Clinical trials: Cannabis Abuse
Dual Diagnosis
Cannabidiol for Treatment of Non-affective Psychosis and Cannabis Use
This trial examines the efficacy of cannabidiol (CBD) versus risperidone for treatment of psychosis in patients with non affective-psychosis and lifetime use of cannabis.
- Trial name
- NCT04105231
- Testing
- Cannabidiol, Risperidone
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Lone Baandrup
Pain, Hyperalgesia
Analgesic Efficacy of Smoked Cannabis
The purpose of this study is to determine whether or not inhaled marijuana displays any pain-relieving properties on experimentally-induced pain.
- Trial name
- NCT00241579
- Testing
- Smoked Cannabis
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Center for Medicinal Cannabis Research
Generalized Anxiety Disorder, Social Anxiety Disorder
Cannabidiol for the Treatment of Anxiety Disorders: An 8-Week Pilot Study
This proposed study aims to evaluate the efficacy of daily Cannabidiol (CBD) Oil Capsules in treating symptoms of DSM-5 anxiety disorders, using a two-arm, 8-week randomized, placebo-controlled trial in adults aged 21-65 years.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03549819
- Testing
- Cannabidiol (CBD) Oil Capsules, Sunflower Lecithin Oil in Capsule
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Cannabinoid Hyperemesis Syndrome
Capsaicin for the Treatment of Cannabinoid Hyperemesis Syndrome
This study aims to determine if capsaicin cream offers symptomatic relief to patients suffering from Cannabinoid Hyperemesis Syndrome (condition that leads to repeated and severe bouts of vomiting).
- Trial name
- NCT04283292
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Alcoholic Intoxication, Automobile Accident
Responsible Marijuana Sales Practices to Reduce the Risk of Selling to Intoxicated Customers
The new recreational marijuana markets are contributing to polysubstance-impaired driving and other harms, especially when marijuana is used in combination with alcohol, by selling marijuana to obviously-intoxicated customers.
- Conditions
- Alcoholic Intoxication, Automobile Accident, Cannabis
- Trial name
- NCT06235632
- Testing
- Policy and Training Intervention, Usual and Customary Policy and Training (UC-PT) (Control) Condition
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Klein Buendel, Inc.
Pain, Abuse, Drug
Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia
The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-liability effects of a sub-threshold dose of a commonly used analgesic.
- Trial name
- NCT03679949
- Testing
- Oxycodone, Cannabis (THC:CBD = ~ 1:0), Cannabis (THC:CBD = ~ 0:1)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Cannabis, Post Traumatic Stress Disorder
Nabilone in Cannabis Users With PTSD
Despite the prevalence of cannabis use among the PTSD population and self-reports that it is used to help cope with PTSD symptoms, the direct effects of cannabis on PTSD symptomology are unknown.
- Trial name
- NCT03251326
- Testing
- Nabilone, Cannabis, Propranolol
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- New York State Psychiatric Institute
Cannabis Dependence, Cannabis Withdrawal
Clinical and Neurobiological Effects of Cannabis Dependence in Young Adults
The purpose of this study is to find out more about cognitive functioning in people who are cannabis dependent, relative to people who do not use cannabis, and how their brains process information after one month of not using…
- Trial name
- SCCAN (NCT00656487)
- Testing
- rimonabant
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Scripps Research Institute
Cannabis Use
Survey on the Place of Community Pharmacists in the Detection of Cannabis Use: a Student's Point of View
The objective of this survey will be to evaluate the perception by the students (except for medical students, pharmacies) of community pharmacists concerning the management of cannabis consumption.
- Trial name
- CANNACY (NCT03167021)
- Testing
- Survey
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071975
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Marijuana Abuse, Attention Deficit Disorder With Hyperactivity
Atomoxetine Treatment for ADHD and Marijuana Dependence
The aim of the study is to determine if atomoxetine treatment combined with motivational enhancement therapy is effective in reducing marijuana use in adult individuals with attention-deficit hyperactivity disorder and marijuana…
- Trial name
- NCT00360269
- Testing
- Atomoxetine, Motivational enhancement therapy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Medical University of South Carolina
Marijuana Abuse
Efficacy of Contingency Management in the Treatment of Adolescents With Cannabis Use Disorders
Cannabis use among Spanish adolescents has been increasing in the last decade. It has been related to poor school achievement, delinquency, substance use and psychiatric disorders.
- Trial name
- NCT00878852
- Testing
- Standard treatment, Standard Treatment Plus Contingency Management Program
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Clinic of Barcelona
Opioid Use, Marijuana
Does Medical Cannabis Reduce Opioid Use in Adults With Pain
The study will examine how medical cannabis use affects opioid analgesic use. This landmark study will be among the first to examine the effect of medical cannabis with different THC/CBD (Tetrahydrocannibinol/Cannabidiol) content…
- Conditions
- Opioid Use, Marijuana, Chronic Pain
- Trial name
- ReLeaf-E (NCT04308148)
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- Albert Einstein College of Medicine
Thromboangiitis Obliterans, Atheromatous Arteritis
ADDICTAO: Psychological and Addictive Profile of Patients With Buerger's Disease
Background: Buerger's disease (thromboangiitis obliterans or TAO) is a rare disease (1/ 10 000) characterized by the development of segmental thrombotic occlusions of the medium and small arteries of the extremities.
- Trial name
- ADDICTAO (NCT01064206)
- Where
- 16 sites in France
- Volunteers
- 224 people
- Sponsor
- University Hospital, Lille
Cannabis Dependence, Cannabis Withdrawal
Gabapentin Treatment of Cannabis Dependence
This is a clinical study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.
- Conditions
- Cannabis Dependence, Cannabis Withdrawal, Cognitive Deficits
- Trial name
- NCT00974376
- Testing
- gabapentin 1200mg/day, Manual-guided behavioral counseling
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The Scripps Research Institute
Cannabis
Detection of Cannabis Impairment With ISBRG's SpotLight-THC
Subjects will participate in a 2-visit study protocol in which they will be administered cannabis of pre-determined concentrations and asked to complete a simulated drive in a driving simulator.
- Trial name
- NCT05276232
- Testing
- Cannabis(THC) inhaled
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ISBRG Corp
Opioid Use Disorder
Reducing Pain and Opioid Use With CBD
This is a double-blind, placebo-controlled, parallel group study designed to assess the tolerability and efficacy of fsCBD and bsCBD, compared to a placebo control, to reduce opioid use, anxiety, and pain and improve sleep and…
- Trial name
- NCT05299944
- Testing
- Cannabidiol
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of Colorado, Denver
Knee Osteoarthritis
Cannabinoids vs. Placebo on Persistent Post-surgical Pain Following TKA: A Pilot RCT
Each year, approximately 75,000 Canadians undergo knee replacement surgery, and up to 25% develop persistent post-surgical pain.
- Trial name
- NCT03825965
- Testing
- MPL-001 (CBD: THC 25:1)
- Where
- 2 sites in Canada
- Volunteers
- 39 people
- Sponsor
- McMaster University
Cannabis Dependence, Substance Withdrawal Syndrome
Lithium Cannabis Withdrawal Study
This trial will examine the efficacy of lithium in providing symptomatic relief from the withdrawal discomfort experienced by some dependent users of cannabis on cessation of regular use.
- Trial name
- NCT00114439
- Testing
- Lithium carbonate
- Where
- Australia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sydney South West Area Health Service
Cocaine Dependence, Cannabis Dependence
Risk Perception in Drug-Dependent Adults With and Without Schizophrenia
Background: Several studies of risk perception have demonstrated a common bias known as unrealistic optimism, in which individuals feel they are less likely than other people to experience unpleasant or harmful events in their…
- Conditions
- Cocaine Dependence, Cannabis Dependence, Schizophrenia
- Trial name
- NCT01031563
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute on Drug Abuse (NIDA)