Clinical trials: Cannabidiol
Drug Resistant Epilepsy
Study of Cannabidiol for Drug-Resistant Epilepsies
The purpose of this study is to determine if cannabidiol is safe and effective at different doses as an additional treatment for pediatric drug-resistant epilepsy.
- Trial name
- NCT03014440
- Testing
- Cannabidiol
- Sponsor
- Eric Marsh, MD
Pain, Sleep Disturbance
Radicle ACES: A Study of Commercially Available CBD Used in the Real-world Setting
A randomized, open-label study of commercially available, orally ingestible, Cannabidiol (CBD) products used in the real-world setting for pain, sleep, and anxiety.
- Conditions
- Pain, Sleep Disturbance, Anxiety
- Trial name
- RWE-ACES (NCT05003882)
- Testing
- Commercially available, orally ingestible CBD product
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Generalized Anxiety Disorder, Social Anxiety Disorder
Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study
This proposed study aims to evaluate the efficacy of a daily oral cannabinoid oil preparation in treating symptoms of DSM-5 anxiety disorders, using a two-arm, 8-week randomized, placebo-controlled trial in adults aged 21-65…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT04569760
- Testing
- 50:2 mg(CBD:THC)/ml - Cannabinoid Oil Oral Preparation- titrated as tolerated up to a maximum 8mls twice daily (200 mg- 800 mg total dose)
- Where
- Canada
- Sponsor
- McMaster University
Cannabis Use
Effect of Cannabidiol (CBD) on Vision and Driving
The use of cannabis with ∆9-tetrahydrocannabinol (THC) content has been shown to have negative effects on vision and driving. The use of other cannabinoids, such as cannabidiol (CBD), which is not attributed with a psychoactive…
- Trial name
- NCT06322303
- Testing
- CBD 15%, CBD 30%
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Epilepsy
Treatment of Drug Resistant Epilepsy
The main goal of this study is to provide treatment with cannabidiol (CBD) to children with drug resistant epilepsy through a Physician Expanded Access Investigation New Drug protocol.
- Trial name
- Cannabidiol (NCT02461706)
- Testing
- cannabidiol, Blood Test
- Where
- 2 sites in United States
- Sponsor
- University of Florida
Parkinson Disease
Clinical Trial with Cannabidiol (Kanbis®) for Parkinson Disease Symptoms
Parkinson disease (PD) is a chronic, progressive neurodegenerative disorder characterized by clinical motor and non-motor symptoms. Knowing the potential benefits has led to the use of cannabis as an alternative therapy.
- Trial name
- CBD-EP-2 (NCT06629389)
- Testing
- Cannabidiol 100 mg/ml, cannabidiol 300 mg/ml, Cannabidiol 400 mg/ml
- Where
- Argentina
- Volunteers
- 88 people
- Sponsor
- Laboratorio Elea Phoenix S.A.
CBD Pharmacokinetics, Healthy Participants
A Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions
Cannabidiol (CBD), derived from the Cannabis sativa plant, is being investigated for its potential health benefit without the psychoactive properties and adverse reactions that arise from the use of delta-9-tetrahydrocannabinol…
- Trial name
- NCT06578455
- Testing
- Cannabidiol (CBD) Powder, Cannabidiol 100 MG/ML [Epidiolex]
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Healthy Volonteers
Safety and Pharmacokinetics of Vaped Cannabis in Healthy Volunteers
The primary objective of this study was to evaluate the pharmacokinetics (PK) of THC, 11-OH-THC and CBD following a single inhaled dose of PPP001 administered by vaporization.
- Trial name
- NCT04461756
- Testing
- PPP001
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Tetra Bio-Pharma
Anxiety, Generalized Anxiety Disorder
Use of CBD in the Treatment of Anxiety
This study will examine the doses, safety, and test the preliminary efficacy of hemp-derived CBD product for improving anxiety symptoms and sleep disturbances among individuals with anxiety.
- Conditions
- Anxiety, Generalized Anxiety Disorder, Sleep Problems
- Trial name
- NCT06672666
- Testing
- Hemp Derived Cannabidiol Extract
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Knee Osteoarthritis, CBD
The Use of Cannabinoid Patch for Knee Osteoarthritis
This randomized, double-blind 2-arm parallel group study to determine the efficacy of a cannabinoid (CBD) patch on reducing pain in patients with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, CBD, Osteoarthritis
- Trial name
- NCT04412837
- Testing
- Topical CBD Patch
- Where
- United States
- Sponsor
- Northwell Health
HIV-1-infection
Cannabis Use, Cognition, and the Endocannabinoid System in HIV
Understanding how co-morbidities in persons with HIV (PWH) such as substance use affect risk-taking, decision-making, and other cognitive behaviors is important given implications for everyday functioning and transmission risk.
- Trial name
- NCT04883255
- Testing
- 10 mg Δ9-tetrahydrocannabinol (THC), 600 mg cannabidiol (CBD)
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Chronic Pain, Opioid Use Disorder
Cannabidiol in Opioid Use Disorder and Chronic Pain With Buprenorphine
This is a randomized, placebo-controlled, crossover human laboratory study investigating the dose-dependent safety and acute effects of Cannabidiol (CBD) on measures of pain and opioid craving in outpatients with opioid use…
- Trial name
- NCT07886606
- Testing
- 400 mg Cannabidiol, 800 mg Cannabidiol, 1200 mg Cannabidiol
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Yale University
Cancer of Pancreas, Cancer of Liver
A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies
A Randomized, Double-Blind, Placebo-Controlled, Parallel, Multi-Center Study to Assess the Efficacy of BRCX014 Combined with Standard-Of-Care Treatment in Subjects with Glioblastoma Multiforme, Multiple Myeloma, and GI…
- Conditions
- Cancer of Pancreas, Cancer of Liver, Cancer of Rectum, Cancer of Colon
- Trial name
- NCT03607643
- Testing
- Cannabidiol, Bortezomib, Leucovorin
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Leaf Vertical Inc.
PTSD
Safety and Efficacy of Cannabidiol (CBD) for Symptoms of PTSD in Adults
Post-traumatic stress disorder (PTSD) is a psychiatric disorder than may develop following a traumatic event including serious incidents, natural or human-caused disasters, violence, death of a loved one, receipt of traumatic…
- Trial name
- NCT05269459
- Testing
- Cannabidiol Administered as Nantheia ATL5
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Nebraska
Breast Cancer Female
Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.
Investigating the potential role of a novel quadrate combination therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic acid and Cannabidiol ( selective cyp 26 inhibitor) for treating early breast cancer.
- Trial name
- NCT05016349
- Testing
- All trans-retinoic acid, 13-Cis Retinoic Acid plus Tocopherol, Mifepristone
- Volunteers
- 160 people
- Sponsor
- Mahmoud Ramadan mohamed Elkazzaz
Healthy
Cannabidiol Effects on Cardiovascular System and Exercise Responses
To identify the autonomic effects of recreationally-relevant doses of cannabidiol (CBD) in an older population, and to evaluate the effect of CBD on exercise performance and recovery.
- Trial name
- NCT05232123
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Castleton University
Plantar Fasciitis
A Double-Blinded Study on Rapid and Sustained Pain Relief Topical Cannabidiol for Plantar Fasciitis
This prospective, double-blinded, placebo-controlled study evaluates the efficacy of a 6000 mg transdermal CBD cream in adults with plantar fasciitis. Fifty participants will apply either CBD or placebo once daily for one month.
- Trial name
- NCT07776405
- Testing
- transdermal CBD cream (Tolcylen®, Marlinz Pharma)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Anorexia Nervosa
Role of CBD in Regulating Meal Time Anxiety in Anorexia Nervosa
No studies of cannabidiol (CBD) have focused on Anorexia Nervosa (AN). Dose, side effects, tolerability, acceptability of pure CBD in AN must be established.
- Trial name
- NCT04878627
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Osteoarthritis, Knee
CBD for Knee Osteoarthritis
Osteoarthritis is a disease that affects millions of Americans and is the leading cause of persistent pain and physical disability in the older adult population.
- Trial name
- SLACK-OA (NCT06414473)
- Testing
- Cannabidiol (CBD) Extract
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Graft Versus Host Disease
Cannabidiol for Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Stem Cell Transplantation
Graft versus host disease (GVHD) is one of the major causes of death in patients undergoing allogeneic hematopoietic cell transplantation.
- Trial name
- NCT01385124
- Testing
- Oral Cannabidiol
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rabin Medical Center