Clinical trials: Cannabidiol
Endometriosis, CBD
Cannabidiol and Management of Endometriosis Pain
The investigators are looking to conduct a study looking at the effects of cannabidiol (CBD) in patients with endometriosis. It is believed that CBD will improve both pain and quality of life.
- Conditions
- Endometriosis, CBD, Pelvic Pain
- Trial name
- NCT04527003
- Testing
- Cannabidiol (CBD) Extract, Norethindrone Acetate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Milton S. Hershey Medical Center
Cannabis Use Disorder
A Study of Cannabidiol in Young Adult Cannabis Users
The investigators will study the harm-reducing effect of hemp-derived CBD in non-treatment-seeking emerging adults who use cannabis regularly.
- Trial name
- NCT06569394
- Testing
- Broad Spectrum Cannabidiol (bsCBD) 400 mg
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Anxiety and Fear
Impact of CBD-Rich Oil on Aversive Memory Reconsolidation
The purpose of this study is to test whether cannabidiol (CBD) rich hemp extract oil can interfere with the reconsolidation (storage) of pathological fear memory in humans.
- Trial name
- NCT04726475
- Testing
- Interoceptive Aversive Memory Reactivation, Cannabidiol (CBD)-Rich Broad Spectrum Hemp Extract Oil
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Texas at Austin
Neurodevelopmental Disorders With Severe Self-injuries
Efficacy of Cannabidiol in the Management of Self-injuries in Children and Adolescents With Severe Neurodevelopmental Disorders.
Self-injuries includes repetitive actions directed at oneself, such as biting, hitting, hitting one's head or limbs, slapping oneself, pulling one's hair, or hitting oneself in the eyes, which can lead to severe injury.
- Trial name
- CBD-SIB (NCT07564245)
- Testing
- Cannabidiol
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Feeding
Cannabidiol Into Breastmilk
Really few data published to date on the passage of CBD into breast milk. The investigators known that 17.5 percent of the French human being between 18 and 34 years old consume CBD and among this, nearly half are women.
- Trial name
- CBD-ALLT (NCT06589258)
- Testing
- Assessing maternal and lactational plasma CBD uptake at different stages of breastfeeding
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Endometriosis, Pelvic Pain
Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND)
The objective of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabis extract in women with endometriosis who have already undergone hormonal…
- Trial name
- DREAMLAND (NCT05670353)
- Testing
- Cannabis Derivatives, Hormonal Contraceptive Agents
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Contraception
Cannabidiol and Oral Contraceptive Pills: Exploring a Drug-Drug Interaction
The purpose of this study is to assess how Cannabidiol (CBD) impacts the effectiveness of oral contraceptive (birth control) pills and if CBD changes the possible side effects of birth control pills when CBD and birth control…
- Trial name
- NCT04396730
- Testing
- Cannabidiol Oil, Combined oral contraceptive pill
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Pain
PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
This study is a clinical trial of a high-cannabidiol (CBD) sublingual product compared to placebo for 9 weeks in patients with chronic pain conditions.
- Trial name
- NCT03984565
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Staci Gruber, Ph.D.
Epilepsy, Dravet Syndrome
A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)
To evaluate the safety and pharmacokinetics (PK) of multiple doses of GWP42003-P compared with placebo in children with Dravet syndrome.
- Trial name
- NCT02091206
- Testing
- GWP42003-P 5 mg/kg/day Dose, GWP42003-P 10 mg/kg/day Dose, GWP42003-P 20 mg/kg/day Dose
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 34 people
- Sponsor
- Jazz Pharmaceuticals
Cancer
The Use of Cannabidiol in Cancer Patients
Alternative and complementary medicines (MAC) are commonly used by cancer patients to help them to face with anticancer treatment, reduce oncology symptoms and/or anticancer treatment adverse effects, detoxifying the body.
- Trial name
- CANPADIOL (NCT05407298)
- Testing
- Non applicable
- Where
- France
- Volunteers
- 350 people
- Sponsor
- CHU de Reims
Forehead; Wound
Topical CBD Scar Outcomes Study
The purpose of this study is to find out what effects (good and bad) that cannabidiol (CBD) has on scar healing and appearance in patients who have undergone paramedian forehead flap reconstruction.
