Clinical trials: Carcinoma of Lung
Lung Cancer Screening
Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System in Nevada and Mississippi: State-Based Initiative Component
This clinical trial studies whether a Quality Implementation of Lung Cancer Screening (QUILS™) System state-based initiative (SBI) intervention works to improve the statewide capacity for implementing and sustaining lung cancer…
- Trial name
- NCT07682597
- Testing
- QUILS SBI Intervention
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- Timothy Mullett
Lung Cancer
The Prognostic and Predictive Value of the CA-125 Marker in Lung Cancer Monitoring
The tumor associated CA-125antigen for diagnosis and follow-up of ovarian cancer was well defined. Increased serum CA125 level may have many diagnoses other than ovarian cancer, including breast, colorectal and lung cancer.
- Trial name
- NCT02437760
- Testing
- serum and pleural effusion CA-125 level
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- E-DA Hospital
Lung Cancer
Carboplatin, Paclitaxel, and Radiation Therapy With or Without Thalidomide in Patients With Stage III Non-small Cell Lung Cancer
This randomized phase III trial is studying carboplatin, paclitaxel, radiation therapy, and thalidomide to see how well they work compared to carboplatin, paclitaxel, and radiation therapy alone in treating patients with newly…
- Trial name
- NCT00004859
- Testing
- carboplatin, paclitaxel, thalidomide
- Where
- 236 sites in United States, South Africa
- Volunteers
- 589 people
- Sponsor
- National Cancer Institute (NCI)
Lung Diseases, Cancer, Lung
Analysis of Lung Cancer Tissue With Spatial Frequency Domain Imaging
This study investigates if a new imaging device can detect different types of lung tissue using spatial frequency domain imaging (SFDI).
- Trial name
- ALCATS (NCT06549088)
- Testing
- Spatial Frequency Domain Imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Cancer
Curative Study of Chinese Traditional Medicine to Treat Lung Cancer
The purpose of this study is to observe the efficacy of chemotherapy combined with Chinese patent drugs for patients with advanced non-small-cell lung cancer, also to evaluate the adverse reaction and the reliability.
- Trial name
- TCM (NCT02777788)
- Testing
- JinFuKang, XingZaoRuanJian, pemetrexed,docetaxel,gemcitabine,paclitaxel or vinorelbine combined with carboplatin、cis-platinum or nedaplatin
- Volunteers
- 120 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Small Cell Lung Cancer ( SCLC ), Lambert Eaton Myasthenic Syndrome (LEMS)
A Study to Evaluate the Incidence of Clinically Suspicious Lambert-Eaton Myasthenic Syndrome (LEMS) in Subjects Diagnosed With Small Cell Lung Cancer (SCLC)
This is a multi-center observational study in subjects with a diagnosis of small cell lung cancer. Screening and/or medical record review for symptoms associated with Lambert Eaton Myasthenic Syndrome (LEMS) will be conducted.
- Trial name
- NCT07075627
- Where
- United States
- Sponsor
- Addario Lung Cancer Medical Institute
Carcinoma, Non-Small-Cell Lung
Afatinib (BIBW 2992) in Advanced Non-Small Cell Lung Cancer Patients With EGFR Mutation
Primary objective of the trial is to evaluate the safety of afatinib in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring EGFR (Epidermal growth factor receptor) mutation(s) and have never…
- Trial name
- NCT01953913
- Testing
- Afatinib
- Where
- 33 sites in China, Hong Kong and 3 more
- Volunteers
- 542 people
- Sponsor
- Boehringer Ingelheim
Stage IV Lung Cancer, Stage IV Gastrointestinal Cancer
Pilot Randomized Clinical Trial of Informational Support Versus Spiritual Care
The purpose of this study is to address the need for effective spiritual care support for patients with lung and gastrointestinal cancer.
- Trial name
- PRaCTIS (NCT07176559)
- Testing
- Spiritual Care, Informational Support
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- Indiana University
Lung Cancer, Non-Small Cell
An Open-label Study of GSK1120212 Compared With Docetaxel in Stage IV KRAS-mutant Non-small Cell Lung Cancer
This is a phase II, open-label, multicenter, randomized study to evaluate the efficacy and safety of GSK1120212 compared with docetaxel in the second line setting for subjects with locally advanced or metastatic (Stage IV)…
- Trial name
- NCT01362296
- Testing
- GSK1120212, docetaxel
- Where
- 60 sites in United States, France and 6 more
- Volunteers
- 134 people
- Sponsor
- GlaxoSmithKline
Non-small Cell Lung Cancer
Trial of Ombrabulin (AVE8062) in Combination With Taxane and Platinum in Patients With Non-small Cell Lung Cancer
Primary Objective: To demonstrate progression free survival (PFS) improvement for ombrabulin compared to placebo, in combination with taxane and platinum, as first line treatment for patients with metastatic non-small cell lung…
- Trial name
- DISRUPT (NCT01263886)
- Testing
- ombrabulin (AVE8062)
- Where
- 43 sites in United States, Australia and 11 more
- Volunteers
- 176 people
- Sponsor
- Sanofi
Non Small Cell Lung Cancer
To Predict Efficacy by Detecting Circulating Endothelial Cell Subsets and Blood Perfusion Parameters Changes in Vivo Tumor in Study of QL1101 and Avastin® in Patients With Non-squamous Non-small Cell Lung Cancer
To reveal changes of peripheral markers and blood perfusion parameters in vivo tumor in the study of QL1101 and Avastin® in patients with Non-squamous Non-small Cell Lung Cancer
- Trial name
- NCT03195569
- Testing
- QL1101, Avastin®, Paclitaxel
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Small Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Cancer (LCNEC)
A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
This is a first-in-human, Phase 1/2, open-label, dose escalation, dose expansion and combination study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of Peluntamig…
- Conditions
- Small Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Cancer (LCNEC), Neuroendocrine Prostate Cancer (NEPC), Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)
- Trial name
- NCT05652686
- Testing
- Peluntamig (PT217), Carboplatin + Etoposide, Paclitaxel.
