Clinical trials: Cannabidiol
Schizophrenia
A Four-week Clinical Trial Investigating Efficacy and Safety of Cannabidiol As a Treatment for Acutely Ill Schizophrenic Patients
Schizophrenia is a heterogeneous mental disorder that affects one percent of the world's population. Current antipsychotics are only partially effective, and their use is often associated with serious side effects.
- Trial name
- NCT02088060
- Testing
- Cannabidiol, Olanzapine
- Where
- 6 sites in Denmark, Germany
- Volunteers
- 150 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Irritable Bowel Syndrome
The Effect of CanChew® Cannabidiol (CBD) Containing Chewing Gum on Irritable Bowel Syndrome
Rationale: IBS is the most common functional gastrointestinal disorder with a prevalence worldwide ranging from 9-23%. Complaints include abdominal discomfort or pain and altered bowel habits.
- Trial name
- NCT03003260
- Testing
- CBD chewing gum
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Wageningen University
Tooth Decay
This Research Study Examines the Effects of Cannabidiol-infused Candy on Reducing the Bacteria Causing Tooth Decay, When Comparing it to a Sugar Free Candy on Adults.
The goal of this clinical trial is to compare the effect of CBD candy versus sugar free candy on reducing the number of bacteria causing tooth decay, in adults The main question is to see whether CBD have any effect on reducing…
- Trial name
- NCT06301113
- Testing
- CBD infused candy, Sugar free Candy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- West Coast University
Perceptions
Consumer Perceptions of Cannabidiol (CBD) Health Claims
Over 46 million US adults report use of cannabidiol (CBD), primarily to treat medical ailments. The growing CBD market spans the range of products that the US Food and Drug Administration (FDA) regulates including drugs, dietary…
- Trial name
- CBD (NCT06069713)
- Testing
- CBD advertisements
- Where
- United States
- Volunteers
- 3,504 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cosmetics; Eczema
Effect of an Emollient Cream Containing 0.5% Cannabidiol and 1% Hemp Oil in the Hydration and Erythema of the Skin
This research seeks to evaluate the short (i.e., after single application) and long-term (i.e., after periodic application) hydrating effect of a topical preparation containing CBD and hemp oil on the skin of the volar forearm as…
- Trial name
- Celosia (NCT04045314)
- Testing
- Topical moisturizer
- Where
- Colombia
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Avicanna Inc
Sleep, Anxiety
Cannabidiol and Older Adult Cannabis Users
Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior.
- Conditions
- Sleep, Anxiety, Depression, Pain
- Trial name
- QUARTz (NCT06290063)
- Testing
- fsCBD Cannabidiol, bsCBD Cannabidiol
- Where
- United States
- Volunteers
- 385 people
- Sponsor
- University of Colorado, Boulder
Atopic Dermatitis
Comparison of JW-100 and EUCRISA for the Treatment of Atopic Dermatitis
To compare the efficacy of a JW-100 cream with active control (commercially available as EUCRISA®, Pfizer) for the treatment of atopic dermatitis (AD) in adult patients with mild to moderate AD measured with the Investigator's…
- Trial name
- NCT05016284
- Testing
- JW-100, Eucrisa
- Where
- Brazil
- Sponsor
- Applied Biology, Inc.
Epilepsy
A Randomized Controlled Trial to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol
This trial consists of 2 parts: a double-blinded phase and an open-label extension phase. The blinded phase only will be described in this record.
- Trial name
- NCT02565108
- Testing
- GWP42003-P 20 mg/kg/Day Dose, Clobazam
- Where
- 6 sites in Spain, United Kingdom
- Volunteers
- 20 people
- Sponsor
- Jazz Pharmaceuticals
Fragile X Syndrome
Effect of CBD on the Brain
This proposal focuses on the therapeutic relevance of the endocannabinoid (eCB) system for the treatment of Fragile-X syndrome (FXS), the primary hereditary cause of autism spectrum disorder (ASD).
- Trial name
- NCT06261450
- Testing
- CBD Oral Solution (eCBD system Target)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
CBD, Hand Osteoarthritis
Is Topical CBD Effective in Treating Thumb Joint Arthritis
Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy.
- Trial name
- NCT04611347
- Testing
- CBD, Shea Butter
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Sturge-Weber Syndrome
Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome
The purpose of this study is to determine the tolerability and optimal dose of cannabidiol (CBD) as an simultaneous treatment in children and young adults with Sturge-Weber syndrome (SWS) and drug resistant epilepsy.
- Trial name
- NCT02332655
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Anne Comi, MD
Knee Arthritis
Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis
The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) can lessen pain, improve function, and improve patient satisfaction in cases of knee osteoarthritis.
- Trial name
- NCT05020028
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Restless Leg Syndrome
Tolerability and Efficacy of CBD Extract for RLS Treatment
This study plans to learn more about the safety and tolerability of high Cannabidiol (CBD) cannabis extract (BRC-002) for use in Idiopathic Restless Legs Syndrome.
- Trial name
- NCT07224932
- Testing
- BRC-002, Placecbo
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
PTSD
Cannabidiol and Prolonged Exposure
The trial will include a randomized control trial to evaluate the efficacy of using Cannabidiol (CBD), a non-intoxicating cannabinoid, as an adjunctive to Prolonged Exposure therapy (PE).
- Trial name
- CBD-PE (NCT03518801)
- Testing
- Prolonged Exposure, Cannabidiol
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Healthy
Cannabidiol and Focus Study (CBD-Focus)
Cannabidiol (CBD), a non-psychoactive hemp derivative, is an attractive therapeutic target, and is most supported by the scientific community as an antiepileptic, anxiolytic, and antipsychotic.
- Trial name
- CBD-Focus (NCT05189275)
- Testing
- Daily Beverage Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Epilepsy, Dravet Syndrome
Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)
To investigate the potential antiepileptic effects of cannabidiol (GWP42003-P) in children and young adults with Dravet syndrome.
- Trial name
- NCT02091375
- Testing
- GWP42003-P 20 mg/kg/day Dose
- Where
- 22 sites in United States, France and 2 more
- Volunteers
- 120 people
- Sponsor
- Jazz Pharmaceuticals
Chronic Pain
PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
This study is a clinical trial of a high-cannabidiol (CBD) sublingual product compared to placebo for 9 weeks in patients with chronic pain conditions.
- Trial name
- NCT03984565
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Staci Gruber, Ph.D.
Osteoarthritis, Knee
CBD for Knee Osteoarthritis
Osteoarthritis is a disease that affects millions of Americans and is the leading cause of persistent pain and physical disability in the older adult population.
- Trial name
- SLACK-OA (NCT06414473)
- Testing
- Cannabidiol (CBD) Extract
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Social Anxiety Disorder
Cannabidiol Effects on Fear Extinction in Social Phobia
The investigators will randomly assign participants with social anxiety disorder to receive oral cannabidiol (CBD) or placebo. Participants will undergo a fear conditioning and extinction trial, and the investigators will examine…
- Trial name
- NCT06123702
- Testing
- Fear extinction, Cannabidiol Cap/Tab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hartford Hospital
Alexithymia, HIV
Role of CBD in Improving Alexithymia
Given the treatments that are available today for HIV disease, people living with HIV (PLWH) can generally expect good medical outcomes.
- Trial name
- ACBD (NCT05832281)
- Testing
- Purysis CBD
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Diego