Clinical trials: Canker Sore
Aphthous Stomatitis
Efficacy and Safety of BNP105 in the Treatment of Recurrent Aphthous Stomatitis
The purpose of this study is to evaluate the efficacy and safety of BNP105 in the treatment of recurrent aphthous stomatitis.
- Trial name
- NCT05772338
- Testing
- BNP105 (25 + 25 + 15)
- Where
- 2 sites in Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- EMS
Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis
Effectiveness of Recurrent Aphthous Stomatitis Mouthwash System for the Treatment of Oral Ulcers
The purpose of the present research is to evaluate the efficacy of a gel formulation for a total treatment of 14 days for the treatment of traumatic or aphthous oral ulcers.
- Trial name
- RASMA (NCT07121361)
- Testing
- Mouthwash Product, Control
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Aphthous Stomatitis
Effectiveness and Safety of Lactobacillus Rhamnosus Lcr35® in the Treatment of Recurrent Aphthous Stomatitis
Recurrent aphthous stomatitis (RAS) is a frequent condition characterized by recurrent and painful oral ulcers with unknown pathophysiology. Recent studies suggest that a dysregulation of the oral microbiota may be implicated.
- Trial name
- Aphtose (NCT02789605)
- Testing
- Bacilor
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Recurrent Aphthous Stomatitis
Oral Vitamin B12 as Potential Treatment of Recurrent Aphthous Stomatitis
Background: Recurrent aphthous stomatitis is a common phenomenon in Primary Medicine.Frequency of the phenomenon can be as high as 25% of the general population and the recurrence of the problem can be up to 50%.Different…
- Trial name
- NCT00288769
- Where
- Israel
- Sponsor
- Soroka University Medical Center
HIV Infections, Stomatitis, Aphthous
Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection
PRIMARY: To evaluate the effectiveness and safety of thalidomide for treatment of oral and esophageal aphthous ulcers (those unrelated to a known infection or malignancy) in patients with advanced HIV disease.
- Trial name
- NCT00000790
- Testing
- Thalidomide
- Where
- 40 sites in United States, Puerto Rico
- Volunteers
- 164 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Aphthous Ulcer
Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients
The purpose of this study is to compare the efficacy of laser photobiomodulation and "Magic Mouthwash" for treatment of pain in pediatric patients with aphthous ulcers , to assess how photobiomodulation influences the rate of…
- Trial name
- NCT06819033
- Testing
- PBM Therapy, Maalox plus Benadryl
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Aphthous Stomatitis
Prevention of Recurrent Aphthous Stomatitis Using Vitamins
The purpose of this research study is to find out if taking a multivitamin daily can affect the number of canker sores that people get and how long they last.
- Trial name
- NCT00527306
- Testing
- multivitamin
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- UConn Health
Mouth Sores
Post-marketing Study for the Evaluation of Profilm Mouth Sores
The study aims to assess the effect of Profilm Mouth Sores treatment for relieving symptoms caused by mouth sores. It will involve 35 participants and last around 14 days or until the sores heal, with three daily applications.
- Trial name
- NCT06741280
- Testing
- Profilm Mouth Sores
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- i+Med S.Coop.
Aphthous Stomatitis
Tokushima Night Guard for Recurrent Aphthous Stomatitis
The investigators will investigate whether the night guard can suppress the development of recurrent aphthous stomatitis (RAS). The investigators will record the patients' oral condition for 60 days before and after intervention…
- Trial name
- NCT02890524
- Testing
- night guard
- Where
- 2 sites in Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Tokushima
Recurrent Aphthous Stomatitis, Oral Ulcers
Efficacy of 5% Chitosan Nanoparticle Paste in the Treatment of Recurrent Aphthous Stomatitis
The purpose of this study is to evaluate the therapeutic clinical efficacy of a synthesized 5 wt.% chitosan nanoparticle paste compared to a standard topical corticosteroid (triamcinolone acetonide 0.1% oral paste) in patients…
- Trial name
- NCT07702474
- Testing
- Triamcinolone Acetonide 0.1% Oral Paste, 5 wt.% Chitosan Nanoparticle Paste
- Volunteers
- 30 people
- Sponsor
- Kerman University of Medical Sciences
Recurrent Aphthous Stomatitis
Influence of Different Doses of the Vitamin B12 on Recurrent Aphthous Stomatitis
Background: The frequency of recurrent aphthous stomatitis (RAS), the most common oral mucosa lesions seen in primary care, is up to 25% in the general population.
- Trial name
- NCT01127724
- Testing
- vitamin B12 treatment
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Meir Medical Center
Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis Syndrome
Efficacy and Safety of Thalidomide for Pediatric PFAPA Syndrome
The goal of this clinical trial is to evaluate the efficacy and safety of thalidomide in the treatment of children with Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) syndrome.
- Trial name
- NCT07476625
- Testing
- Thalidomide (50mg), Colchicine
- Volunteers
- 106 people
- Sponsor
- Wenjie Zheng
Aphthous Stomatitis (Major) (Minor), Treatment Compliance
Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers
Recurrent aphthous stomatitis (RAS) is considered the most common oral mucosal lesion, present first in childhood or adolescence.
- Trial name
- NCT06421038
- Testing
- Thyme honey, Kenalog
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- British University In Egypt
Recurrent Aphthous Stomatitis
α-Mangostin Hydrogel Film With Chitosan Alginate Base for Recurrent Aphthous Stomatitis (RAS)
Recurrent Aphthous Stomatitis (RAS) is experienced by almost everyone and appears suddenly. Even though the risk of death due to the condition is small, its presence can make a person feel uncomfortable eating, drinking, and…
- Trial name
- AM-RAS (NCT06039774)
- Testing
- α-Mangostin Hydrogel Film With Chitosan Alginate Base
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Universitas Padjadjaran
Aphthus Ulcer
Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers
Interventions of both groups: Oxygenated gel Group: 15 patients who used oxygenated gel (Blue®m, Wijhe, Netherlands) were trained by the co-investigator (A.H) through real demonstration for topical application of the gel on…
- Trial name
- NCT06910579
- Testing
- topical application of oxygenated gel, topical application of Triamcinolone acetonide gel
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- British University In Egypt
Recurrent Aphthous Stomatitis
The Efficacy of Erythropoietin Oral Gel Versus Erythropoietin Mouthwash in the Management of Recurrent Aphthous Stomatitis
Erythropoietin (EPO) exerts anti-inflammatory effects by inhibiting NF- kappa B-dependent formation of pro-inflammatory cytokines, thus it reduces local and circulating levels of these disease (recurrent aphthous stomatitis RAS)…
- Trial name
- NCT06923605
- Testing
- Epoetin 4000
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Future University in Egypt
Stomatitis, Aphthous
Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation
The aim this study was to investigate the efficacy of Er,Cr:YSGG laser irradiation in reducing pain and on healing rate of recurrent aphthous stomatitis 40 patients with RAS were included to the study.
- Trial name
- NCT02925182
- Testing
- Er,Cr:YSGG Laser
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Aphtous Ulcers
Efficacy of the Combination Bismuth + Neomycin + Procaine in the Treatment of Recurrent Aphthous Ulceration
To evaluate the efficacy of the product Bismu-Jet ® (bismuth tartrate and sodium, neomycin sulfate and procaine hydrochloride) produced by EMS S / A compared to placebo in reducing the signs and symptoms resulting from UAR in…
- Trial name
- NCT00857688
- Testing
- Bismu-Jet
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil