Clinical trials: Carcinoma Breast
Cognitive Impairment
Gene Expression, Meditative Movement, and Emotional Distress (GME)
Study Title: Gene Expression, Meditative Movement and Emotional Distress (GME) Background and Objectives: Breast cancer survivors (BCS) often report decrements in cognitive functioning.
- Trial name
- GME (NCT04213872)
- Testing
- Meditative Movement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Arizona State University
Breast Cancer Screening, Colon Cancer Screening
Evaluating the Shared Decision Making Process Scale in Cancer Screening Decisions
The purpose of this retrospective observational study is to evaluate the performance of the Shared Decision Making Process scale in a sample of patients who have received a decision aid about the decision to screen or not screen…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Prostate Cancer Screening
- Trial name
- NCT04601272
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Impact of Obesity on the Efficacy of Endocrine Therapy With Aromatase Inhibitors
To see the impact of obesity on the efficacy of adjuvant endocrine therapy with aromatase inhibitors in postmenopausal patients with early breast cancer in terms of: i) Locoregional recurrence ii) Distant metastases iii)…
- Trial name
- NCT01758146
- Testing
- Tamoxifen, Letrozole
- Where
- India
- Volunteers
- 412 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pancreatic Adenocarcinoma Metastatic, BRCA1 Mutation
SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells
The clinical trial is a phase 1, single-arm trial that will evaluate the safety of the investigational treatment on metastatic pancreatic cancer and metastatic breast cancer.
- Conditions
- Pancreatic Adenocarcinoma Metastatic, BRCA1 Mutation, BRCA2 Mutation, Pancreatic Acinar Cell Carcinoma
- Trial name
- SHARON (NCT04150042)
- Testing
- Melphalan, BCNU, Vitamin B12B
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- General Oncology, Inc.
Advanced or Metastatic Breast Cancer
A Study to Understand the Patients Confirmed to Have Advanced or Metastatic Breast Cancer and Receiving Palbociclib Treatment Using a Real-world Database
The purpose of this real-world study is to look at breast cancer patients receiving Palbociclib using a large real-world database collected under real-world practice.
- Trial name
- NCT06962969
- Testing
- Ibrance
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Pfizer
Breast Cancer
PEAK PlasmaBlade™ 4.0 Versus Traditional Electrosurgery in Lumpectomy
The purpose of this clinical study is to quantify the difference in thermal injury depth at the surgical margin in breast lumpectomy specimens excised with the PlasmaBlade; to subjectively assess histopathologic sample quality…
- Trial name
- PRECISE (NCT00960154)
- Testing
- PEAK PlasmaBlade, Traditional Electrosurgery with scalpel
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medtronic Surgical Technologies
Breast Cancer
A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms
Breast cancer is one of the most prevalent cancers with 207,090 new cases of breast cancer and 39,840 deaths in women predicted for 2010 in the United States.
- Trial name
- AIMSS (NCT02874222)
- Testing
- surveys completed by subject
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- United States Naval Medical Center, San Diego
Breast Cancer, Depression
E-Mindfulness Approaches for Living After Breast Cancer
NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs…
- Trial name
- HEAL-ABC (NCT06748222)
- Testing
- Mindfulness (MAPs) Live Online, Mindfulness (MAPs) Digital App, Meditation Only Control Group
- Where
- 383 sites in United States, Puerto Rico
- Volunteers
- 402 people
- Sponsor
- NRG Oncology
HER2-positive Advanced Breast Cancer
T-DM1 Combined With CDK4/6 Inhibitor Ribociclib
To explore the efficacy and safety of T-DM1 combined with CDK4/6 inhibitor Ribociclib in the treatment of HER2-positive advanced breast cancer.
- Trial name
- NCT06481956
- Testing
- Ribociclib Oral Tablet
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zheng Yabing
Breast Cancer
Contrast-enhanced Spectral Mammography (CESM) Early Quantitative Evaluation of Tumoral Response and Pathologic Complete Response Prediction for Localized Breast Cancer Treated by Neoadjuvant Chemotherapy
Some types of localised breast cancer, including stage II and III, HER2 positive (Human Epidermal Growth Factor Receptor) or triple negative cancers are treated with primary or neoadjuvant chemotherapy prior to surgical treatment…
- Trial name
- CERePred (NCT06299202)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Male Breast Cancer, Recurrent Breast Cancer
Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Hormone Therapy
This pilot clinical trial studies vorinostat in treating patients with stage IV breast cancer receiving hormone therapy. Vorinostat may help hormone therapy work better by making tumor cells more sensitive to the drug.
