Clinical trials: Cannabis Abuse
Schizophrenia, Cannabis Use Disorder
Impact of tDCS on Cannabis Craving in Schizophrenia
This study aims to evaluate the tDCS's impact on cannabis craving in patients with schizophrenia and cannabis addiction disorder.
- Trial name
- tCCS (NCT05784961)
- Testing
- tDCS
- Where
- 2 sites in France
- Volunteers
- 138 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Lean Body Mass, Cannabis
The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
An intervention study on the effect of cannabidiol on lean body mass in cancer patients receiving chemotherapy, at the department of Clinical Oncology at Zealand University Hospital, Roskilde, Denmark.
- Conditions
- Lean Body Mass, Cannabis, Cancer, Nausea
- Trial name
- NCT04585841
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Copenhagen
Cannabis, HIV
Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
This study applies a hypothesis-driven approach to examine the effects of chronic marijuana use on HIV-associated inflammation and its subsequent impacts on central nervous system function, with the goal of identifying the…
- Conditions
- Cannabis, HIV, Inflammation, Cognition
- Trial name
- CHI (NCT04810858)
- Testing
- Multimodal, multi-parametric MRI, Immune and cytokine profiling, Neuropsychological testing
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep
Cannabis Association With Sleep Study
The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.
- Trial name
- CaSS (NCT06982950)
- Testing
- Manipulation of Sleep Duration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Driving Impaired, Cognitive Impairment
Dose-response of Cannabis and Driving
Epidemiological studies have established a link between collisions while driving and cannabis use. With the changing legal landscape around cannabis, there is much interest in determining per se limits of cannabis while driving.
- Conditions
- Driving Impaired, Cognitive Impairment, Abuse Cannabis
- Trial name
- NCT03656029
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Psychosis, Cannabis Use Disorder
Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis (CCP) Intervention for Cannabis Use Reduction/Cessation in Patients With First Episode Psychosis (FEP)
People suffering from psychosis who use cannabis experience more relapses, long and compulsory admissions, with huge costs to the individual, families and health services.
- Conditions
- Psychosis, Cannabis Use Disorder, First Episode Psychosis (FEP)
- Trial name
- CCP RCT (NCT07245212)
- Testing
- CCP Intervention
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- King's College London
Cancer
Cannabis Use and Outcomes in Black and White Patients With Cancer
The goal of the observational study is to learn how black and white patients with solid tumor cancer use cannabis, opioids and tobacco.
- Trial name
- C4C (NCT06037681)
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- State University of New York at Buffalo
Cannabis, Memory
Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 4
This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users.
- Conditions
- Cannabis, Memory, Electroencephalography
- Trial name
- COBRA 4 (NCT07679581)
- Testing
- Cannabis (smoked flower)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- L. Cinnamon Bidwell
Marijuana Abuse
Effects of Stress and Drug-cue Exposure (SCM)
The purpose of the proposed study to examine the links among stress, craving for marijuana, and marijuana reminders, or "cues". In this study, an agent called yohimbine will be used to produce stress-like responses.
- Trial name
- NCT03154567
- Testing
- Yohimbine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wayne State University
Opioid Use Disorders, Cannabis Use
Cannabis and Opioid Use Disorder, Study 2
This inpatient study enrolls healthy individuals who have opioid use disorder. Participants live at the University of Kentucky Hospital for approx. 6 weeks.
- Trial name
- NCT07661446
- Testing
- Inhaled Cannabis, Intranasal Opioid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Kentucky
Cannabis, Youth Drinking
Development and Evaluation of HighAlert
In Canada, youth ages 16-24 have the highest rates of cannabis use, impaired driving, and express the least concern for driving under the influence of cannabis (DUIC).
- Trial name
- NCT06098573
- Testing
- High Alert, Information condition, No contact
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- Western University, Canada
Neuropathic Pain
Effects of Smoked Marijuana on Neuropathic Pain
To determine if smoking marijuana will reduce neuropathic pain without causing too much drowsiness or feeling "too dopey".
- Trial name
- NCT00254761
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Center for Medicinal Cannabis Research
Generalized Anxiety Disorder, Social Anxiety Disorder
Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study
This proposed study aims to evaluate the efficacy of a daily oral cannabinoid oil preparation in treating symptoms of DSM-5 anxiety disorders, using a two-arm, 8-week randomized, placebo-controlled trial in adults aged 21-65…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT04569760
- Testing
- 50:2 mg(CBD:THC)/ml - Cannabinoid Oil Oral Preparation- titrated as tolerated up to a maximum 8mls twice daily (200 mg- 800 mg total dose)
- Where
- Canada
- Sponsor
- McMaster University
Cannabis Use
Effect of Cannabidiol (CBD) on Vision and Driving
The use of cannabis with ∆9-tetrahydrocannabinol (THC) content has been shown to have negative effects on vision and driving. The use of other cannabinoids, such as cannabidiol (CBD), which is not attributed with a psychoactive…
- Trial name
- NCT06322303
- Testing
- CBD 15%, CBD 30%
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Healthy Adult Participants
Evaluation of BRC-002 Safety, Tolerability, Pharmacokinetics, and Food Effects in Healthy Participants
This study will evaluate the safety and tolerability of BRC-002, an investigational botanical drug from cannabis, in healthy adults.
- Trial name
- NCT07699120
- Testing
- BRC-002
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Biopharmaceutical Research Company
Schizophrenia, Cannabis Dependence, Continuous
Effect of Motivational Therapy on Schizophrenia With Cannabis Misuse
Schizophrenia is a severe mental illness with a lifetime morbidity risk close to 1 %, involving both genetic and environmental risk factors.
- Trial name
- SCHIZOCAN (NCT00798109)
- Testing
- Motivational therapy, Usual care
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cannabis Use Disorder
Trial of Tirzepatide for the Treatment of Cannabis Use Disorder
The purpose of this randomized, double-blind, placebo-controlled, multi-site clinical trial is to evaluate the safety and efficacy of tirzepatide in a sample of 100 patients diagnosed with moderate or severe CUD by DSM-5 criteria.
- Trial name
- NCT07468552
- Testing
- Tirzepatide
- Volunteers
- 100 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Drinking, Smoking
An Effectiveness Trial of Project ALERT
The purpose of this study is to replicate a longitudinal evaluation of Project ALERT, a substance abuse prevention program that targets middle school students.
- Conditions
- Alcohol Drinking, Smoking, Marijuana Smoking
- Trial name
- NCT00650585
- Testing
- Project ALERT
- Where
- United States
- Volunteers
- 8,338 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Postoperative Pain
Cannabis in Postoperative Pain Management
Postoperative pain management is critical for surgical recovery, affecting patient outcomes, hospitalization duration, and quality of life.
- Trial name
- Cannabis (NCT06903624)
- Volunteers
- 70,000 people
- Sponsor
- Assuta Medical Center
Cannabis, Pregnancy
Duration of Marijuana Concentration in Breast Milk- A Pilot Study
Legalization of marijuana in Colorado for both medicinal and recreational purposes has led to a perception of its safety, which has not been well studied in pregnant or lactating women.
- Conditions
- Cannabis, Pregnancy, Breast Feeding
- Trial name
- NCT02635568
- Testing
- Cannabis Use
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver