Clinical trials: Cannabidiol
Cancer
The Use of Cannabidiol in Cancer Patients
Alternative and complementary medicines (MAC) are commonly used by cancer patients to help them to face with anticancer treatment, reduce oncology symptoms and/or anticancer treatment adverse effects, detoxifying the body.
- Trial name
- CANPADIOL (NCT05407298)
- Testing
- Non applicable
- Where
- France
- Volunteers
- 350 people
- Sponsor
- CHU de Reims
Posttraumatic Stress Disorder, Stress Disorders, Post-Traumatic
Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder
The primary goal of this pilot project is to demonstrate the safety and feasibility of using Cannabidiol (CBD) in combination with standard of care prolonged exposure (PE) psychotherapy to reduce PTSD symptoms.
- Trial name
- NCT05132699
- Testing
- Cannabidiol (CBD) oral solution, Massed Prolonged Exposure (mPE)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Autism Spectrum Disorder
Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder
This study investigates brain response to single acute dose of cannabidiol, cannabidivarin, and placebo in healthy men with and without autism spectrum disorder
- Trial name
- NCT03537950
- Testing
- PLC, CBD, CBDV
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- King's College London
CBD, Neural Responses
Sex Differences in Neural Response to Cannabidiol
This is a randomized, double-blind, within-subjects, cross-over design to assess neural changes following a single dose of cannabidiol (CBD) (600mg) versus placebo among healthy female volunteers.
- Trial name
- NCT04777643
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Yale University
Multiple Sclerosis, Diabetes
An Observational Post-Marketing Safety Registry of Sativex®
The purpose of this registry is to monitor safety outcomes of patients who are receiving Sativex® for Multiple Sclerosis (MS) spasticity and for off-label indications in the United Kingdom (UK), Germany and Sweden.
- Conditions
- Multiple Sclerosis, Diabetes, Cancer, Neuropathic Pain
- Trial name
- NCT02073474
- Testing
- Sativex®
- Volunteers
- 978 people
- Sponsor
- Jazz Pharmaceuticals
Post Traumatic Stress Disorder
Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder
The overarching objective of the proposed project is to test the clinical efficacy of CBD in the treatment of post-traumatic stress disorder using a rigorous double-blind randomized clinical trial methodology.
- Trial name
- NCT04197102
- Testing
- CBD Isolate, CBD Broad Spectrum
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Texas at Austin
Infantile Spasm
A Study to Assess Cannabidiol Oral Solution With Vigabatrin as Initial Therapy in Participants With Infantile Spasms
The primary purpose of this study was to evaluate the efficacy, safety, and tolerability of Cannabidiol Oral Solution (CBD) as adjunctive therapy with vigabatrin as initial therapy, compared to vigabatrin alone in the treatment…
- Trial name
- NCT03421496
- Testing
- Cannabidiol Oral Solution, Vigabatrin
- Where
- 5 sites in United States
- Volunteers
- 2 people
- Sponsor
- Radius Pharmaceuticals, Inc.
Gastroparesis, Dyspepsia
Efficacy and Safety of Cannabidiol for Gastroparesis and Functional Dyspepsia
Researchers are looking at the effects of a cannabidiol medication on stomach function in people with gastroparesis (a paralyzed stomach) and people with dyspepsia (an upset stomach caused by improper functioning of the stomach's…
- Trial name
- NCT03941288
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Mayo Clinic
Persistent Post Traumatic Headache
nVNS, CBD, and SoC for Persistent Post-Traumatic Headache
Do cannabidiol (CBD) or vagus nerve stimulation reduce the frequency of persistent post-traumatic headache more than traditional oral headache medications?
- Trial name
- NCT07624279
- Testing
- Non-Invasive Vagus Nerve Stimulation, Cannabidiol, Standard of Care
- Where
- 8 sites in United States
- Volunteers
- 80 people
- Sponsor
- American Society of Pain and Neuroscience, Inc.
Anxiety, Generalized Anxiety Disorder
Evaluation of Effects of CBD Products on Anxiety Among U.S. Women
The investigators will conduct a retrospective cohort analysis of a consumer trial conducted by Rae Wellness. The trial took place between October 15, 2020 and December 30, 2020 and involved 1350 U.S.
