Clinical trials: Cardiac Anaesthesia
Anesthesia, Closed Loop Anesthesia Delivery System (CLADS)
Effect of Yoga on Anesthesia Management
TITLE: EFFECT OF SHORT-TERM PRANAYAMA ON ANAESTHESIA MANAGEMENT IN PATIENTS UNDERGOING CARDIAC SURGERY Primary aim: To evaluate the effect of pre-operative short term pranayama yoga on stress-induced hemodynamic (HR, MAP) changes…
- Trial name
- yoga (NCT03127891)
- Testing
- pranayama yoga, control group
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Nociceptive Pain, Goal-directed Therapy
Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery
This study will investigate the potential of guiding remifentanil analgesia during cardiac and vascular surgery in moderate to high risk patients requiring general anesthesia.
- Conditions
- Nociceptive Pain, Goal-directed Therapy, Hemodynamic Instability, Nol-Index
- Trial name
- NCT04137991
- Testing
- Nol-Index guided analgesia, Standard Analgesia
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Nerve Block, Coronary Artery Bypass
Comparison of Erector Spinae Plane Block and Transversus Thoracic Muscle Plane Block in Coronary Artery Surgery
The main objective of this study is to evaluate postoperative pain intensity comparatively between erector spinae plane block and transversus thoracic muscle plane block in patients undergoing open coronary artery surgery.
- Conditions
- Nerve Block, Coronary Artery Bypass, Anesthesia and Analgesia
- Trial name
- NCT06709625
- Testing
- Transversus thoracis plane block, Erector spina plane block (ESP)
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara City Hospital Bilkent
Non Cardiac Surgery
Peri-Operative And Long-Term Cardioprotective Properties Of Sevoflurane In High Risk Patients Undergoing Non-Cardiac Surgery
Non-cardiac surgery is associated with significant cardiac morbidity and mortality. Volatile anesthetics have a cardioprotective effects which results in preservation of left ventricular function and lower troponin I levels.
- Trial name
- NCT00336401
- Testing
- Sevoflurane or Propofol
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Female, Male
SEx-specific Differences in Cardiac Surgery Patients (SECS).
The aim of this study is to evaluate the differences between females and males undergoing cardiac surgery. The investigators will look at perioperative factors such as adaption of body weight, previous medical history…
- Conditions
- Female, Male, Surgery, Cardiac
- Trial name
- SECS (NCT06554925)
- Testing
- Cardiac surgery
- Where
- Netherlands
- Volunteers
- 10,000 people
- Sponsor
- Jennifer Breel
Post Dural Puncture Headache
"Isometric Lower Limbs Exercises Affect on Cardiac Parameters and Headache in Patient After Spinal Anesthesia"
the Objectives of this clinical trial is : 1. Examine the effect of lower limbs isometric muscle exercises on cardiac parameters in patients after spinal anesthesia. 2.
- Trial name
- LILE-SPA (NCT07547150)
- Testing
- Lower Limb Isometric Exercise
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karbala University
Anesthesia
Comparison of TIVA by Closed Loop Anaesthesia Delivery System Versus Target Controlled Infusion Device
Total intravenous anaesthesia (TIVA) is now being adopted as a preferred technique for providing GA because of its various inherent advantages like reduced PONV incidence, improved quality of recovery post GA, anti-inflammatory…
- Trial name
- NCT04731480
- Testing
- Propofol
- Where
- 2 sites in India
- Volunteers
- 160 people
- Sponsor
- Sir Ganga Ram Hospital
Undergoing Open-Heart Surgery
Opioids Continue to Play a Primary Role in the Management of Perioperative Pain Due to Opioid-Free Anesthesia in Open Heart Surgery.
Due to their superior efficacy in analgesia, opioids continue to play a primary role in the control of intraoperative and postoperative pain.
- Trial name
- Opioid-Free (NCT06683911)
- Testing
- non Opioids, Opioid
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Ankara City Hospital Bilkent
Hemodynamic Instability
Effect of Remimazolam and Propofol on Hemodynamic Stability During Anesthesia Induction in OPCAB Patients
Remimazolam is a novel ultra-short-acting benzodiazepine. Several studies demonstrated that its efficacy as a sedative hypnotics for general anesthesia is non-inferior to propofol.
