Clinical trials: Cannabis Abuse
Intensive Care Unit Syndrome, Drug Abuse
Addiction in Intensive Cardiac Care Units
Background: Illicit drug use is a growing issue in Europe and leading cause of acute cardiac events in patients admitted to intensive cardiac care units.
- Conditions
- Intensive Care Unit Syndrome, Drug Abuse, Substance-Related Disorders, Cardiovascular Events
- Trial name
- ADDICT-CCU (NCT05063097)
- Testing
- urine test, Fagerström questionnaire, Exhaled carbon monoxide (CO) measurement
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy, Healthy Volunteer
NTI164 Human PK Study
This study is looking at how a new cannabis compound with extremely low THC (0.08%), NTI164, is metabolised in the body and how it is excreted in urine over time (up to 28 days) in healthy adult volunteers.
- Trial name
- NCT06713447
- Testing
- NTI164
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fenix Innovation Group
Marijuana Dependence
Hormones and Reduction in Co-users of Marijuana and Nicotine
The purpose of this study is to examine the role of progesterone (a naturally occurring hormone found in both men and women) on reducing marijuana use.
- Trial name
- NCT02579421
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cannabis Use Disorder
Use of a Mobile Health Sensor in an Open Label Trial of Lorcaserin for the Treatment of Cannabis Use Disorder
This is a 10 week, open-label, prospective study, involving 10 volunteer participants with cannabis use disorder to test the feasibility and safety of using lorcaserin in addition to the feasibility, likability, and utility of a…
- Trial name
- NCT02932215
- Testing
- lorcaserin, Fitbit Charge HR
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- New York State Psychiatric Institute
Marijuana Abuse, Mood Disorders
Effectiveness of Buspirone and Motivational Enhancement Therapy for the Treatment of Marijuana Dependence - 1
This study will assess the effectiveness of a combination of buspirone and motivational interviewing therapy in the treatment of marijuana dependence.
- Trial name
- NCT00149617
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Medical University of South Carolina
Cannabis, Memory
Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 4
This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users.
- Conditions
- Cannabis, Memory, Electroencephalography
- Trial name
- COBRA 4 (NCT07679581)
- Testing
- Cannabis (smoked flower)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- L. Cinnamon Bidwell
Lean Body Mass, Cannabis
The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
An intervention study on the effect of cannabidiol on lean body mass in cancer patients receiving chemotherapy, at the department of Clinical Oncology at Zealand University Hospital, Roskilde, Denmark.
- Conditions
- Lean Body Mass, Cannabis, Cancer, Nausea
- Trial name
- NCT04585841
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Copenhagen
Opioid-use Disorder, Acceptability of Health Care
Patients' Attitudes Toward and Experiences With Buprenorphine Treatment
This study will disseminate five surveys collecting individual's attitudes and experiences during buprenorphine treatment for Opioid Use Disorder during the COVID-19 pandemic.
- Conditions
- Opioid-use Disorder, Acceptability of Health Care, Opioid-Related Disorders
- Trial name
- NCT05121428
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Chronic Pain, Opioid Use
Improving Pain Disability With the Use of Oral Cannabinoids
The investigators are conducting a pilot (i.e. a small study) in order to find out the effectiveness and safety of medical cannabis in the management of chronic pain.
- Conditions
- Chronic Pain, Opioid Use, Cannabis
- Trial name
- NCT05351905
- Testing
- CBD oil ( MPL-001), CDB+THC oil (MPL-005)
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University Health Network, Toronto
Endometriosis, Pelvic Pain
Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND)
The objective of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabis extract in women with endometriosis who have already undergone hormonal…
- Trial name
- DREAMLAND (NCT05670353)
- Testing
- Cannabis Derivatives, Hormonal Contraceptive Agents
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Solid Tumor, Adult
Cannabis Use in Cancer Patients
The goal of this study is to determine the feasibility of a human observational study of orally administered cannabis use among cancer patients.
- Trial name
- NCT03617692
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Colorado, Denver
Marijuana Abuse
Effects of Stress and Drug-cue Exposure (SCM)
The purpose of the proposed study to examine the links among stress, craving for marijuana, and marijuana reminders, or "cues". In this study, an agent called yohimbine will be used to produce stress-like responses.
- Trial name
- NCT03154567
- Testing
- Yohimbine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wayne State University
Alcohol Use Disorder
CBD for the Treatment of Alcohol Use Disorder
This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of full spectrum cannabidiol (CBD) and broad spectrum CBD, compared to a placebo control (PC), to reduce drinking in participants…
- Trial name
- NCT04873453
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Colorado, Denver
Cannabis Use, Drug Abuse
Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis
Background: Little research has been done on how different components of cannabis (marijuana) appear in oral fluid (i.e., saliva) after smoking.
- Trial name
- NCT01071616
- Testing
- Cannabis Cigarette
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol, Cannabis
A Hybrid Type 1 Randomized Controlled Trial of an Online and Text-Messaging Intervention to Prevent Alcohol and Cannabis Initiation, Escalation, and Consequences Among First-Year College Students
Building on promising pilot findings, this study will employ a Hybrid Type 1 Effectiveness-Implementation RCT to evaluate the effectiveness of a novel intervention for first-year college students who abstain from or use alcohol…
- Trial name
- NCT07905846
- Testing
- Online and Text Message Intervention
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Cannabis Dependence
Achieving Cannabis Cessation-Evaluating N-Acetylcysteine Treatment
The primary objective of this study is to evaluate the impact of N-acetylcysteine (NAC) 1200 mg versus matched placebo (PBO) twice daily, added to contingency management (CM), on cannabis use among treatment-seeking…
- Trial name
- ACCENT (NCT01675661)
- Testing
- N-Acetylcysteine
- Where
- 6 sites in United States
- Volunteers
- 302 people
- Sponsor
- Medical University of South Carolina
Drug Abuse, Intoxication by Drug
Evaluation of Smoked THC and CBD in Men and Women
The purpose of this study is to determine the pharmacokinetics and pharmacodynamics of inhaled cannabis with varying amounts of delta-9-tetrahydrocannabinol (THC), and cannabidiol (CBD) and to evaluate detection of recently…
- Conditions
- Drug Abuse, Intoxication by Drug, Impairment
- Trial name
- S-TACOFS (NCT05037487)
- Testing
- 20 mg CBD Cannabis, 20 mg CBD + 20 mg THC Cannabis, 20 mg THC Cannabis
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Opioid Use Disorder
Cannabis and Opioid Use Disorder
This study plans to enroll participants with opioid use disorder who are not currently seeking treatment to assess the effects of cannabis on opioid withdrawal and other related outcomes.
- Trial name
- NCT05729932
- Testing
- Inhaled vaporized cannabis, Intransal opioid
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Shanna Babalonis, PhD
Cannabis Use
Assessment of Cannabis Craving in Schizophrenia Using Virtual Reality
Background: Individuals with schizophrenia or schizoaffective disorders have a high prevalence of cannabis use. Understanding some of the environmental factors that maintain cannabis use, such as socially triggered cravings, is a…
- Trial name
- NCT01212081
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cancer
Cannabis Use and Outcomes in Black and White Patients With Cancer
The goal of the observational study is to learn how black and white patients with solid tumor cancer use cannabis, opioids and tobacco.
- Trial name
- C4C (NCT06037681)
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- State University of New York at Buffalo