Clinical trials: Cancer-associated Cachexia
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Anorexia
Olanzapine Anorexia Cachexia
164 patients will be recruited..Adult patients diagnosed with incurable solid tumors and CCAA who presented to Kasr Al-Ainy Center of Clinical Oncology and Nuclear Medicine (NEMROCK) - Kasr Al-Ainy School of Medicine - Cairo…
- Trial name
- NCT05243251
- Testing
- Olanzapine 5 MG
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Cairo University
Cachexia, Lymphoma
Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer
RATIONALE: Nutritional supplements may help prevent loss of appetite, weight loss, and fatigue in patients with advanced cancer.
- Conditions
- Cachexia, Lymphoma, Lymphoproliferative Disorder, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00053053
- Testing
- Juven, Non-Juven Supplement
- Where
- 250 sites in United States, Canada
- Volunteers
- 472 people
- Sponsor
- Radiation Therapy Oncology Group
Breast Cancer, Cachexia
Effect of Dietary Counseling and Nutritional Monitoring in Reducing Cancer-related Cachexia Among Female Oncology Patients
In this parallel, two-arm randomized controlled trial (RCT), 140 female patients with advanced-stage breast cancer and clinical features of cachexia will be randomized using block-stratified allocation into an intervention group…
- Trial name
- NCT07112482
- Testing
- Standard Oncological Care + Tailored Dietary Counseling + Nutritional Monitoring
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Pakistan Society of Pediatric Oncology
Extensive-stage Small Cell Lung Cancer (ES-SCLC), Cancer - Associated Anorexia - Cachexia Syndrome
Nanocrystalline Megestrol Acetate for the Treatment of Anorexia-Cachexia Syndrome in Extensive-Stage Small Cell Lung Cancer: A Prospective, Open-Label, Single-Arm Phase II Clinical Study
Patients with extensive-stage small cell lung cancer are a high-risk group for cancer cachexia and anorexia. Meanwhile, the adverse reactions of chemotherapy and immunotherapy potentially exacerbate the occurrence and development…
- Trial name
- NCT06909383
- Testing
- Nanocrystalline megestrol acetate
- Volunteers
- 41 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Adjustment Disorder, Adjustment Disorder With Anxious Mood
Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder
This study is assessing the efficacy and safety of NPX-5 in psilocybin-assisted psychotherapy for the treatment of adjustment disorder due to cancer diagnosis.
- Conditions
- Adjustment Disorder, Adjustment Disorder With Anxious Mood, Cancer, Cancer Cachexia
- Trial name
- NCT07072728
- Testing
- Psilocybin therapy
- Where
- 3 sites in Australia
- Volunteers
- 87 people
- Sponsor
- Psyence Australia Pty Ltd
Cachexia; Cancer; Sarcopenia
Study on the Pathogenesis and Reversal Strategies of Cancer Cachexia Based on Multi-Omics
Cancer cachexia is a complex systemic metabolic syndrome with high incidence and mortality rates, significantly impacting the prognosis and survival of cancer patients.Current clinical comprehensive intervention approaches can…
- Trial name
- PRCC-MO (NCT07519837)
- Testing
- Validation of intervention efficacy through enhanced intervention in nutritionally high-risk patients, Standard nutritional intervention was administered as a positive control to validate experimental efficacy.
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China Medical University, China
Cachexia, Pancreatic Cancer
Pilot Project for Cardiopulmonary and Functional Evaluation in Patients With Pancreatic Cancer Associated Cachexia
Cachexia is a systemic catabolic syndrome with apparent effect on skeletal muscles, tolerance to chemotherapy, early toxicity and quality of life; however, its effect on cardiopulmonary function is not well understood.
- Trial name
- NCT02580422
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Cancer-associated Cachexia
Visugromab in Cachexia International Trial
A study of how well and safely a new drug called visugromab works in people with certain kinds of cancer (including lung and bowel cancer) and unintended weight loss known as cachexia.
- Trial name
- VINCIT (NCT07112196)
- Testing
- Visugromab (CTL-002)
- Where
- 74 sites in United States, Bulgaria and 10 more
- Volunteers
- 518 people
- Sponsor
- CatalYm GmbH
Anorexia, Cachexia
Creatine in Treating Patients With Cancer-Associated Weight Loss
RATIONALE: It is not yet known whether the supplement creatine is effective in increasing weight and improving appetite and quality of life in patients who have cancer.
- Conditions
- Anorexia, Cachexia, Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
- Trial name
- NCT00081250
- Testing
- creatine monohydrate
- Where
- 220 sites in United States
- Volunteers
- 300 people
- Sponsor
- Alliance for Clinical Trials in Oncology