Clinical trials: Cancer-Related Condition
Opioid-Induced Constipation, Pain Cancer
Real World Study of Oxycodone/Naloxone Sustained-Release Tablets (Mimeixin) for Patients With Severe Cancer Pain
This study is a prospective, single-arm, multicenter, real-world study to evaluate effect of bowel function, analgesic effect, quality of life, and safety of Mimeixin® in Chinese patients with severe cancer pain.
- Trial name
- NCT06897917
- Testing
- Oxycodone Hydrochloride and Naloxone Hydrochloride Sustained-release Tablets
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Henan Cancer Hospital
Hypothermia; Anesthesia, Hyperthermia, Anesthesia Related
Inadvertent Hypothermia or Hyperthermia in Pediatric Radiotherapy Practices Under Anesthesia
In prospective, observational cohort study, changes in body temperature will be investigated before the procedure and during recovery in Radiotherapy patients aged 0-18 years who need sedation due to childhood malignancies.
- Conditions
- Hypothermia; Anesthesia, Hyperthermia, Anesthesia Related, Radiotherapy Side Effect, Childhood Cancer
- Trial name
- NCT05478850
- Testing
- radiotherapy under anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Ankara City Hospital Bilkent
Neurofibromatosis 2
Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients
The purpose of the study is to determine if RAD001 treatment will shrink or slow the growth of the vestibular schwannoma(s) in Neurofibromatosis 2 (NF2) patients.
- Trial name
- AFINF2 (NCT01490476)
- Testing
- RAD001
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Severe Asthma
Defining the Severe Paediatric Asthma Endotype
The primary objective of this project is to extensively characterize the endotypes of pre-schoolers (0 to 6 years) and school-age children (6 to 12 years) with SA using an integrated approach, combining a description of their…
- Trial name
- SevAsthma (NCT04680117)
- Testing
- Blood collection, Saliva sample, Nasal
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metastatic Breast Cancer
Liposomal Doxorubicin and Docetaxel in Metastatic Breast Cancer
Evaluation of safety and efficacy of a treatment associating Pegylated Liposomal Doxorubicin + Docetaxel in patients with metastatic breast cancer
- Trial name
- NCT00524810
- Testing
- Pegylated liposomal doxorubicin, Docetaxel
- Where
- France
- Volunteers
- 67 people
- Sponsor
- ARCAGY/ GINECO GROUP
Gastric Cancer, Diabetes Mellitus, Type 2
Surgical TreAtment for Obesity Related Disease and Onco-Metabolic Surgery
This is a prospective, multi-center, randomized controlled trial to compare Billroth II reconstruction versus conventional Roux-en-Y reconstruction versus long limb Roux-en-Y reconstruction for glycemic control in patients with…
- Trial name
- STARDOM (NCT04284943)
- Testing
- Long limb Roux-en-Y reconstruction after subtotal gastrectomy, Conventional Roux-en-Y reconstruction after subtotal gastrectomy, Billroth II reconstruction after subtotal gastrectomy
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Korea University Anam Hospital
Neoplasms, Blood Cancer
Take the Reins: The Effects of Nutrient Timing on Cancer-related Fatigue
Cancer-related fatigue affects at least 30-90% of patients with cancer, depending on the type of cancer and their treatment(s) (e.g., chemotherapy, radiation).
- Conditions
- Neoplasms, Blood Cancer, Fatigue, Diet Habit
- Trial name
- NCT06482515
- Testing
- Time-restricted eating, Nutrition counseling
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Maryland, Baltimore
Breast Cancer, Colorectal Cancer
Feasibility of Quality of Life Assessment in Routine Clinical Oncology Practice at the University Hospital of Besancon
Symptoms related to the disease and/or treatment are common in cancer patients and can affect patient health-related quality of life (HRQol). Unfortunately these symptoms can be underestimated and underreported by the physician.
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer
- Trial name
- QOLIBRY (NCT02844608)
- Testing
- Quality of Life Questionnaires
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Colon Cancer, MTHFR Gene Mutation
C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine Effectiveness in Metastatic Colon Cancer
Fluoropyrimidines are the backbone of chemotherapy regimes used to treat metastatic colorectal cancer (CRC). These drugs act in different pathways of folate metabolism altering DNA synthesis mainly by inhibition of the tymidylate…
- Conditions
- Colon Cancer, MTHFR Gene Mutation, Chemotherapeutic Toxicity, Chemotherapy Effect
- Trial name
- NCT03852290
- Where
- Costa Rica
- Volunteers
- 65 people
- Sponsor
- Universidad de Costa Rica
Cancer, Metastasis Lung
Relationship Between Circulating Tumor Cell Cultures' Treatment Response and Clinical Outcomes
The purpose of this prospective, non-randomized, single-center pilot exploratory study is to investigate whether established circulating tumor cell (CTC) cultures have a similar response to targeted therapy treatment as the in…
- Conditions
- Cancer, Metastasis Lung, Metastasis to Liver, Circulating Tumor Cell
- Trial name
- NCT04280640
- Testing
- Blood Draw
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Polycystic Ovary Syndrome
Intestinal Microbiota Survey of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is kind of disease with unclear etiology. Recent studies on intestinal microbiota have raised the possibility that dysbiosis of intestinal microbiota maybe a novel theory for the development of…
- Trial name
- NCT02937090
- Testing
- Blood Draw, Stool collection
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Cervical Carcinoma, Human Papillomavirus-Related Carcinoma
Prevention and Early Detection of Cervical Cancer Through Self-Administered Screening
This study examines prevention and early detection of cervical cancer through self-administration screening of patients in Western Uganda.
- Trial name
- NCT04927650
- Testing
- HPV testing, Questionnaire Administration
- Where
- Uganda
- Volunteers
- 2,556 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer, Cancer-Related Syndrome
Effects of a Multimodal Physical Exercise and Functional Rehabilitation Program on Fatigue, Pain, Functional Capacity and Quality of Life in Cancer Patients With Tumor Asthenia.
Tumor asthenia is the most common symptom associated with cancer and its treatment. Although the estimated prevalence varies between 60-90%, and it is considered the longest-lasting symptom in cancer patients, having the greatest…
- Conditions
- Cancer, Cancer-Related Syndrome, Fatigue
- Trial name
- NCT04761289
- Testing
- Multimodal Exercise and Functional Rehabilitation Program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Metastatic Breast Cancer, Cancer-Related Fatigue
Multimodal Exercise and Education Program in Metastatic Breast CancerMostrar más líneas
This longitudinal pre-post study evaluates the effects of a 12-week community-based multimodal intervention combining supervised physical exercise and health education in women with metastatic breast cancer receiving active…
- Conditions
- Metastatic Breast Cancer, Cancer-Related Fatigue, Quality of Life
- Trial name
- MBC_MME (NCT07693985)
- Testing
- Multimodal Oncology-Based Intervention for Metastatic Breast Cancer
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- University of Valencia
Chronic Myeloid Leukemia
Activity and Safety of Front-line Venetoclax and Rituximab in Young and Fit Patients With Chronic Lymphocytic Leukemia
Fludarabine, cyclophosphamide, and rituximab (FCR) is the gold treatment for fit and young patients with Chronic Lymphoid Leukemia (CLL).
- Trial name
- VeRitAs (NCT03455517)
- Testing
- Venetoclax, Rituximab
- Where
- 31 sites in Italy
- Volunteers
- 77 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Breast Cancer Related Lymphedema
Effect of BOSU Exercises Added to Complete Decongestive Treatment on Balance in Breast Cancer-associated Lymphedema.
The aim of the study is to investigate the effect of balance exercises performed with the BOSU ball added to complete decongestive treatment on static and dynamic balance in patients with breast cancer-related lymphedema.
- Trial name
- NCT06182046
- Testing
- Complete decongestive treatment program, Balance exercises
- Volunteers
- 40 people
- Sponsor
- Oya Topuz
Basal Cell Carcinoma of Skin, Cutaneous Squamous Cell Carcinoma (CSCC)
Impact of Preoperative High-Frequency Ultrasound Cutaneous Lesion Extent Assessment on Excision Margin Positivity in Head and Neck Skin Cancer, and the Relationship Between Preoperative Assessment Methods, Inadequate Excision Margins, and Tumor Recurrence
Non-melanoma skin cancers (NMSC), particularly basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), are the most common malignancies in Caucasians, with the majority of tumors located in the head and neck due…
- Conditions
- Basal Cell Carcinoma of Skin, Cutaneous Squamous Cell Carcinoma (CSCC), Cutaneous Squamous Cell Carcinoma in Situ (CSCCis), Cutaneous Squamous Cell Carcinoma of the Head and Neck
- Trial name
- HFUS-CLEAR (NCT07361666)
- Testing
- High-Frequency Ultrasound, Dermoscopy
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji
Drug/Agent Toxicity by Tissue/Organ, Lung Cancer
Amifostine to Prevent Side Effects in Patients Who Are Receiving Chemotherapy and Radiation Therapy for Limited-Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Drugs such as amifostine may protect normal cells from the side effects of chemotherapy and radiation…
- Conditions
- Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Radiation Toxicity
- Trial name
- NCT00003583
- Testing
- amifostine trihydrate, cisplatin, etoposide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Breast Cancer
Radiation Therapy in Treating Women With Invasive Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
- Trial name
- NCT00301041
- Testing
- laboratory biomarker analysis, adjuvant therapy, radiation therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Acute Exercise Cardioprotection From Doxorubicin
In rodents, a single bout of exercise prior to injection of a chemotherapy agent used to treat breast cancer prevents or attenuates a number of markers of cardiac injury.
- Trial name
- NCT02006979
- Testing
- exercise
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of British Columbia
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