- Trial name
- NCT05108220
- Testing
- Cannabidiol (CBD)- containing consumer products
- Where
- United States
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Childhood Absence Epilepsy
Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures
The primary purpose of this study is to assess the efficacy of Cannabidiol Oral Solution in the treatment of pediatric participants with treatment-resistant childhood absence seizures.
- Trial name
- NCT03336242
- Testing
- Cannabidiol Oral Solution
- Where
- 11 sites in United States
- Volunteers
- 20 people
- Sponsor
- Radius Pharmaceuticals, Inc.
CBD, Stress
Effects of Cannabidiol on Stress and Nicotine Withdrawal
The purpose of this study is to examine the effect of doses of cannabidiol (CBD) during exposure to stress and nicotine withdrawal in nicotine users.
- Conditions
- CBD, Stress, Nicotine Dependence, Tobacco Smoking
- Trial name
- CREWS (NCT07001930)
- Testing
- Epidiolex
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
Chronic Musculoskeletal Pain, Delayed Onset Muscle Soreness (DOMS)
Real-world Evidence of Cannabinoid for Observed Pain Relief
Chronic muscle pain is one of the most prevalent clinical challenges in sports medicine, significantly affecting training capacity, competitive performance, and quality of life in athletes.
- Trial name
- RECOVER (NCT07733791)
- Volunteers
- 60 people
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia
Myalgia, Muscle Pain
Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with…
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT06405646
- Testing
- Blood CB1, CB2, TRPV-1 concentration measurement
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Cannabis Use Disorder
Evaluation of the Effects of Cannabidiol (CBD) Compared to Delta-9-Tetrahydrocannabinol (THC) and Alprazolam
The purpose of this study is to evaluate the abuse potential of CBD to determine whether it should remain as a Schedule I drug under the Controlled Substances Act, or be recommended for decontrol.
- Trial name
- NCT03398083
- Testing
- THC, Alprazolam, CBD
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorders
CBD, Nutrient Metabolism and Energy Intake
CBD may affect metabolic control and energy intake. However, there is currently little data regarding these specific outcomes in humans.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Lipid Metabolism Disorders, Appetitive Behavior
- Trial name
- NCT05618756
- Testing
- Acute oral CBD supplementation
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Opioid-use Disorder
Cannabidiol on Reward- and Stress-related Neurocognitive Processes in Individuals With Opioid Use Disorder
The purpose of this study is to determine the impact of cannabidiol on reward- and stress-related neurocognitive processes among individuals with opioid use disorder on buprenorphine or methadone treatment.
- Trial name
- NCT04982029
- Testing
- Cannabidiol 100 MG/ML [Epidiolex]
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital
Epileptic Encephalopathy
Cannabidiol in Children With Refractory Epileptic Encephalopathy
This study will assess the safety and tolerability of a cannabidiol-enriched Cannabis Herbal Extract in a small group of children with refractory epileptic encephalopathy.
- Trial name
- CARE-E (NCT03024827)
- Testing
- CanniMed® 1:20
- Where
- 4 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Saskatchewan
Interstitial Cystitis, Bladder Pain Syndrome
The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)
This study seeks to exploit bladder cannabidiol receptors as a therapeutic drug target by conducting a double-masked, placebo-controlled randomized trial evaluating the effects of vaginal hemp cannabidiol (CBD) suppositories on…
- Trial name
- CHRONIC (NCT04349930)
- Testing
- Cannabidiol vaginal suppository
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Posttraumatic Stress Disorder
Effects of CBD Oil on Memory Reconsolidation and Trauma-Related Symptoms
The purpose of this study is to investigate the effects of cannabidiol (CBD) broad-spectrum oil on memory reconsolidation (memory storage) and trauma-related symptoms in trauma-exposed individuals after exposure to a trauma…
- Trial name
- NCT05892276
- Testing
- Trauma Memory Reactivation, Cannabidiol (CBD) Broad-Spectrum Oil
- Where
- United States
- Sponsor
- University of Texas at Austin