Clinical trials: Carbohydrate Intolerance, open to volunteers
Irritable Bowel Syndrome, Sucrose Intolerance Due to Sucrase-Isomaltase Deficiency
Sucrase-isomaltase Deficiency as a Cause of Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a functional disorder causing troublesome symptoms and reduced quality of life. It affects 10-20% of the population, hence creates large costs for society.
- Conditions
- Irritable Bowel Syndrome, Sucrose Intolerance Due to Sucrase-Isomaltase Deficiency, Carbohydrate; Malabsorption, Sucrase Isomaltase Deficiency
- Trial name
- NCT05159115
- Testing
- Low-FODMAP diet, Starch- and Sucrose Reduced Diet (SSRD)
- Volunteers
- 80 people
- Sponsor
- Lovisenberg Diakonale Hospital
Pre Diabetic, Hyperglycaemia (Non Diabetic)
Diabetes Prevention by Group Intervention and CGM Use in Pre-diabetic Adults
This study is being done to find better ways to help people with prediabetes prevent or delay the development of type 2 diabetes.
- Trial name
- CGM (NCT07543068)
- Testing
- Combines group sessions and CGM-based behavioral feedback
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Sam Houston State University
Lactose Intolerance
Screening of Lactose Intolerance Among IBS Patients Diarrhea Dominant
This cross-sectional study aims to determine the prevalence of lactose intolerance among patients with chronic diarrhea, assess its correlation with age and gender, and evaluate common symptoms in affected patients.
- Trial name
- NCT06931379
- Volunteers
- 70 people
- Sponsor
- Assiut University
Lactose Intolerance, Lactose Intolerant
Milk for Diabetes Prevention
Individuals with lactase non-persistence (LNP; determined by a functional variant in the LCT gene [rs4988235, GG genotype]) are susceptible to lactose intolerance in adulthood due to deficiency of lactase, the enzyme which…
- Conditions
- Lactose Intolerance, Lactose Intolerant, Lactase Persistence, Pre-Diabetes
- Trial name
- NCT06513026
- Testing
- Lactose-Containing Milk, Lactose-Free Milk
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Albert Einstein College of Medicine
Milk Intolerance, Milk Hypersensitivity
Goat vs. Cow Milk Digestive Tolerance
The objective of this study is to assess to what extent goat's milk is better tolerated than cow's milk among individuals who report being intolerant to cow's milk, and, if so, to understand the underlying factors.
- Conditions
- Milk Intolerance, Milk Hypersensitivity, Cow Milk Protein Sensitivity
- Trial name
- DIGIGOAT (NCT07239856)
- Testing
- Cow milk, Goat Milk
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Type 2 Diabetes, Prediabetes
Sweet Sensing in Type 2 Diabetes
Diabetes is a global challenge and the number of people affected by diabetes is expected to rise to 5.5 million by 2030, of which 90% are type 2 diabetes (T2D).
- Trial name
- NCT06804187
- Where
- United Kingdom
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome, Lactose Intolerance
The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION)
Irritable bowel syndrome (IBS) is a functional gastrointestinal disease. There is no well-defined pharmacological treatment. This clinical trial is a prospective, double-blind, two-armed randomized controlled, single-center…
- Conditions
- Irritable Bowel Syndrome, Lactose Intolerance, Lactose Malabsorption
- Trial name
- LION (NCT05100719)
- Testing
- alverine-citrate + simethicone and lactase
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- University of Pecs
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Evaluating a Liquid Extract of Carob to Improve Blood Sugar in People With Prediabetes
This study evaluates whether a liquid carob extract can improve blood glucose levels in individuals with prediabetes. Participants are selected according to predefined health criteria and randomly assigned to two groups: one…
- Trial name
- GLIA (NCT07379931)
- Testing
- Carob extract, Control product
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis
Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease
This single-arm pilot study evaluates the effects of whole-body electrical muscle stimulation (WB-EMS) exercise on neuromuscular and physical function in adults with neuromuscular disease (NMD).
- Conditions
- Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis, Myasthenia Gravis, Lambert-eaton Myasthenic Syndrome
- Trial name
- NCT07478172
- Testing
- Whole-body Electrical Muscle Stimulation Exercise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri-Columbia
Lactose Intolerant, Lactose Malabsorption
Proper Dietary Management, Follow-up, and Lactase Enzyme Supplementation for Lactose Intolerance
Lactose intolerance (LI) is considered the clinical syndrome caused by lactose malabsorption (LM). It is possible to identify four causes of lactase deficiency defining four different types of LM: primary (genetic), secondary…
- Conditions
- Lactose Intolerant, Lactose Malabsorption, Lactose Intolerance
- Trial name
- NCT06773650
- Testing
- Completion of online survey
- Where
- Italy
- Volunteers
- 385 people
- Sponsor
- European Institute of Oncology
Exercise, Endurance Cycling Performance
Maple Syrup Carbohydrate Dose-Response on 20-km Cycling Time-Trial Performance
The goal of this clinical trial is to learn whether maple syrup can be used as a natural carbohydrate source to help trained male cyclists perform better during long-duration cycling.
- Conditions
- Exercise, Endurance Cycling Performance, Carbohydrate Intolerance, Sport Nutrition
- Trial name
- MAPLE-DR (NCT07389837)
- Testing
- Maple Syrup Beverages, Pre-Trial Meals, D₂O Fluid Absorption
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Eating Almonds Before a Meal to Control Blood Sugar
The goal of this study is to learn whether eating a small serving of almonds before meals can improve blood sugar control in adults who have early signs of problems with blood sugar regulation.
- Conditions
- Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Precision Medicine, Nutrition
- Trial name
- NUTS (NCT07603739)
- Testing
- Premeal almond ingestion
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes, Pre Diabetes
Efficacy of Viome's Precision Nutrition Program Towards Reducing HbA1c
This is a randomized, placebo-controlled trial that will test the efficacy of VPNP in reducing HbA1c. Participant recruitment will occur through direct-to-participant enrollment.
- Trial name
- NCT05465616
- Testing
- Viome's Precision Nutrition Program (VPNP)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Viome
Irritable Bowel Syndrome (IBS)
New Microbiota-endocrine Axis in Fructose Malabsorption-caused Visceral Hypersensitivity in Irritable Bowel Syndrome.
Irritable bowel syndrome (IBS) affects around 4% of the general population and remains the most common functional bowel disorder.
- Trial name
- ENDOLORII (NCT07337707)
- Testing
- urine intestinal permeability test or lactulose/mannitol test, Blood test, food diary
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen