Clinical trials: Candidemia, active
Candidemia, Candidiasis, Invasive
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Fosmanogepix) for the potential treatment of candidemia and/or invasive candidiasis, a life-threatening fungal infection…
- Trial name
- NCT05421858
- Testing
- Fosmanogepix, Caspofungin, Fluconazole
- Where
- 146 sites in United States, Argentina and 18 more
- Volunteers
- 450 people
- Sponsor
- Basilea Pharmaceutica
Candidemia, Invasive Candidiasis
Shortening Treatment Duration in Uncomplicated Candidemia: the CanTEN Trial
CanTEN is a multicenter, randomized, double-blind, placebo-controlled, adaptive, non-inferiority phase 4 trial investigating a shortened treatment duration in patients with uncomplicated candidemia.
- Trial name
- CanTEN (NCT07788586)
- Testing
- Caspofungin only within the study, Caspofungin for 3 days within the study
- Where
- 24 sites in Germany
- Volunteers
- 420 people
- Sponsor
- Oliver Cornely, MD
Candidemia
A Study Comparing Short-course Antifungal Therapy (SCAT) 7 Day vs Standard 14 Day Antifungal Therapy for Uncomplicated Candidemia
The goal of this clinical trial is to assess whether a seven-day course of standard of care (echinocandin) antifungal therapy is non-inferior to a 14-day course of echinocandin antifungal therapy in patients with uncomplicated…
- Trial name
- SCAT (NCT06907992)
- Testing
- Antifungal treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Augusta University
CANDIDEMIA
A Randomized Study of a Short Duration Therapy for Candidemia
Scientific justification Candidemia is a major public health problem. In France, the 30-day mortality of candidemia varies from 30% to 50% depending on the need for intensive care and it has not decreased in 30 years.
- Trial name
- CANDISHORT (NCT06859671)
- Testing
- Standard of Care (SOC), Shortened duration of antifungal therapy
- Volunteers
- 362 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris