Clinical trials: Capsule Opacification
Refractive Errors, Cataract
Refractive Outcomes After Cataract Surgery in Eyes With Pseudoexfoliation Syndrome
To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes…
- Trial name
- NCT04783909
- Testing
- Phacoemulsification cataract surgery
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Cataract Surgery Deneyimi, Cataract Surgery
Katarak Surgery and Care
Although cataract surgery is an effective treatment method for improving visual function, it is important to evaluate the quality of life, daily living activities, independence level and psychosocial well-being of patients in the…
- Trial name
- NCT07807761
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cataract
A Safety and Efficacy Study of a Dexamethasone Drug Delivery System for Postoperative Inflammation and Pain After Cataract Surgery
This is a safety and efficacy study of a Dexamethasone Drug Delivery System for anterior segment inflammation and pain following cataract extraction with lens implantation.
- Trial name
- NCT01605942
- Testing
- Dexamethasone Drug Delivery System
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Allergan
Cataract
Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery
The purpose of this study is to compare the effectiveness of Nepafenac Ophthalmic Suspension, 0.1% eye drops to Acular LS eye drops, used before and after cataract surgery, for treating inflammation in the eye.
- Trial name
- NCT00333255
- Testing
- Nepafenac Ophthalmic Suspension, 0.1%
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Refractive Errors
Trifocal Diffractive Intraocular Lens After Cataract Extraction With Phacoemulsification
Multifocal IOLs that maintain distance focus and improve near vision have been developed to reduce spectacle dependence.Multifocal IOLs improve patient performance of near-vision tasks, such as reading crafts, hobbies, and social…
- Trial name
- NCT04465279
- Testing
- Trifocal diffractive intraocular lens
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Diabetic Macular Edema
The Effect of Intravitreal Ozurdex on DME After Cataract Surgery
The purpose of this study is to assess the efficacy and safety of OZURDEX (dexamethasone intravitreal implant) 0.7 mg administered immediately after phacoemulsification and intraocular lens implantation in type 1 or 2 diabetic…
- Trial name
- NCT01748487
- Testing
- dexamethasone intravitreal implant (OZURDEX)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Uveitis, Cataract
Outcome of Different IOLs in Patients With and Without Uveitis
Cataract, is a clouding of the lens in the eye gradually leading to reduction of the visual acuity. In most cases it can be managed with surgery, removing the own lens and replacing it with an artificial lens, intraocular lens…
- Conditions
- Uveitis, Cataract, Inflammation, Posterior Capsule Opacification
- Trial name
- NCT02975895
- Testing
- Hydrophobic IOL: Vivinex (HOYA), Hydrophilic IOL: INCISE (Bausch+Lomb)
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Vastra Gotaland Region
Macular Edema, Cataract
Preoperative Topic Diclofenac as a Prevention of Postoperative Macular Edema in Patients With Diabetic Retinopathy
Diabetes has many negative effects on patients' general health. Among many other consequences it speeds up the cataract formation and that is why diabetic patients need cataract surgery very often.
- Conditions
- Macular Edema, Cataract, Diabetic Retinopathy
- Trial name
- NCT01694212
- Testing
- Perioperative Diclofenac eye-drops administration
- Where
- Croatia
- Volunteers
- 55 people
- Sponsor
- Eye Clinic Medic Zuljan Jukic
Cataract
Anterior Capsule Polishing Effect on Effective Lens Position
The purpose of this study is to evaluate effects of anterior capsule polishing on effective lens position (ELP) and actual axial movement of the intraocular lens (IOL) by measuring anterior chamber depth (ACD) patients with…
- Trial name
- NCT01598428
- Testing
- anterior capsule polishing
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shandong University
Ocular Inflammation
Safety and Efficacy Study of rEV131 in the Treatment of Ocular Inflammation After Cataract Surgery
The purpose of this study is to evaluate the safety and effectiveness of three concentrations of rEV131, a new investigational anti-inflammatory agent, compared to placebo (an inactive substance) and an FDA approved…
- Trial name
- NCT00353964
- Testing
- rEV131, Prenisolone sodium phosphate 1.0%, rEV131 vehicle
- Where
- United States
- Sponsor
- Evolutec Group
Macular Oedema, Cataract Surgery
Comparing Efficacy of Bromfenac 0.09%, Nepafenac 0.3% and Diclofenac 0.1% in Patients After Cataract Surgery
The goal of this clinical trial is to learn which of the drugs bromfenac 0.09%, nepafenac 0.3% and diclofenac 0.1% has better efficacy in treatment and prevention of cystoid macular oedema after cataract surgery.
- Conditions
- Macular Oedema, Cataract Surgery, NSAID (Non-Steroidal Anti-Inflammatory Drug)
- Trial name
- BND (NCT07178639)
- Testing
- Bromfenac 0.09 % Ophthalmic Solution, Nepafenac 0.3% Oph Susp, diclofenac 0.1% ophthalmic susp.
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Nemocnice Kolín
Cataract Complicated, Cataract Complications Operations
Performance of Two Sclera Fixated Intraocular Lens Concepts
To evaluate and compare the post-operative outcome of two different sceral fixated IOL concepts, the Yamane method (ZA9003, J\&J, USA) and the Carlevale IOL (FIL-SSF, Soleko, Italy).
- Trial name
- Carlevale (NCT05779306)
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- Austria
- Volunteers
- 26 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Dry Eye
Evaluation of the Effectiveness of Three Tear Substitute Formulations in Postoperative Discomfort After Cataract Surgery
The primary objective of this study is the assessment of three tear substitute formulations in terms of postoperative discomfort following cataract extraction surgery by means of phacoemulsification and intraocular lens…
- Trial name
- DRY-CAT (NCT07581548)
- Testing
- Sodium Hyaluronate 0.15% and Dexpanthenol 2% drops (Hylopan max), Sodium Hyaluronate 0.15% and Trehalose 3% drops (Thealoz duo), Sodium Hyaluronate 0.2% and Amino acids drops (Helenvision ultra)
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- Democritus University of Thrace
Cataract
A Prospective Observational Case Series of a Four-ring-haptic Acrylic One-piece IOL
To describe biocompatibility, postoperative results and complications after implantation of the Corneal Quatrix Evolutive (Corneal, Croma, Austria) intraocular lens, a hydrophilic acrylic intraocular lens (IOL) with 4-haptic…
- Trial name
- Qu01 (NCT01244373)
- Where
- Austria
- Volunteers
- 9 people
- Sponsor
- General Hospital Linz
Posterior Capsule Opacification
Posterior Capsule Opacification (PCO) With Single Piece Hydrophobic Versus Hydrophillic Intraocular Lens (IOL)
The purpose of the study was to compare the postoperative PCO results of the single-piece hydrophobic Acrylic IOLs versus the newer generation single-piece hydrophilic Acrylic IOLs in patients undergoing bilateral cataract…
- Trial name
- NCT01125345
- Testing
- Phacoemulsification
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Macular Edema Following Cataract Surgery
Trientine Hydrochloride for the Prevention of Macular Edema After Cataract Surgery in Patients With Type 2 Diabetes Mellitus
The primary purpose of the protocol is to evaluate whether Trientine Hydrochloride, a copper chelator which is an agent that binds with and removes copper, will be effective in minimizing macular edema after cataract surgery in…
- Trial name
- NCT01295073
- Testing
- Trientine Hydrochloride, For Arm B there is no therapeutic intervention other than standard of care, which is cataract surgery.
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Cataract
Cataract Surgery Technique and Ocular Clarity
The goal of this study is to study the restoration of quality of vision, expressed as straylight, in the immediate period after cataract surgery with two different phacoemulsification technologies.
- Trial name
- NCT05489198
- Testing
- cataract surgery with Centurion phacoemulsification system, cataract surgery with Quatera 700 phacoemulsification system
- Volunteers
- 15 people
- Sponsor
- Amphia Hospital
Visual To Compare the Visual Outcome Between AcrySof™ IQ Vivity™ and TECNIS Synergy™ Intraocular Lens (Model ZFR00V )
A Comparative Study of Visual Outcome of Two Extended Depth of Focus Intraocular Lenses After Cataract Surgery
The investigators aim to compare the visual performance of the most recently introduced extended depth of focus intraocular lenses ; AcrySofTM IQ VivityTM and TECNIS SynergyTM ( an extended depth of focus IOL ) regarding the…
- Trial name
- NCT05647421
- Testing
- IOL implantation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cataract
Bilateral Monofocal Versus Monofocal-EDOF IOL Implantation: Quality of Vision Comparison
The goal of this clinical trial is to compare visual quality after cataract surgery between two groups: bilateral monofocal intraocular lenses (IOL) and monofocal and contralateral extended depth-of-focus (EDOF) IOL implantation.
- Trial name
- COMEDI (NCT06002399)
- Testing
- cataract surgery
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cataract
Evaluation of Safety and Performance of the EyenableTM Intraocular Lens for Cataract Treatment
Cataract is characterized by the loss of the normal transparency of the crystalline lens. It is a progressive, chronic disease that affect individuals over the age of 50. It is the leading cause of blindness around the world.
- Trial name
- NCT06223113
- Testing
- EyenableTM PA60AS1 IOL
- Volunteers
- 200 people
- Sponsor
- Xi'an Eyedeal Medical Technology Co., Ltd