Clinical trials: Carbon Dioxide Pressure
Prematurity, Respiratory Distress Syndrome
CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure
This study seeks to determine if standard continuous positive airway pressure, known as CPAP is as effective as a more complicated approach that generates intermittent increases in airway pressure applied to the nostrils via a…
- Conditions
- Prematurity, Respiratory Distress Syndrome, Apnea of Prematurity
- Trial name
- NICA (NCT03670732)
- Testing
- continuous positive airway pressure, nasal intermittent positive pressure ventilation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 6 of 7)
NOTE: This is the sixth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919163
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Neurogenic Orthostatic Hypotension, Autonomic Failure
CO2 Rebreathing in nOH: A Proof-of-Concept Pilot Study
Neurogenic orthostatic hypotension (nOH) is a chronic condition associated with increased cardiovascular risk and reduced quality of life.
- Trial name
- NCT05908760
- Testing
- CO2 ReHaler
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of Calgary
Postoperative Respiratory Complications
The Clinical Value of Applying TOF and TcPO2 to Guide Elderly Patients Extubation
Three hundred aged(age>65y) patients were randomized to Commom group(C group). Qualitative TOF monitoring (TOF group). Qualitative TOF and transcutaneous partial pressure of carbon dioxide monitoring(Unite group).
- Trial name
- NCT02327910
- Testing
- TOF unit TcPCO2 group, TOF group
- Volunteers
- 300 people
- Sponsor
- Beijing Municipal Science & Technology Commission
Laryngoscopy, Apnea
High Flow Oxygen in Patients Undergoing Suspension Laryngoscopy Under General Anesthesia
Patients undergoing suspension laryngoscopy under general anaesthesia have oxygen delivered to their lungs through different methods. Inserting a tube in the trachea is the best means for oxygen delivery.
- Conditions
- Laryngoscopy, Apnea, Anesthesia
- Trial name
- OxALa (NCT03472118)
- Testing
- Nasal High Flow Oxygen
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- CMC Ambroise Paré
Bispectral Index, Transcutaneous Carbon Dioxide
Compare the Side Effects and Difference Awake Level of Three TCI Propofol Formula in TVOR Patients
This study is to find the fewer side effects formula of anesthesia for TVOR patients, to compare the BIS level during emergence and to find the correlation between BIS and transcutaneous carbon dioxide concentration.
- Conditions
- Bispectral Index, Transcutaneous Carbon Dioxide, PONV, Blood Pressure
- Trial name
- NCT00760253
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Laparoscopic Surgery
Factors Affecting Abdominal Compliance During CO2 Insufflation in Laparoscopic Abdominal Surgery
The authors aimed to evaluate factors influencing abdominal compliance in laparoscopic abdominal surgery.
- Trial name
- NCT06396351
- Testing
- Laparoscopic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara University
COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
Correlation Between PaCO2 and Respiratory Effort in Patients With COVID-19 With Extracorporeal Membrane Oxygenation
Excessive respiratory effort may cause self-inflicted lung injury (SILI) and inspiratory muscle injuries , stimulate desynchronization between the patient and ventilator , and worsen the perfusion of extrapulmonary organs .
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication, Respiratory Effort-Related Arousal
- Trial name
- NCT05882474
- Testing
- PaCO2
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Peking Union Medical College Hospital
Magnetic Resonance Imaging, Cerebrovascular Circulation
Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort
Brain blood flow will be measured during a simulated postural change test and while breathing increased levels of carbon dioxide using magnetic resonance imaging.
- Trial name
- NCT06629090
- Testing
- MRI, Prazosin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 4 of 7)
NOTE: This is the fourth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919228
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Anesthesia
The Effect of Pressure Support Ventilation on Spontaneous Breathing in Anesthetized Subjects
The aim of this prospective study is to determine the effect of pressure support ventilation (PSV) on minute alveolar ventilation (MAV) and end-tidal carbon dioxide (ETCO2) in anesthetized spontaneously breathing subjects by…
- Trial name
- NCT02385305
- Testing
- Pressure support ventilation by anesthesia machine (Apollo, Dräger)
- Sponsor
- Massachusetts General Hospital
Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department
The purpose of this clinical trial is to determine the best initial non-invasive respiratory support (NIRS) strategy for adults who present to the emergency department with acute hypoxemic respiratory failure, a condition in…
- Trial name
- WINDSURFER (NCT07558265)
- Testing
- Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ohio State University
Hyperventilation, Traumatic Brain Injury
Treatment of Spontaneous Hyperventilation With Remifentanil in Traumatic Brain Injury Patients
Spontaneous hyperventilation is common in severe traumatic brain injury patients and correlates closely with poor outcomes. How to treat this pathological condition remain unsolved.
- Trial name
- NCT04974060
- Testing
- Remifentanil Injection
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Magnetic Resonance Imaging, Cerebrovascular Circulation
Brain Blood Vessel Responses to Changes in Blood Flow
Brain blood flow will be measured during a simulated postural change test and while breathing increased levels of carbon dioxide using magnetic resonance imaging.
- Trial name
- NCT06629077
- Testing
- MRI, Prazosin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neurogenic Orthostatic Hypotension
Controlled CO2 Inhalation in NOH
This study focuses on neurogenic orthostatic hypotension (nOH), which is a disorder characterized by an abnormal drop in blood pressure (BP) within 3-minutes of standing.
- Trial name
- CO2-nOH (NCT06751888)
- Testing
- Controlled CO2 delivery
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of Calgary
Transcutaneous Carbon Dioxide Partial Pressure Monitoring, Retroperitoneoscopic Urologic Surgery
PTCCO2 Monitoring During Retroperitoneoscopic Urologic Surgery
To investigate the accuracy and correlation of estimating arterial CO2 pressure（PaCO2） using a transcutaneous CO2 pressure（PTCCO2） monitor in patients undergoing retroperitoneoscopic renal or adrenal surgery.
- Trial name
- NCT03226041
- Testing
- transcutaneous monitor (TCM-4 monitor)
- Where
- China
- Volunteers
- 32 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Partial Pressure of Carbon Dioxide
Correlation Between Peripheral and Central Venous Blood Partial Pressure of Carbon Dioxide in Critical Ill Patients
Observational study to analyze correlation between partial pressure of carbon dioxide from blood obtained from peripheral and central veins
- Trial name
- NCT03269448
- Testing
- Peripheral venous blood sampling
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Ramathibodi Hospital
Healthy
Studying Physiological and Anatomical Cerebral Effects of Carbon Dioxide and Tilt
The purpose of this study is to study the effects of carbon dioxide combined with head down tilt on cerebral physiology and anatomy.
- Trial name
- SPACE-COT (NCT02493985)
- Testing
- 0.5% CO2, ambient air
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 1 of 7)
NOTE: This is the first of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882516
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Cerebral Blood Flow
Cerebral Blood Flow Using Transfontanelle Ultrasound
We planned to evaluate cerebral blood flow and its association with age, blood pressure, and end tidal carbon dioxide in small pediatric using transfontanelle ultrasound during general anesthesia.
- Trial name
- NCT04070339
- Testing
- transfontanelle ultrasound
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital