Clinical trials: Carcinoma of Prostate (Disorder)
Prostate Cancer, Prostate Cancer Metastatic
Geriatric Assessment and Technology Evaluation in Prostate Cancer
By doing this study, doctors hope to learn more about factors that contribute to frailty (a condition where older adults feel weak, get tired easily, and struggle more with everyday activities) and serious side effects among men…
- Trial name
- NCT06215508
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Prostate Cancer
A Prospective Randomized Trial of Prostate Biopsy Protocols Comparing the Vienna Nomogram and a Standard 10-core Biopsy Scheme
In this study, the investigators aim to determine if the Vienna nomogram increases the detection rate of TRUS-guided prostate biopsies by conducting a prospective randomized study comparing the Vienna nomogram with a 10-core…
- Trial name
- NCT01752140
- Testing
- 10-core prostate biopsy protocol, Vienna nomogram prostate biopsy protocol
- Where
- Portugal
- Volunteers
- 463 people
- Sponsor
- Hospital de Santa Maria, Portugal
Prostate Cancer
Prospective Multicentre Cohort Study PROREPAIR-B (mCRPC)
PROREPAIR is a prospective multicenter observational cohort study of unselected patients with metastatic Castration Resistant Prostate Cancer (mCRPC) with unknown germline mutational status at study entry and who are candidates…
- Trial name
- NCT03075735
- Volunteers
- 408 people
- Sponsor
- Centro Nacional de Investigaciones Oncologicas CARLOS III
Prostatic Neoplasms
Abiraterone With Discontinuation of Gonadotropin-Releasing Hormone Analogues in Metastatic Prostate Cancer
The goal of this study is to find out if patients with prostate cancer being treated with the medications abiraterone and prednisone can discontinue hormone injections (examples include leuprolide, goserelin, triptorelin and…
- Trial name
- NCT03565835
- Testing
- Abiraterone Acetate, Prednisone
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Montefiore Medical Center
Cancer, Metastatic, Cancer
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and…
- Conditions
- Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver
- Trial name
- NCT03452774
- Testing
- Clinical Trial Matching
- Where
- 68 sites in United States, Puerto Rico
- Volunteers
- 50,000 people
- Sponsor
- Massive Bio, Inc.
Prostate Cancer, Adenocarcinoma
Dose Escalation Study Using Ultra-Hypofractionated, Image-Guided, Intensity-Modulated Radiotherapy in Prostate Cancer
The purpose of this study is to test the safety of a new type of IG-IMRT called "ultra-hypofractionated IG-IMRT" where a higher dose of radiation is given to the tumor during each treatment day.
- Trial name
- NCT00911118
- Testing
- Hypofractionated, image-guided, intensity-modulated external beam radiation
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer, Adenocarcinoma of the Prostate
BrUOG 337: Olaparib Prior to Radical Prostatectomy For Advanced Prostate Cancer Defects in DNA Repair Genes
This study will evaluate approximately 3 months of treatment with the drug olaparib in patients with prostate cancer. A capsule formulation of olaparib (tradename Lynparza™) is approved by the United States Food and Drug…
- Trial name
- 337 (NCT03432897)
- Testing
- Olaparib Pill, Prostatectomy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Brown University
Intraepithelial Prostatic Neoplasia, Prostatic Neoplasms
The Effects of Lycopene on High Risk Prostatic Tissue
The purpose of this research study is to compare the effects of a lycopene supplement made from tomatoes to a placebo (a capsule with no active ingredients) in men who have abnormal cells in the prostate, but have not yet had…
- Trial name
- NCT01443026
- Testing
- Lycopene 30mg
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Illinois Chicago
Prostate Cancer
Prostate Cancer - Patient Empowerment Program
Each year over 20,000 men are diagnosed with prostate cancer in Canada with the majority undergoing some form of treatment option.
- Trial name
- PC-PEP (NCT03660085)
- Testing
- PC-PEP
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Arthritis of Knee, Arthritis of Hip
Comparison of the Diagnosis Time of VET and SCL in Patients With Intraoperative Coagulopathy
The present study is a prospective, multi-center observational trial comparing the times taken to diagnose coagulopathies using point-of-care (POC) viscoelastic tests or standard central laboratory tests (SCL tests) in patients…
- Conditions
- Arthritis of Knee, Arthritis of Hip, Spine, Prostate Cancer
- Trial name
- NCT06637943
- Testing
- SCL tests, POC viscoelastic tests
- Where
- 4 sites in South Korea
- Volunteers
- 210 people
- Sponsor
- Konkuk University Medical Center
Prostate Cancer
A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer
The primary purpose of this study is to determine the pharmacokinetics (PK) and pharmacodynamics (PD) of Debio 4228.
- Trial name
- NCT06395753
- Testing
- Debio 4228
- Where
- 21 sites in United States, France and 1 more
- Volunteers
- 55 people
- Sponsor
- Debiopharm International SA
Prostate Neoplasm, Prostatectomy
Efficacy of Extracorporeal Biofeedback Device for Post-prostatectomy Incontinence
To evaluate the efficacy of postoperative pelvic floor muscle training using personalized extracorporeal biofeedback device among patients with post-prostatectomy incontinence
- Conditions
- Prostate Neoplasm, Prostatectomy, Surgical Procedures, Robotic, Urinary Incontinence
- Trial name
- NCT02485665
- Testing
- Extracorporeal biofeedback device (Any Kegel)
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer, Prostate Cancer Stage I
Randomized Trial of HIFU vs. Cryo for Prostate Cancer
HIFU has been FDA approved and is widely utilized across the United States and Europe for the treatment of prostate cancer. Despite this, HIFU has not been offered within SCPMG until now due to growing patient demand.
- Conditions
- Prostate Cancer, Prostate Cancer Stage I, Prostate Cancer Stage II, High Intensity Focused Ultrasound
- Trial name
- KPFT (NCT06929065)
- Testing
- HIFU vs Cryoablation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Prostate Cancer
Chemotherapy in Treating Patients Who Have Metastatic Prostate Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether mitoxantrone and prednisone are more effective with or without prinomastat in…
- Trial name
- NCT00003343
- Testing
- endocrine-modulating drug therapy, mitoxantrone hydrochloride, prednisone
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- Pfizer
Prostate Cancer
A Study of Telemedicine Shared Medical Appointments (SMAs) Versus Individual Telemedicine Visits for People With Prostate Cancer
The purpose of this study is to see if a telemedicine group doctor's appointment is a practical (feasible) and acceptable method for following people with prostate cancer being managed with active surveillance when compared with…
- Trial name
- NCT05416996
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
Stereotactic Body Radiotherapy (SBRT) With Concurrent Boost for Low- and Intermediate-Risk Prostate Cancer
The purpose of this study is to determine whether stereotactic body radiation therapy (SBRT) with simultaneous boost (higher radiation dose) to areas within the prostate with more prominent cancerous growth (intraprostatic…
- Trial name
- Prostate SBRT (NCT01409473)
- Testing
- Prostate SBRT with concurrent boost to intraprostatic lesion(s)
- Where
- 2 sites in United States
- Sponsor
- Rocky Mountain Cancer Centers
Prostate Cancer
18F Fluciclovine (FACBC) PET/CT in Patients With Rising PSA After Initial Prostate Cancer Treatment
This prospective study will enroll up to 330 men with PSA-persistent or PSA-recurrent prostate cancer after curative-intent primary therapy and negative or equivocal findings on standard-of-care imaging.
- Trial name
- LOCATE (NCT02680041)
- Testing
- 18F-fluciclovine PET CT
- Where
- 17 sites in United States
- Volunteers
- 221 people
- Sponsor
- Blue Earth Diagnostics
Prostate Cancer
Open-label Phase IV Clinical Trial to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastases
To assess the effects of i.v. zoledronic acid 4 mg with respect to safety and tolerability
- Trial name
- NCT00242554
- Testing
- Zoledronic acid
- Volunteers
- 150 people
- Sponsor
- Novartis Pharmaceuticals
Prostate Cancer
Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer
RATIONALE: Stereotactic body radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue.
- Trial name
- NCT00547339
- Testing
- stereotactic body radiation therapy (SBRT)- 45 Gy, stereotactic body radiation therapy (SBRT) - 47.5 Gy, stereotactic body radiation therapy (SBRT) - 50 Gy (Phase 1)
- Where
- 5 sites in United States
- Volunteers
- 94 people
- Sponsor
- University of Texas Southwestern Medical Center
Prostate Cancer
Study to Evaluate the Presence of Lower Urinary Tract Symptoms (LUTS) in Prostate Cancer Patients Scheduled to Receive Luteinizing Hormone Releasing Hormone (LHRH) Analogues
The intention of this study is to investigate how many patients with prostate cancer, planned to be treated with LHRH analogues without history of surgery or radiotherapy, are suffering from LUTS.
- Trial name
- ANALUTS (NCT02542501)
- Where
- 32 sites in Portugal, Spain
- Volunteers
- 470 people
- Sponsor
- Ipsen
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