- Where
- 15 sites in United States
- Volunteers
- 203 people
- Sponsor
- Phanes Therapeutics
Non-small Cell Lung Cancer Metastatic
Armatinib Alone or in Combination With SRT for Brain Metastases EGFR-mutated Non-small Cell Lung Cancer
Objective:Patients with asymptomatic or minimally symptomatic Stage IV EGFR-positive NSCLC with baseline intracranial metastases.
- Trial name
- NCT05800223
- Testing
- Almonertinib, SBRT
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Cancer Hospital, China
Non Small Cell Lung Cancer
Efficacy and Safety Analysis of First-Line ABCP Therapy in Advanced SMARCA4-Mutated NSCLC
SMARCA4 mutation is clinically known to be an independent poor prognostic factor. Both TCGA and the investigators institution's preliminary research indicate that the median overall survival (OS) of mutated patients is…
- Trial name
- NCT07093762
- Testing
- Atezolizumab+Bevacizumab+Carboplatin+Paclitaxel
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Fuzhou General Hospital
Neoplasms Malignant
Studying An Investigational Drug Crizotinib (PF-02341066) In Non Non-Small Cell Lung Cancer Tumors That Are Positive For Anaplastic Lymphoma Kinase (ALK)
This is a Phase 1 trial evaluating the safety and efficacy of crizotinib in patients with tumors except non-small cell lung cancer that are positive for ALK.
- Trial name
- NCT01121588
- Testing
- Crizotinib
- Where
- 21 sites in United States, China and 5 more
- Volunteers
- 44 people
- Sponsor
- Pfizer
Non Small Cell Lung Cancer
Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural Effusion
This study intends to investigate the efficacy and safety of medical thoracoscopic cryotherapy combined with standard first-line treatment of advanced non-small cell lung cancer with malignant pleural effusion through a…
- Trial name
- NCT05291403
- Testing
- Medical thoracoscopic cryotherapy combined with standard first-line therapy for advanced non-cell lung cancer, Sequential intrathoracic injection of cisplatin/erythromycin combined with standard first-line therapy for advanced non-cell lung cancer, Standard first-line therapy for advanced non-cell lung cancer without intrathoracic treatment
- Where
- China
- Volunteers
- 141 people
- Sponsor
- Qianfoshan Hospital
Lung Cancer Screening, Smoking Cessation
Gain-framed Messages and NRT for Lung Cancer Screening Patients
This research is a randomized smoking cessation trial conducted within and specifically personalized for lung cancer screening patients presenting to a lung screening clinic.
- Trial name
- NCT03069924
- Testing
- Gain-framed messaging, Unframed messaging materials
- Where
- 2 sites in United States
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Non-small Cell Lung Cancer
Gefitinib Versus Vinorelbine/Platinum as Adjuvant Treatment in Stage II-IIIA(N1-N2) NSCLC With EGFR Mutation
Activating somatic mutations of the tyrosine kinase domain of epidermal growth factor receptor (EGFR) have been characterized in a subset of patients with advanced NSCLC.The EGFR mutation rate was 30% in Chinese Non-small Cell…
- Trial name
- ADJUVANT (NCT01405079)
- Testing
- Gefitinib, Vinorelbine+Cisplatin
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Guangdong Association of Clinical Trials
Metastases, Neoplasm, Carcinoma, Non-small Cell Lung
A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors
Study I3G-MC-JGCB (JGCB) is a multicenter, nonrandomized, open-label, dose-escalation Phase 1b study of LY2584702 in combination with either erlotinib or everolimus.
- Conditions
- Metastases, Neoplasm, Carcinoma, Non-small Cell Lung, Renal Cell Carcinoma, Neuroendocrine Tumors
- Trial name
- NCT01115803
- Testing
- LY2584702, Erlotinib, Everolimus
- Where
- 3 sites in United States, France
- Volunteers
- 29 people
- Sponsor
- Eli Lilly and Company
Non-small Cell Lung Cancer
Endobronchial Ultrasound vs Mediastinoscopy in NSCLC
Proper staging of Lung cancer is of paramount concern when determining a treatment regime. Currently the assessment of surgical candidacy is performed with the staging process, mainly the mediastinoscopy.
- Trial name
- NCT00372203
- Testing
- Endobronchial Ultrasound Guided Transthoracic Needle Biopsy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.