- Conditions
- Male Breast Cancer, Recurrent Breast Cancer, Stage IV Breast Cancer
- Trial name
- NCT01720602
- Testing
- vorinostat, anastrozole, letrozole
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Washington
Breast Cancer
Prehabilitation for Breast Cancer Surgery
Prehabilitation for women diagnosed with breast cancer is commonly not part of the clinical pathways as little time (usually a few days) is left between diagnosis and surgery.
- Trial name
- NCT05216302
- Testing
- Group-based Nordic Walking Exercise Program
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Raquel Sebio
Breast Cancer Female, Pain, Postoperative
Pectoral Nerve Block During Mastectomy
Impact of pectoral nerve block on postoperative pain and quality of recovery in patients undergoing breast cancer surgery: A prospective study
- Trial name
- PNB (NCT05699902)
- Testing
- PECs block during mastectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Use of Intraoperative Radiotherapy in Breast Cancer
The Utility of Intraoperative Radiotherapy in Breast Cancer (RIOMA) is an observational project to understand the use and outcomes of intraoperative radiotherapy in patients with breast cancer under conditions of clinical use…
- Trial name
- RIOMA (NCT07030231)
- Testing
- Intraoperative
- Where
- Spain
- Volunteers
- 3,000 people
- Sponsor
- Parc de Salut Mar
Advanced Solid Tumor, HR+/HER2- Breast Cancer
A Study of BPI-1178 in Patients With Advanced Solid Tumor and HR+/HER2- Breast Cancer
BPI-1178 is a novel, orally administered inhibitor of both cyclin-dependent kinase 4（CDK4）and CDK6 kinase activity. This Phase I study is a first-in-human (FIH) clinical trial designed to evaluate the safety, tolerability, and…
- Trial name
- NCT04282031
- Testing
- BPI-1178, Fulvestrant, Letrozole
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beta Pharma (Suzhou) Co., Ltd.
BRCA1 Gene Mutation, BRCA2 Gene Mutation
Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability
This phase II trial studies how well pembrolizumab works in treating participants with cancer that has spread to other places in the body, has come back or has spread to nearby tissues or lymph nodes.
- Conditions
- BRCA1 Gene Mutation, BRCA2 Gene Mutation, Locally Advanced Solid Neoplasm, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT03428802
- Testing
- Laboratory Biomarker Analysis, Pembrolizumab
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Rutgers, The State University of New Jersey
Breast Cancer, Gastric Cancer (GC)
The Exploration of Novel Radionuclide-labeled HER2-targeting Antibodies in the Diagnosis of HER2-positive Malignancies
The purpose of this study is to develop and clinically evaluate 89Zr-labeled HER2-targeted antibodies in diagnosis and screening of HER2-positive cancer patients.
- Conditions
- Breast Cancer, Gastric Cancer (GC), Urothelial Carcinoma (UC)
- Trial name
- NCT07023861
- Testing
- 18F-FDG, 89Zr-LNCab190, 89Zr-LNCab002
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Affiliated Hospital of Jiangnan University
Breast Cancer
NAC Sparing Mastectomy After Neo-adjuvant Chemotherapy
Nipple areolar-complex (NAC) sparing mastectomy, extending the concept of skin-sparing mastectomy, allows to leave the nipple-areola complex intact and to provide a better cosmetic result.
- Trial name
- NCT02471742
- Testing
- NAC-sparing mastectomy, conventional mastectomy
- Where
- Italy
- Volunteers
- 573 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Breast Cancer Surgery, Post Operative Pain
The Effects of Peri-Operative Pregabalin on Post-Operative Pain Following Breast Cancer Surgery With Axillary Node Dissection: A Pilot Study
Breast cancer is a devastating disease. Some women with breast cancer undergo surgery to remove the breast and lymph nodes in the axilla (armpit).
- Trial name
- NCT00852683
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Nova Scotia Health Authority
Breast Cancer
mHealth Usage Among Nigeria Women Diagnosed With Breast Cancer Receiving Chemotherapy
The research is studying the effect of a mHealth psychoeducational intervention on self-efficacy, coping and psychological distress of Nigerian women diagnosed with breast cancer receiving chemotherapy The study is a two-arm…
- Trial name
- NCT05489354
- Testing
- mHealth psychoeducational intervention
- Where
- 2 sites in Nigeria
- Volunteers
- 126 people
- Sponsor
- Chinese University of Hong Kong
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