- Trial name
- NCT05423951
- Testing
- REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO], Propofol, Rocuronium
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Seoul National University Hospital
Heart; Dysfunction Postoperative, Cardiac Surgery, Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery
The aim of the study is to delineate and compare the changes in coupled mechanical properties of left ventricle and arterial vascular bed caused by two popular anesthetic protocols commonly used in cardiac surgery (intravenous…
- Trial name
- NCT01397331
- Testing
- Isoflurane, Propofol
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Sheba Medical Center
Anesthesia
The Efficacy and Safety of Remimazolam Besylate for Cardiac Anesthesia
The evidence on the practice of remimazolam besylate during cardiac anesthesia is scarce. This study investigates the efficacy and safety of remimazolam besylate general induction and maintenance during cardiac surgery.
- Trial name
- NCT06717945
- Testing
- remimazolam besylate, propofol
- Volunteers
- 320 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Anesthesia Time
Single Lumen Intubation and Heart-Lung Machine (HLM) Mode Ventilation
In this trial, we aimed to compare anesthetic outcomes of single lumen intubation with Heart-Lung Machine mode ventilation versus double lumen intubation study in endoscopic thoracic sympathetic blockade.
- Trial name
- NCT05791045
- Testing
- single vs double
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Biruni University
Coronary Artery Disease, Postoperative Complications
Anesthesia Management of Coronary Artery Bypass Surgery and Inflammatory Biomarkers
The goal of this observational study is to evaluate effect of total intravenous anesthesia or inhalation anesthesia on inflammatory biomarkers in coronary artery bypass surgery and their relationship with early postoperative…
- Conditions
- Coronary Artery Disease, Postoperative Complications, Anesthesia
- Trial name
- NCT06209437
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people
- Sponsor
- Ankara City Hospital Bilkent
Hemodynamics After Spinal Anesthesia
Premedication and Haemodynamics After Spinal Anesthesia
Blood pressure drop following spinal anesthesia is connected with sympathetic/parasympathetic activity which may be determinated by Heart Rate Variability (HRV) assessment.
- Trial name
- NCT01066247
- Testing
- Morphine hydrochloride; Midazolam, Midazolam
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Propofol, Dexmedetomidine
Impact of Two Different Types of Sedation on ICEB
The QT interval is a measure of the combination of cardiac depolarization and repolarization as it encompasses both the QRS complex and the J-T interval.
- Conditions
- Propofol, Dexmedetomidine, Electrophysiological Balance Index, QT Interval, Variation in
- Trial name
- NCT05757063
- Testing
- Sedation with propofol, sedation with dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Cardiac Congenital Defects
Volume Versus Pressure Ventilation on Lung Atelectasis
This prospective randomized comparative study, to assess post-operative lung atelectasis by comparing calculated lung score using ultrasound between pediatric patients intubated with LMA (laryngeal mask airway) under volume…
- Trial name
- NCT06076395
- Testing
- LMA (Laryngeal Mask Airway)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Knee Arthroscopy, Spinal Anaesthesia
Investigation of the Effects of Two Different Anaesthesia Methods Applied to Patients Scheduled for Arthroscopic Knee Surgery on the Heart
The study will include 80 patients aged 18-65 years who will undergo elective arthroscopic meniscal surgery. Patients with bleeding disorders, cardiac disease, liver and/or renal failure, arrhythmia and electrolyte imbalance…
- Conditions
- Knee Arthroscopy, Spinal Anaesthesia, Lumbar/Sciatic Block
- Trial name
- NCT07423754
- Testing
- Knee Arthroscopy, Spinal Anaesthesia, Peripheral Nerve Block, Arthroscopic Knee Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Delirium, Post-Op Complication
Impact of Anesthesia Technique on Post-operative Delirium After Transcatheter Aortic Valve Implantation
Aortic stenosis is a frequent valvulopathy in Europe and North America. It occurs mainly over 65 years (2-7% of the population over 65 years). Treatment of symptomatic stenosis is an indication of aortic valve replacement.
- Conditions
- Delirium, Post-Op Complication, Anesthesia, Aortic Valve Disease
- Trial name
- DELIRIUMTAVI (NCT03323619)
- Testing
- anesthesia type
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Postoperative Pain
Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery
Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a…
- Trial name
- NCT05743231
- Testing
- interpectoral area block + serratus anterior area block group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Lung Cancer, Surgery
CMR Right Ventricular Contractile Reserve Following Lung Resection
Feasibility study investigating CMR dobutamine stress testing before and after lung resection
- Conditions
- Lung Cancer, Surgery, Anesthesia
- Trial name
- NCT06465277
- Testing
- Dobutamine stress CMR, Cardiac biomarker sample
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust