Clinical trials: Cardiac Arrest, completed
Cardiac Arrest
Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be…
- Trial name
- NCT01806844
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Myocardial Infarction, Cardiac Arrest
Troponin-T for Detection of Perioperative Cardiovascular Events
We will conduct a prospective cohort study evaluating the incidence of and optimal risk estimation model for major perioperative cardiovascular events in consecutive patients undergoing noncardiac surgery at the 'Herlev…
- Trial name
- VISION-pilot (NCT00443989)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Arrest, Seizures
Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest
Non-convulsive seizures (NCS) following cardiac arrest are common and are associated with worse neurologic outcomes and increased mortality. More prolonged seizures (status epilepticus) are associated with worse outcomes.
- Trial name
- NCT02458820
- Testing
- DSA EEG
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiac Arrest
Non Invasive Neuromonitoring After Cardiac Arrest
Cardiac Arrest is among the leading causes of death, with survival still well under 50% and the majority of the survivors suffering from moderate to severe neurologic deficits. The human, social and economic costs are staggering.
- Trial name
- NINCA (NCT02575196)
- Testing
- Non-invasive cerebral flow monitoring
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiac Arrest, Cardiopulmonary Resuscitation
Compression Is Life In Cardiac Arrest - Human Study (CILICA-HS).
The management of out-of-hospital cardiac arrest is complex and multifactorial. With an incidence between 5 and 15 per 10,000 (46,000 patients per year in France) and a survival rate of only 5% to 15%, the room for improvement…
- Trial name
- CILICA-HS (NCT03817892)
- Testing
- Guidance of the External Chest Compression, Rhythm of a relay 4 minutes
- Where
- 11 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Caen
Heart Arrest
Adrenaline During Resuscitation From Pulseless Electrical Activity
This is a prospective observational study at St. Olavs hospital in Norway. Data are gathered from defibrillators that have been in use during resuscitation from cardiac arrest.
- Trial name
- NCT04149730
- Where
- 2 sites in United States, Norway
- Volunteers
- 280 people
- Sponsor
- St. Olavs Hospital
Cardiac Arrest (CA), Simulation Training
Comparing Foot and Hand CPR
The goal of this simulation study is to evaluate whether chest compression using the foot is comparable to chest compression using the hand during cardiopulmonary resuscitation in trained participants.
- Trial name
- NCT06719401
- Testing
- Foot Chest Compression, Hand Chest Compression
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Ventricular Tachycardia, Sudden Cardiac Death
Intravenous n-3 Fatty Acids and Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillator (ICD)-Pacemaker
The long-chain n-3 polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), appear to offer protection against sudden cardiac death and ventricular arrhythmias.
- Trial name
- NCT00534300
- Testing
- Omegaven, Isotonic saline
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Aalborg University Hospital
Out-of-Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
Left Ventricular Ejection Fraction in Cardiac Arrest Survivors Treated With Extracorporeal Cardiopulmonary Resuscitation
Extra-hospital cardiac arrest is a major public health problem, with approximately 46,000 cases per year. Nearly 71% of the patients for whom resuscitation was initiated did not present a return of spontaneous circulation on…
- Trial name
- FEVGECMO (NCT06046339)
- Testing
- Collection of data from the patient's medical file
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Arrest, Neurological Complication
Bedside Monitoring of Cerebral Energy State During the Peri-cardiac Arrest Period
In comatose patients resuscitated from out of hospital cardiac arrest (OHCA), neurological injuries remain the leading cause of death.
- Conditions
- Cardiac Arrest, Neurological Complication, Post-Cardiorespiratory Arrest Coma
- Trial name
- MICA (NCT03095742)
- Testing
- Low MAP, High MAP
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Heart Arrest, Out-Of-Hospital, CardioPulmonary Resuscitation
Ventilation in Cardiac Arrest Resuscitation Study
Out-of-hospital cardiac arrest (OHCA) is a major public health problem, with around 40,000 victims each year in France. Their survival rate remains dramatically low, at less than 10%.
