Clinical trials: Cardiac Anaesthesia
Postoperative Complications
Colloid Infusion for Optimal Outcomes In Non-cardiac Surgery (COIN Trial)
Hypotension is associated with postoperative complications. Preoperative fluid infusion can effectively prevent post-induction hypotension of general anesthesia.
- Trial name
- COIN (NCT05728645)
- Testing
- Hydroxyethyl Starch 130/0.4 and Electrolyte injection of 5ml/kg, Multiple Electrolytes injection of 5 ml/kg
- Where
- China
- Volunteers
- 2,022 people
- Sponsor
- Xijing Hospital
Hemodynamic Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine.
In this trial the investigators want to examine if there is any difference in hemodynamic stability when giving equipotent prophylactic injections of ephedrine 0,1 mg/kg, phenylephrine 1 microg/kg, norepinephrine 0,1 microg/kg or…
- Conditions
- Hemodynamic Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- VH (NCT03864094)
- Testing
- Ephedrine, Phenylephrine, Norepinephrine
- Where
- Norway
- Volunteers
- 128 people
- Sponsor
- Helse Fonna
Ischemic Heart Disease, Cardiac Valve Disease
Passive Leg Raising Test to Predict Hypotension During Induction of Anesthesia in Patients Undergoing Cardiac Surgery
Hypotension frequently occurs during anesthesia induction. Preload decrease by anesthetics was often considered as one of main causes for this hypotension. However, the studies on this topic have been lacking.
- Trial name
- NCT01144546
- Testing
- passive leg raising (45 degree leg elevation for 1-2 min)
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Seoul National University Hospital
Surgery, Postoperative Delirium
Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis
Postoperative neurocognitive disorders (PND) are serious and common complications after surgery, especially in elderly patients.
- Conditions
- Surgery, Postoperative Delirium, Anesthesia, Silent Stroke
- Trial name
- NCT06545786
- Testing
- Intraoperative electroencephalography
- Where
- Russia
- Volunteers
- 265 people
- Sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
Myocardial Revascularization, Spinal Anesthesia
Spinal Anesthesia Associated With General Anesthesia in Coronary Artery Bypass
CONTEXT: In patients eligible for coronary artery bypass surgery, anesthesia should provide a number of conditions that exceed the limits of cardiovascular stability, myocardial protection and other organs.
- Conditions
- Myocardial Revascularization, Spinal Anesthesia, Postoperative Care, Fentanyl
- Trial name
- NCT02840006
- Testing
- General anesthesia only, General anesthesia and Spinal anesthesia
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Daniel Gioielli de Castilho
Opioid Use
Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Heart Surgery
This study aims to assess the impact of bilateral deep parasternal intercostal plane block on intraoperative opioid consumption in open heart surgery
- Trial name
- NCT05103787
- Testing
- deep parasternal intercostal plane block, control
- Where
- 2 sites in Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cardiac IED Implantation
Cardiac Implantable Electronic Device Implantation With and Without Pectoral Nerve Block
Implantation of cardiac implantable electronic devices are generally carried out using intermittent intravenous conscious sedation combined with local anaesthesia.
- Trial name
- NCT03061292
- Testing
- Pectoral Nerve Block, Without Pectoral Nerve Block
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Changi General Hospital
Coronary Artery Bypass, Anesthesia
Sustainable Anesthesia in Myocardial Revascularization Surgery.
Introduction: Greenhouse gases threaten the health and safety of humanity. The Declaration of Helsinki seeks to protect human health and emphasizes the urgency of implementing sustainable strategies.
- Conditions
- Coronary Artery Bypass, Anesthesia, Sustainability
- Trial name
- NCT07508865
- Testing
- Optimized recovery, Standard Anesthetic Practice
- Where
- Chile
- Volunteers
- 116 people
- Sponsor
- Universidad de La Frontera
Hip Fractures, Anesthesia
Validation of Nexfin Cardiac Output in Elderly Patients With Hip Fracture
Measurement of how much blood the heart pumps may be useful in guiding how much intravenous fluid to give patients during surgery.
- Trial name
- NCT01474824
- Where
- 2 sites in United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Nottingham
Cardiopulmonary Disease
SGA for TEE: Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease.
Increasingly, transesophageal echos (TEEs) are being done on high risk patients. A TEE is a short procedure done with deep sedation, but poses an increased risk of apnea/ hypoxemia in those with pulmonary disease.
- Trial name
- SGA-TEE (NCT04939220)
- Testing
- TEE with SGA, TEE with Deep Sedation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Pulmonary Ventilation
Comparison of Ventilation Tubes Among Anesthetized Pediatrics
To discover whether different types of ventilation breathing tube influence ventilation effect of children/ neonate, the investigators analysis tidal volume, end tidal carbon dioxide, compliance among children and neonate under…
- Trial name
- NCT03822689
- Testing
- Ventilator breathing tube F2220, Ventilator breathing tube F2216, Ventilator breathing tube F1520
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Post Operative Pain
The Efficacy of PSB and Recto-intercostal Block Combination on Postoperative Pain in Patients Undergoing Cardiac Surgery Via Sternotomy: Case Series
The aim of this study was to investigate the effectiveness of the combination of Superficial Parasternal Block and Recto-Intercostal Fascial Plane Block in patient groups undergoing cardiac surgery via sternotomy by evaluating…
- Trial name
- NCT06553560
- Testing
- Parasternal Block and Recto-İntercostal Fascial Plane Block
- Volunteers
- 10 people
- Sponsor
- Cumhuriyet University
Maternal Hypotension, Labor Epidural Analgesia
Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia
The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby.
- Conditions
- Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
- Trial name
- NCT07272018
- Testing
- Epidural Analgesia (Standard Clinical Care)
- Volunteers
- 480 people
- Sponsor
- The Chaim Sheba Medical Center
Diabetes
Effects of Remimazolam and Propofol on Anesthesia Induction
The patients with diabetes who underwent laparoscopic cholecystectomy in the general surgery department of the Second Hospital of Shanxi Medical University were selected.
- Trial name
- NCT06009055
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zheng Guo
Coronary Artery Disease, Anesthesia
Xenon in Off-pump Coronary Artery Bypass Graft Surgery
Purpose of this study is to test whether xenon application during off-pump-coronary artery bypass (OPCAB)-surgery is safe and feasible.
- Trial name
- NCT01757106
- Testing
- Xenon, sevoflurane
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven