converting enzyme inhibitor (ACEI) enalapril maleate (enalapril) in preventing cardiotoxicity in patients with breast cancer and non-Hodgkin lymphoma undergoing adjuvant…
- Trial name
- PROACT (NCT03265574)
- Testing
- Enalapril
- Where
- United Kingdom
- Volunteers
- 111 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Breast Neoplasms, Breast Reconstruction
DIEP-MDS for Risk Stratification of Flap Vascular Compromise and Failure in Breast Reconstruction
This multicenter retrospective observational study will develop and validate a CTA-based quantitative risk score-the DIEP Morphological Deviation Score (DIEP-MDS)-to estimate the risk of flap-related vascular compromise and flap…
- Conditions
- Breast Neoplasms, Breast Reconstruction, Postoperative Complications
- Trial name
- DIEP-MDS (NCT07761390)
- Where
- 20 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Zhuliling
Alzheimer Disease, Dementia, Mild
Event-Related Potential (ERP) Components in Clinical Diagnosis
In this study, the investigators will use a novel electroencephalogram (EEG) system that participants will wear during a single in-person research session to investigate whether ERPs are now ready for validation as a tool…
- Conditions
- Alzheimer Disease, Dementia, Mild, Mild Cognitive Impairment
- Trial name
- NCT05673759
- Testing
- Electroencephalogram (EEG) system, Standard Neuropsychological Testing, Additional neuropsychological tests
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Boston University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.