Clinical trials: Carcinoma of Prostate (Disorder)
Prostate Cancer
Efficacy and Safety of Leuprolide Acetate 22.5 mg Depot in Treatment of Prostate Cancer
Some patients with prostate cancer benefit from androgen deprivation therapy which reduces levels of testosterone. Leuprolide is a synthetic Luteinizing hormone releasing hormone (LHRH) analogue which upon administration can…
- Trial name
- NCT01415960
- Testing
- Leuprolide acetate 22.5 mg depot, GP-Pharm SA
- Where
- 25 sites in United States
- Volunteers
- 163 people
- Sponsor
- GP-Pharm
Prostate Cancer
ARMOR1: Study of TOK-001 to Treat Castration Resistant Prostate Cancer
The purpose of this study is to determine whether TOK-001 is safe and shows biological effect in the treatment of castration resistant prostate cancer (CRPC).
- Trial name
- ARMOR1 (NCT00959959)
- Testing
- TOK-001
- Where
- 8 sites in United States
- Volunteers
- 49 people
- Sponsor
- LTN PHARMACEUTICALS, INC.
Prostate Cancer (Adenocarcinoma)
Effect of ADT and ARPI on Bone Loss of Patients with Prostate Cancer
This study aims to assess the impact of Androgen Deprivation Therapy (ADT) and Androgen Receptor Pathway Inhibitors (ARPI) on bone quality in patients with prostate cancer.
- Trial name
- NCT06838520
- Testing
- Bone health assessment
- Where
- 4 sites in China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Genitourinary Cancers
Observational Study of the Effectiveness of Funded Drugs for Genitourinary Tumors.
SOGUG-PRINCIS is a retrospective (regarding patient inclusion) and prospective follow-up, epidemiological, non-interventional, non-blinded, non-randomized, multicenter, national observational study with drugs.
- Trial name
- SOGUG-PRINCIS (NCT06724159)
- Testing
- darolutamide, Nivolumab monotherapy, enfortumab vedotin
- Where
- 84 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Spanish Oncology Genito-Urinary Group
Breast Carcinoma, Prostate Carcinoma
Humidified Forest Oils for Immune System Recovery in Stage I-III Breast or Prostate Cancer
This clinical trial studies the feasibility of simulating forest therapy using humidified wood or fragrant oils, in improving immune cells, like natural killer cells, number and activity, and their downstream proteins, perforin…
- Trial name
- NCT05012813
- Testing
- Aromatherapy with Essential Oils
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
Study In Urology Practices Looking At Impact Of OncotypeDX GPS Test On Men Choosing And Remaining On Active Surveillance
Genomic Health's OncotypeDX® Prostate Cancer Assay is a commercially available laboratory test that measures the activity of certain genes in prostate cancer.
- Trial name
- NCT03502213
- Volunteers
- 489 people
- Sponsor
- Genomic Health®, Inc.
Prostate Cancer, Erectile Dysfunction
A Bio-psychosocial Sexual Health Intervention for Prostate Cancer Survivors and Partners: a Feasibility Study
The burden of sexual dysfunction after prostate cancer surgery is responsible for the single greatest impact on patient/partner health-related quality of life; substantially more so than concern for cancer recurrence, or any…
- Conditions
- Prostate Cancer, Erectile Dysfunction, Sexual Dysfunction
- Trial name
- BSHR (NCT02640131)
- Testing
- Biomedical Component, Psychosocial Component, Attention Control
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University Health Network, Toronto
Metastatic Cancer, Prostate Cancer
Calcium-41 (41Ca) Chloride Aqueous Solution in Diagnosing Patients With Prostate Cancer and Bone Metastasis
RATIONALE: Diagnostic procedures, such as radionuclide imaging using calcium-41 (41Ca) chloride aqueous solution, may help predict progressive disease in patients with prostate cancer and bone metastasis.
- Trial name
- UCDCC#217 (NCT00918645)
- Testing
- 41 Ca
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of California, Davis
Locally Recurrent Prostate Cancer
Focal Salvage HDR Brachytherapy for Locally Recurrent Prostate Cancer in Patients Treated With Prior Radiotherapy
This purpose of this study is to evaluate the safety and effectiveness of a technique called focal high-dose-rate (HDR) brachytherapy as treatment for prostate cancer that has come back in the prostate after prior radiotherapy.