- Trial name
- TOPSCAR (NCT05650697)
- Testing
- Group 1 cannabidiol (CBD) with silicone ointment, Group 2 silicone patch
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Oklahoma
Healthy Volunteers, Modeling Psychosis
Gene-Environment-Interaction: Influence of the COMT Genotype on the Effects of Different Cannabinoids - a PET Study
The study evaluates the gene-environment interaction of the COMT-genotype on the effects of the phytocannabinoids delta-9-tetrahydrocannabinol, cannabidiol or a combination of both on induction of psychotic symptoms…
- Trial name
- NCT02492074
- Testing
- Delta-9-tetrahydrocannabinol, Cannabidiol
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
SARS-CoV2
CANnabiDiol for CoviD-19 pATiEnts With Mild to Moderate Symptoms
The aim of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabidiol (CBD - 300 mg a day) in patients infected with SARS-CoV-2.
- Trial name
- CANDIDATE (NCT04467918)
- Testing
- Cannabidiol
- Where
- 2 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Spasms, Infantile
Cannabidiol Oral Solution for Treatment of Refractory Infantile Spasms
Infantile Spasms (IS) is a diagnosis described as a fairly rare and terrible form of epilepsy that usually strikes children in the first year of life. There is a great need for safe and effective therapies in the treatment of IS.
- Trial name
- NCT02551731
- Testing
- Cannabidiol Oral Solution
- Where
- 4 sites in United States
- Volunteers
- 9 people
- Sponsor
- INSYS Therapeutics Inc
Graft Versus Host Disease
Safety and Efficacy of Cannabidiol for Grade I/II Acute Graft Versus Host Disease (GVHD) After Allogeneic Stem Cell Transplantation
Graft versus host disease (GVHD) is one of the major causes of death in patients undergoing allogeneic hematopoietic stem cell transplantation.
- Trial name
- NCT01596075
- Testing
- Cannabidiol
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
Focal Seizures
A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
Cannabidiol oral solution (CBD-OS) is approved in the US for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or Tuberous sclerosis complex (TSC) in patients 1 year of age and older.
- Trial name
- NCT07233239
- Testing
- CBD-OS
- Where
- 24 sites in United States
- Volunteers
- 100 people
- Sponsor
- Jazz Pharmaceuticals
Pain, Postoperative, Opioid Use
Cannabidiol for Bilateral Total Knee Arthroplasty
In light of the opioid epidemic and evidence suggesting that cannabis may be opioid-sparing, we are in a unique position to conduct a novel, high-impact study that would set the stage for future RCTs examining the effects of a…
- Conditions
- Pain, Postoperative, Opioid Use, Knee Osteoarthritis
- Trial name
- NCT04749628
- Testing
- cannabidiol, Ora-sweet SF
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Hospital for Special Surgery, New York
Parkinson's Disease (PD)
Full-Spectrum Cannabidiol Oil for Anxiety and Depressive Symptoms in Parkinson's Disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as bradykinesia, rigidity, and tremor.
- Trial name
- COOPERATE (NCT07651930)
- Testing
- Full-spectrum Cannabidiol (CBD) oil
- Where
- Poland
- Volunteers
- 27 people
- Sponsor
- Medical University of Warsaw
Social Anxiety Disorder
Cannabidiol Effects on Fear Extinction in Social Phobia
The investigators will randomly assign participants with social anxiety disorder to receive oral cannabidiol (CBD) or placebo. Participants will undergo a fear conditioning and extinction trial, and the investigators will examine…
- Trial name
- NCT06123702
- Testing
- Fear extinction, Cannabidiol Cap/Tab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hartford Hospital
Childhood Absence Epilepsy
Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures
The primary purpose of this study is to assess the efficacy of Cannabidiol Oral Solution in the treatment of pediatric participants with treatment-resistant childhood absence seizures.
- Trial name
- NCT03336242
- Testing
- Cannabidiol Oral Solution
- Where
- 11 sites in United States
- Volunteers
- 20 people
- Sponsor
- Radius Pharmaceuticals, Inc.