- Conditions
- Heart Arrest, Out-Of-Hospital, CardioPulmonary Resuscitation, Basic Cardiac Life Support
- Trial name
- VECARS (NCT05992454)
- Testing
- EOLIFE
- Where
- France
- Volunteers
- 120 people
- Sponsor
- French Defence Health Service
Heart Arrest
Comparison of Efficiency Between I-gel Blind Intubation and I-gel Bronchoscopic Intubation During Resuscitation
The investigators will compare conventional intubation using Macintosh laryngoscope, blind endotracheal intubation using i-gel for conduit and bronchoscopic intubation using Ambu-aScope and i-gel.
- Trial name
- i-gel_br (NCT02411422)
- Testing
- Conventional endotracheal tube, Reinforced endotracheal tube
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Cardiopulmonary Resuscitation, Cardiac Arrest
Physical Workload Identify in Chest Compression Position Using Surface Electromyogram
The chest compression depth decreases over time after starting continuous chest compression due to the rescuers' fatigue. The investigators hypothesized that the frequency parameters from surface electromyogram from each muscle…
- Trial name
- NCT02088879
- Testing
- chest compression with kneeling position, chest compression with standing position
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Brain Death
Computed Tomography Angiography Accuracy in Brain Death Diagnosis
The purpose of this study is to assess the reliability of computed tomography angiography (CTA) to diagnose brain death, face of several conditions that make impossible to define such diagnosis using clinical criteria exclusively.
- Trial name
- NCT02045407
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- Sergio Brasil, MD MSc
Out-of-Hospital Cardiac Arrest
Arizona Prehospital CPR Quality Improvement Project
The quality of cardiopulmonary resuscitation (CPR) provided to patients with out-of-hospital cardiac arrest (OHCA) is often suboptimal.
- Trial name
- NCT01258244
- Testing
- Audiovisual Feedback
- Where
- 2 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Valleywise Health
Heart Failure, Arrhythmias, Cardiac
Heart Failure and Sudden Cardiac Death Japan Registry
The purpose of this observational registry is to collect clinical events and outcome data in 4 different study populations (cohorts), with a majority of Japanese subjects, that are at risk of sudden cardiac death (SCD) and heart…
- Conditions
- Heart Failure, Arrhythmias, Cardiac, Sudden Cardiac Death
- Trial name
- HINODE (NCT03185832)
- Testing
- CRT-D, ICD, PM / CRT-P
- Where
- 34 sites in Japan
- Volunteers
- 354 people
- Sponsor
- Boston Scientific Corporation
Pediatric Cardiac Arrest (Simulated)
Examining the Effect of a Scripted Debriefing on Resuscitation Performance in Pediatrics
The investigative team's purpose for conducting this research is to improve effective and efficient translation and implementation of evidence based advanced life support practice to providers of care for children.
- Trial name
- EXPRESS (NCT01682629)
- Testing
- Debriefing Script, High Physical Realism Simulation
- Where
- Canada
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Arrhythmia, Cardiovascular Diseases
Multicenter Unsustained Tachycardia Trial (MUSTT)
To determine the value of electrophysiologic (EP)-guided antiarrhythmic therapy in coronary heart disease patients at increased risk for sudden death. The study included a controlled clinical trial and a registry.
- Conditions
- Arrhythmia, Cardiovascular Diseases, Coronary Disease, Death, Sudden, Cardiac
- Trial name
- NCT00000480
- Testing
- electrophysiology, anti-arrhythmia agents, defibrillators, implantable
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Brugada Syndrome, Cardiac Arrest
Feasibility of Improving Risk Stratification in Brugada Syndrome
Feasibility of Improving Risk Stratification in Brugada Syndrome (BrS), retrospective cohort study To study the reproducibility and specificity of V-CoS for activation heterogeneities predisposing to VT/VF in a larger series of…
- Conditions
- Brugada Syndrome, Cardiac Arrest, Athletes Heart, Atrial Fibrillation
- Trial name
- FIRST-BrS (NCT03992677)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Kidney Failure Chronic, Arrhythmias Cardiac
Effects of Marine n-3 Fatty Acids on Heart Rate Variability and Arrhythmias in Patients Receiving Chronic Dialysis
Background: End Stage Renal Disease (ESRD) patients have an extremely high mortality and the leading cause of death is cardiovascular disease which accounts for 50% of all deaths.
- Trial name
- NCT02147977
- Testing
- dietary supplement: n-3 PUFA, olive oil
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Aalborg University Hospital