- Trial name
- F-Sharp (NCT03312972)
- Testing
- HDR Brachytherapy
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
Adenocarcinoma of the Prostate, Stage III Prostate Cancer
Stereotactic Body Radiation Therapy in Treating Patients With Localized High-Risk Prostate Cancer
This clinical trial studies stereotactic body radiation therapy in treating patients with high-risk prostate cancer that has not spread to nearby lymph nodes or to other parts of the body.
- Trial name
- NCT02296229
- Testing
- stereotactic body radiation therapy, quality-of-life assessment, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Tecemotide (L-BLP25) in Prostate Cancer
This study examines tecemotide (L-BLP25) in combination with standard treatment for prostate cancer.
- Trial name
- NCT01496131
- Testing
- Radiation therapy, Goserelin, Cyclophosphamide
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- EMD Serono
Prostate Cancer
Comparison of Prostate Cancer-related Quality of Life in Sexually Active Men With Favourable Intermediate-risk Localised Prostate Cancer Treated With Total Prostatectomy or Focal HIFU
The goal of this trial is to assess the impact of focal HIFU therapy on quality of life in patients with favourable intermediate-risk localised prostate cancer.
- Trial name
- QUALIFY (NCT06945172)
- Testing
- Total prostatectomy, Focal HIFU
- Where
- France
- Volunteers
- 102 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Infection
PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy
Approximately one million transrectal prostate biopsies are performed annually in the U.S., and the risk of post- biopsy infection is increasing due to greater antibiotic resistance of rectal flora.
- Trial name
- PREVENT (NCT04843566)
- Testing
- Transperineal MRI-guided prostate biopsy, Transrectal MRI-guided prostate biopsy, Antibiotic (prophylaxis)
- Where
- 10 sites in United States
- Volunteers
- 687 people
- Sponsor
- Weill Medical College of Cornell University
Prostate Cancer
Vaccine Therapy in Treating Patients With Recurrent Prostate Cancer
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: Phase II trial to study the effectiveness of vaccine therapy in treating patients who have recurrent prostate cancer.
- Trial name
- NCT00030602
- Testing
- PSA prostate cancer vaccine, incomplete Freund's adjuvant
- Sponsor
- University of Maryland, Baltimore
Prostate Cancer
Postoperative Prognosis Management Service Based mHealth for Prostate Cancer Patients
Recently, the use of mobile health is increasing for the purpose of managing prognosis such as recurrence, survival and quality of life by using a wearable smart band and a smartphone application.
- Trial name
- NCT05021952
- Testing
- mHealth App and wearable device
- Where
- South Korea
- Volunteers
- 324 people
- Sponsor
- Seoul St. Mary's Hospital
Cancer Of Prostate, Prostate Neoplasms
A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer
Background: Metastatic castration sensitive and castration resistant prostate cancer (mCSPC and mCRPC) are prostate cancers that have spread to other parts of the body.
- Trial name
- NCT04633252
- Testing
- PDS01ADC, Docetaxel, M7824
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- National Cancer Institute (NCI)
Prostatic Neoplasms, Psychological Distress
ComCancer: Use of Let's Discuss Health Website by Patients With Prostate Cancer Undergoing Radiation Oncology Treatment
In Canada, the prevalence of cancer is growing and contributes significantly to health costs. The prevention and treatment of cancer is a major concern of our health system.
- Conditions
- Prostatic Neoplasms, Psychological Distress, Physician-Patient Relations, Communication
- Trial name
- NCT05787145
- Testing
- Let's Discuss Health Group
- Where
- 3 sites in Canada
- Volunteers
- 300 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Prostate Cancer
Oral Colchicine in Men With Castrate Resistant Prostate Cancer
The purpose of this study is to determine the prostate specific antigen response to continuous low dose oral colchicine.
- Trial name
- NCT01481233
- Testing
- Colchicine
- Sponsor
- Milton S. Hershey Medical Center
Prostate Cancer
Carbon-11 Labeled Sarcosine in Prostate Cancer
Men with and without prostate cancer will have a PET/CT scan that measures the level of the amino acid sarcosine. PET is a scanning method that uses short lived radioactivity.
- Trial name
- NCT02462447
- Testing
- 11C-sarcosine, 11C-choline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Prostate Cancer
Study Investigating the Pharmacokinetics, Pharmacodynamics and Safety of FE200486
Population pharmacokinetic and pharmacodynamic data from Study FE200486 CS06 and FE200486 CS02 provided further knowledge of the optimal dose regimens for FE200486 (degarelix).
- Trial name
- NCT00117949
- Testing
- Degarelix
- Where
- 12 sites in United States
- Volunteers
- 82 people
- Sponsor
- Ferring Pharmaceuticals
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