Clinical trials: Cannabis Use Disorder
Cannabis Use Disorder, Tobacco Use Disorder
Clinical Trial Tobacco Marijuana
Approximately 50% of persons seeking treatment for cannabis-use disorders (CUDs) regularly smoke tobacco. Combining tobacco with cannabis has become a common method of smoking cannabis.
- Trial name
- RCTTM (NCT02277665)
- Testing
- CUD Treatment, Tobacco Treatment
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Schizophrenia, Dual Diagnosis
Cannabis, Schizophrenia and Reward: Self-Medication and Agonist Treatment?
In this translational research proposal, based on our formulation, we seek to confirm and expand upon data obtained in our pilot study suggesting that cannabis and the cannabinoid agonist dronabinol, given in low dose to patients…
- Conditions
- Schizophrenia, Dual Diagnosis, Psychotic Disorder, Cannabis Use Disorder
- Trial name
- NCT01964404
- Testing
- Marijuana, Dronabinol
- Where
- 2 sites in United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Opioid Use, Pain
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain…
- Conditions
- Opioid Use, Pain, Marijuana Use
- Trial name
- NCT04827992
- Testing
- Cannabis, Prescription Opioid Taper Support (POTS)
- Where
- 3 sites in United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Cannabis Use Disorder
Understanding Effects of Cannabis Use and Abstinence on Neural Glutamate Homeostasis
This study will be the first in vivo human multimodal neuroimaging study exploring the relationship between mGluR5 availability (PET), neural oscillations (EEG), and cognitive function in people with CUD.
- Trial name
- NCT05664763
- Testing
- [18F]FPEB with PET, Cannabis abstinence
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University