Clinical trials: Cancer-Related Condition
Esophageal Cancer
Complete Clinical Responders to Definite Chemoradiation in Esophageal Cancer : a Survival Analysis
The aim of this study is to identify prognostic factors for outcome in patients being complete clinical responders with chemoradiation or radiation for esophageal cancer
- Trial name
- CRCRT-EC (NCT01525953)
- Testing
- Chemotherapy, Radiotherapy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Oscar Lambret
Cancer, Critically Ill
Protein Intake Associated With Physical Activity Related to Specific Outcomes
This is a Randomized Controlled Trial . The purpose of this study is to assess the hypothesis that whether a high protein diet combined with a physical activity protocol in surgical cancer patients admitted to the ICU in the post…
- Conditions
- Cancer, Critically Ill, Surgery
- Trial name
- STRENGTH (NCT03438201)
- Testing
- Intervention, Control
- Where
- Brazil
- Volunteers
- 126 people
- Sponsor
- University of Sao Paulo
Breast Cancer
A Prospective Observational Study About Adjuvant or Neoadjuvant Chemotherapy Related Adverse Effects in Postmenopausal Breast Cancer Patients
Breast cancer is one of the most common malignant tumor in women. About 69.75% of breast cancer women patients in China are over 45 years old. It is a multicenter prospective observational study.
- Trial name
- NCT03543072
- Testing
- Bisphosphonates
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-sen University
Acute Leukemia, Acute Myeloid Leukemia
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders
This is a Phase II study of allogeneic hematopoietic stem cell transplant (HCT) using a myeloablative preparative regimen (of either total body irradiation (TBI); or, fludarabine/busulfan for patients unable to receive further…
- Conditions
- Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Lymphoma
- Trial name
- NCT03314974
- Testing
- HSCT with TBI Regimen, HSCT with Non-TBI Regimen
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Breast Cancer, Cardiotoxicity
Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion Study
This is a companion study to the "Pragmatic Randomized Trial of Proton vs Photon Therapy for Patients with non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RadComp)…
- Trial name
- NCT04361240
- Testing
- Proton vs Photon Radiation
- Where
- 6 sites in United States
- Volunteers
- 172 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant
This phase II clinical trial tests how well the cytomegalovirus-modified vaccinica Ankara (CMV-MVA) Triplex vaccine given to human leukocyte antigens (HLA) matched related stem cell donors works to prevent cytomegalovirus (CMV)…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, BCR-ABL1 Positive
- Trial name
- NCT06059391
- Testing
- Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Granulocyte Colony-Stimulating Factor
- Where
- 3 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Acute Lymphoblastic Leukemia, Pediatric
Parental Perception of Their Child's Emotional Quality of Life in Paediatric Oncology Before and After "Magic Massages"
Rationale: In France, 1,850 cases of cancer are diagnosed in children every year (28% of leukaemia). Despite a cure rate of 83% (all cancers combined), treatment remains a major burden.
- Trial name
- MASSAYA (NCT06107478)
- Testing
- Self-report questionnaires (only for parents), Interview (only for parents), Clinical data collection (only concerning Children)
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Neoplasms, Colorectal, General Practitioner
Delay to Diagnosis in Digestive Cancerology by the General Practitioner Related to Covid-19 Pandemic Confinement
Objective: the pre-hospital management of cancers is little known in General Medicine. The first lockdown related to the COVID-19 pandemic led to the closure of health facilities.
- Conditions
- Neoplasms, Colorectal, General Practitioner, Pandemic, COVID-19, Neoplasm, Liver
- Trial name
- NCT06118125
- Where
- France
- Volunteers
- 376 people
- Sponsor
- University of Bordeaux
Mycobacterium Avium-Intracellulare Infection, HIV Infections
The Effects of Treatment for Mycobacterium Avium Complex (MAC) on the Cells of HIV-Infected Patients
To determine if treatment of MAC infection in HIV-1 infected persons is associated with the decreases in plasma levels of TNF-alpha. Infection with MAC is a poor prognostic indicator in persons with AIDS.
- Trial name
- NCT00000860
- Where
- 11 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hospice, Psilocybin
Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care
The overall objective of this study is to develop and pilot test a novel regimen of psilocybin-assisted psychotherapy for demoralization in patients receiving hospice care.
- Conditions
- Hospice, Psilocybin, Demoralization, Terminal Illness
- Trial name
- PATH (NCT04950608)
- Testing
- Psilocybin, Psychotherapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yvan Beaussant, MD, MSci
Cancer, Ovarian
Efficacy of Topotecan and Lapatinib in Early Recurrent Ovarian or Peritoneal Cancer
The objective of the trial was to evaluate the efficacy of the association of topotecan and lapatinib in patients who failed first line platinum-based chemotherapy within 12 months.
- Conditions
- Cancer, Ovarian, Relapse, Chemotherapy
- Trial name
- TOPO-LAPA (NCT00888810)
- Testing
- TOPOTECAN, LAPATINIB
- Where
- 21 sites in France
- Volunteers
- 39 people
- Sponsor
- Centre Francois Baclesse
HIV-Associated Malignant Neoplasm, HIV Infections
Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC
This study is being done to understand how many people with HIV (PWH) present for cancer care across the AIDS Malignancy Consortium in the United States and if there are reasons that some PWH choose to participate, or not in…
- Conditions
- HIV-Associated Malignant Neoplasm, HIV Infections, Cancer, AIDS Related Lymphoma
- Trial name
- NCT05510908
- Testing
- Non-Interventional, Non-Interventional Follow-up
- Where
- 16 sites in United States, Puerto Rico
- Volunteers
- 460 people
- Sponsor
- AIDS Malignancy Consortium
Bladder Cancer, Cervical Cancer
Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking
RATIONALE: Stop-smoking plans, including counseling and nicotine replacement therapy, may help smokers quit smoking. It is not yet known whether counseling and the nicotine lozenge is more effective than counseling and the…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00365508
- Testing
- nicotine lozenge, nicotine patch
- Where
- 10 sites in United States
- Volunteers
- 642 people
- Sponsor
- Fox Chase Cancer Center
Cancer Therapy-Related Cardiac Dysfunction
Cardiac Rehabilitation Program on the Prevention of Cardiotoxicity in Breast Cancer Patients Undergoing Treatment With Anthracyclines and/or Trastuzumab
This study aims to evaluate the effectiveness of a cardiac rehabilitation protocol, incorporating aerobic and resistance exercise, in reducing the incidence of cardiotoxicity in breast cancer patients receiving treatment with…
- Trial name
- CARPTOX-BC (NCT06881940)
- Testing
- Rehabilitation Program, No Rehabilitation Program
- Where
- 2 sites in Mexico
- Volunteers
- 284 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
HIV-related Lymphoma, HIV Infections
High Dose Therapy and Peripheral Blood Stem Cell Transplantation in HIV Related Non Hodgkin Lymphoma (NHL) at High Risk
The purpose of the study is to evaluate the efficacy of an intensified first-line treatment, with conventional chemotherapy (CHOP) plus monoclonal antibody anti CD20, followed by high dose chemotherapy and PBSC transplantation in…
- Trial name
- HDT-HIV (NCT01045889)
- Testing
- Rituximab and CHOP regimen + PBSCT
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Stage IIIC Ovarian Cancer
Surgical Complications Related to Primary or Interval Debulking in Ovarian Neoplasm
Patients with advanced ovarian cancer (FIGO stage III C) and highly disseminated tumor will be randomized into two arms: primary debulking surgery followed by adjuvant chemotherapy vs.
- Trial name
- SCORPION (NCT01461850)
- Testing
- Neoadjuvant chemotherapy + Interval Debulking Surgery, Primary Debulking Surgery + Adjuvant Chemotherapy
- Where
- Italy
- Volunteers
- 171 people
- Sponsor
- Catholic University of the Sacred Heart
Metastatic Breast Cancer
Phase 2 Study of Pembrolizumab+Carboplatin in Breast Related Cancer Antigens-related Metastatic Breast Cancer (PEMBRACA)
This is a prospective two-stage single arm phase II study to be conducted in conformance with Good Clinical Practices. This study will enrol 53 patients, based on a two steps Simon's design.
- Trial name
- NCT03732391
- Testing
- Pembrolizumab 25 MG(milligram)/ML
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- CORTESI LAURA
Breast Cancer, Chemotherapy-Related Cognitive Impairment
Individualized Piano Instruction (IPI) for Improving Cognition in Breast Cancer Survivors.
The purpose of this study is to test the study method and procedure for individualized piano instruction (IPI) and its impact on chemotherapy related cognitive impairment (CRCI) symptoms.
- Trial name
- NCT05909813
- Testing
- Individualized Piano Keyboard Instruction
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Miami
Opioid-induced Constipation
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
This study will evaluate the safety and efficacy of Tegaserod in opioid-induced constipation in patients with non-cancer pain. Patients who enter this study PRIOR to the core study (CHTF919N2201) interim analysis receive the…
- Trial name
- NCT00414024
- Testing
- Tegaserod
- Where
- 6 sites in United States, China and 4 more
- Volunteers
- 11 people
- Sponsor
- Novartis
Breast Cancer Related Lymphedema, Deep Learning
Study on Classification Method of Indocyanine Green Lymphography Based on Deep Learning
Breast cancer related lymphedema (BCRL) is the most common complication after breast cancer surgery, which brings a heavy psychological and spiritual burden to patients.
- Trial name
- BCRL；ICG (NCT04824378)
- Testing
- No Intervention.
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
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