Clinical trials: Cannabis Abuse
Opioid Use, Pain
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain…
- Conditions
- Opioid Use, Pain, Marijuana Use
- Trial name
- NCT04827992
- Testing
- Cannabis, Prescription Opioid Taper Support (POTS)
- Where
- 3 sites in United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Crohn's Disease, Ulcerative Colitis
Cannabidiol for Inflammatory Bowel Disease
There are many anecdotal reports about improvement of Inflammatory bowel diseases (IBD) with cannabis smoking. The most effective anti inflammatory compound known today is cannabidiol.
- Trial name
- NCT01037322
- Testing
- cannabidiol
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Meir Medical Center
Drug Resistant Epilepsy
CANnabinoids for Drug Resistant Epilepsy (DRE) in Adults and Children
Epilepsy is a neurological disorder affecting more than 50 million people globally, including more than 260,000 Canadians. Cannabidiol (CBD) reduces seizure frequency and improves quality of life for adults and children with Drug…
- Trial name
- CAN-DRE (NCT07023744)
- Testing
- CBD Isolate, CBD CHE
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
Marijuana Dependence
Effectiveness Study of Dronabinol and BRENDA for the Treatment of Cannabis Withdrawal
This treatment study is targeted specifically for those who want to stop using marijuana. We want to find out if patients who are dependent on marijuana and want to stop using are helped by a combination of the drug dronabinol…
- Trial name
- NCT00480441
- Testing
- Dronabinol, BRENDA therapy
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Solid Tumor, Adult
Cannabis Use in Cancer Patients
The goal of this study is to determine the feasibility of a human observational study of orally administered cannabis use among cancer patients.
- Trial name
- NCT03617692
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Colorado, Denver
Healthy Volunteers
Vaporization as a Smokeless Cannabis Delivery System
A study to evaluate the use of a vaporization system as a smokeless delivery system for inhaled marijuana.
- Trial name
- NCT00241592
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Center for Medicinal Cannabis Research
Driving Impaired, Alcohol Intoxication
Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
The overarching aim of this study is to examine the impact of acute cannabis and alcohol administration on driving performance, as well as identify methods for detecting driving under the influence of these substances.
- Conditions
- Driving Impaired, Alcohol Intoxication, Driving Under the Influence, Cannabis Intoxication
- Trial name
- NCT05273658
- Testing
- Cannabis, Alcohol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Suicide, Alcohol Abuse
Alcohol, Suicide and HIV Prevention for Teens in Mental Health Treatment
This study examines whether an integrated alcohol/substance abuse, suicide, and HIV prevention protocol is associated with lower onset and frequency of alcohol and other drug use, suicidal behavior, and high risk sexual behavior…
- Conditions
- Suicide, Alcohol Abuse, Drug Abuse, HIV
- Trial name
- NCT02228044
- Testing
- Prevention program
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- George Mason University
Substance-related Disorders, Depression
Primary Care iSBIRT to Reduce Serious Teen Health Risks
The goal of the project is to develop and test an internet/intranet-based Screening, Brief Intervention, and Referral to Treatment (iSBIRT) system for adolescents that targets a broad range of serious health-risks and problem…
- Conditions
- Substance-related Disorders, Depression, High-risk Sex
- Trial name
- NCT00891631
- Testing
- iSBIRT, iSBIRT/TE
- Where
- United States
- Sponsor
- Boston Children's Hospital
Cannabis Use, Tobacco Use
Effect of Cannabis on Cigarette Use Behavior
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of cigarettes.
- Conditions
- Cannabis Use, Tobacco Use, Cigarette Smoking
- Trial name
- NCT06609083
- Testing
- THC 30mg, THC 5mg, THC 0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Schizophrenia
Impact of Cannabis Consumption on Psychotic Symptoms and Reality Monitoring in Patients With Schizophrenia: a Real-life Study
This study aims to examine the dual effects of cannabis consumption on both positive and negative symptoms of schizophrenia, across laboratory and real-world contexts.
- Trial name
- F_r_IEND-3 (NCT07309159)
- Testing
- Ecological Momentary Assessment (EMA) and Reality Monitoring tasks
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Positron Emission Tomography
Brain Nicotine Receptor Density in Veteran Smokers
Cigarette smoking is more prevalent among Veterans (27%) than the general U.S. population (21%). Smoking is common among people who use marijuana or caffeine heavily, and the use of menthol cigarettes is becoming increasingly…
- Trial name
- BNRDVS (NCT01721473)
- Testing
- positron emission tomography scan
- Where
- 2 sites in United States
- Volunteers
- 184 people
- Sponsor
- VA Office of Research and Development
Amyotrophic Lateral Sclerosis, Cannabis
EMERALD TRIAL Open Label Extension Study
EMERALD OLE trial is an open-label extension of the EMERALD trial. Long term tolerability and safety of the MediCabilis CBD oil has not been extensively studied.
- Conditions
- Amyotrophic Lateral Sclerosis, Cannabis, CBD, Motor Neuron Disease
- Trial name
- EMERALD-OLE (NCT04997954)
- Testing
- MediCabilis CBD oil
- Where
- Australia
- Volunteers
- 7 people
- Sponsor
- Gold Coast Hospital and Health Service
Premature Atrial Contractions, Premature Ventricular Contractions
The MARY-JANE Cannabis and Heart Rhythm Trial
Despite recreational cannabis now being legal in 23 states, where more than 100 million Americans reside, studies on the actual health effects are limited.
- Trial name
- NCT06021613
- Testing
- Randomized instructions
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Food Effect Study of VER-01 in Healthy Volunteers
Evaluation of pharmacokinetics, tolerability and safety of VER-01 depending on the intake a high-fat meal in healthy volunteers
- Trial name
- NCT04930796
- Testing
- VER-01
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Vertanical GmbH
Type 2 Diabetes, Obesity
Exploring the Anti-inflammatory Properties of Cannabis and Their Relevance to Insulin Sensitivity
This study tests the effects of cannabinoid levels in blood on inflammation and insulin sensitivity both acutely and chronically in individuals across the weight spectrum.
- Conditions
- Type 2 Diabetes, Obesity, Cannabis Use, Insulin Sensitivity
- Trial name
- SONIC (NCT04114903)
- Testing
- Study A: Single use of cannabis flower product, Study B: Ad libitum cannabis use for four weeks or no cannabis use
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of Colorado, Boulder
Cannabis Dependence
Gabapentin Treatment of Cannabis Dependence
This is a study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.
- Trial name
- NCT00395044
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Scripps Research Institute
Cannabis Use, Tobacco Use
Effect of Cannabis on E-Cigarette Use Behavior
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of electronic cigarettes.
- Conditions
- Cannabis Use, Tobacco Use, Electronic Cigarette Use
- Trial name
- NCT06609109
- Testing
- THC High Dose, THC Low Dose, THC 0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cannabis Use Disorder
Teen Marijuana Check-Up
This study will test a behavioral intervention tailored for adolescents who smoke marijuana and have concerns about their use. The study's purpose is to determine whether this intervention (two-sessions of motivational…
- Trial name
- NCT01109563
- Testing
- Marijuana Check-Ins
- Volunteers
- 252 people
- Sponsor
- Denise Walker
Recreational Cannabis Use
Emotional Brain Processes in Recreational Cannabis Users
This fMRI study investigates neural correlates of emotion regulation, emotion processing and craving in recreational cannabis users.
- Trial name
- NCT02801214
- Testing
- fMRI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China