Clinical trials: Cardiac Arrythmias
Atrial Fibrillation, Coronary Artery Disease
Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients
The objective of CAREBANK study is to establish definitive relationships with human cardiac samples and clinical phenotypes in patients undergoing cardiac procedures.
- Conditions
- Atrial Fibrillation, Coronary Artery Disease, Aortic Valve Stenosis, Aortic Valve Disease
- Trial name
- CAREBANK (NCT03444259)
- Testing
- Cardiac surgery
- Where
- Finland
- Volunteers
- 1,001 people
- Sponsor
- University of Turku
Arrhythmias
HIPACE High Frequency Low Energy Pacing to Terminate Fast Ventricular Arrythmias
People that have survived, or are at high risk of a lifethreatening ventricular arrhythmia are routinely offered a defibrillator (ICD).
- Trial name
- HIPACE (NCT02629445)
- Testing
- Cardiac Resynchronisation Defibrillator
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Cardiac Arrythmias
Sparsity-based Magnetic Resonance Imaging of Cardiac Arrhythmias
The primary purpose of this study is to improve the quality of Magnetic Resonance Imaging in patients with heart arrhythmia. Investigators will recruit 105 patients with arrhythmia and 30 control volunteers over 3 years and will…
- Trial name
- NCT02741180
- Testing
- 3D Imaging, Late Gadolinium Enhancement (LGE)
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Arrhythmia, Atrial Fibrillation
Esophageal 3D Mapping System for Cardiac Arrhythmias
The aim of the study is to develop and validate a novel esophageal mapping system to improve the diagnostics of cardiac arrhythmias.
- Conditions
- Arrhythmia, Atrial Fibrillation, Atrial Flutter, Atrial Tachycardia
- Trial name
- esoECG-3D (NCT03365440)
- Testing
- esoECG-3D catheter
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ventricular Arrythmias
Home-Monitoring in Implantable Cardioverter Defibrillator (ICD) Patients
The purpose of this study is to investigate the cost-effectiveness and effectiveness of remote-monitoring compared to standard care in patients with implantable cardioverter defibrillator.
- Trial name
- Monitor-ICD (NCT00787683)
- Testing
- Home-monitoring provided by LUMAX ICD device and CardioMessenger II
- Where
- 13 sites in Germany
- Volunteers
- 416 people
- Sponsor
- F. Mueller-Riemenschneider
Cardiomyopathy
Ventricular Arrhythmias in Uremic Cardiomyopathy
There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue.
- Trial name
- NCT01856400
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Congenital Heart Disease, Cardiomyopathies
Cardiac Rehabilitation for Young People
Heart problems are amongst the most common physical illnesses in children and young people (CYP). They can be present from birth or develop as CYP get older and are linked to increased physical and psychological difficulties…
- Conditions
- Congenital Heart Disease, Cardiomyopathies, Cardiac Arrythmias, Heart Failure
- Trial name
- CardioActive (NCT05968521)
- Testing
- Cardiac Rehabilitation (CR): Experimental, Treatment as usual: Control
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Greater Manchester Mental Health NHS Foundation Trust
Cardiac Arrythmias
Stellate Ganglion Block in Beating Heart Surgery
studies suggest that off-pump coronary artery bypass surgery is associated with improved outcomes when compared to on-pump coronary artery bypass.
- Trial name
- NCT03450226
- Testing
- stellate ganglion block
- Volunteers
- 40 people
- Sponsor
- Assiut University
Diabetes, Hypercholesterolaemia
The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans
Cardiovascular disease (CVD) is a major and persistent health disparity for African Americans. Linking GAINS is a randomized pilot and feasibility study designed to evaluate whether receiving genetic risk information early in a…
- Conditions
- Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus
- Trial name
- LINKING GAINS (NCT07833384)
- Testing
- Color Genomics Genetic Testing Panels
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS)
Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
Human induced pluripotent stem cells (hiPSCs) have driven a paradigm shift in the modeling of human disease; the ability to reprogram patient-specific cells holds the promise of an enhanced understanding of disease mechanisms and…
- Conditions
- Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS), Brugada Syndrome (BrS), Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
- Trial name
- NCT02413450
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Arrhythmia
Quality of Life Before and After Transcatheter Ablation in Children With Arrythmias
The goal of this clinical trial is to evaluate the improvement in the quality of life after the transcatheter ablation in children from 5 to 17 years old suffering for arrythmia who need a transcatheter ablation (according to…
- Trial name
- QUALICATRYTHM (NCT06808204)
- Testing
- Peds QL 4.0 (Pediatric Quality of Life), Ricci and Gagnon questionnaire, State and Trait Inventory
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Chagas Cardiomyopathy, Speckle Tracking Echocardiography
Cardiac Mechanics by Speckle Tracking as a Prognostic Predictor in Patients With Chagas Cardiomyopathy
This study aims to evaluate the prognostic value of myocardial mechanics parameters, including global longitudinal strain (GLS) and mechanical dispersion (MD), assessed through speckle tracking echocardiography, in patients with…
- Conditions
- Chagas Cardiomyopathy, Speckle Tracking Echocardiography, Arrythmias, Sudden Death
- Trial name
- ST-Chagas (NCT06806722)
- Where
- Brazil
- Volunteers
- 153 people
- Sponsor
- University of Sao Paulo
Sudden Cardiac Death, Left Ventricular Dysfunction
LifeVest Safety and Efficacy in Real Life Settings in France
This post-market study is a prospective observational study evaluating the efficacy and safety of the LifeVest in real-life settings.
- Conditions
- Sudden Cardiac Death, Left Ventricular Dysfunction, Cardiac Event, Cardiac Arrythmias
- Trial name
- WEARIT-FR (NCT03319160)
- Testing
- Wearable Cardioverter Defibrillator
- Where
- 2 sites in France
- Volunteers
- 1,164 people
- Sponsor
- Zoll Medical Corporation
Schizophrenia, Schizoaffective Disorder
Changes in Heart Rhythms Associated With Antipsychotic Drug Treatment
This study is being done to look at the electrical activity of the heart. This study will help decide whether taking recordings for a 24-hour period gives more useful information than recording it for a few seconds in a doctor's…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT00538122
- Testing
- 24 Holter Monitor Recording
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vanderbilt University
Ventricular Arrythmias
Efficacy of the ATP Switch Automatic Programming in Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy Defibrillator (CRT-D) Implanted Patients
Primary objective is to assess the efficacy of the new ATP Autoswitch function in simple, dual or triple chamber ICD.
- Trial name
- ASAP (NCT01169246)
- Where
- France
- Volunteers
- 1,254 people
- Sponsor
- MicroPort CRM
Atrial Fibrillation, Arrythmia
Comparison of Efficacy and Safety of Two Biphasic Defibrillators in Cardioversion of Atrial Fibrillation
Background: Biphasic truncated exponential (BTE) waveforms are standard for cardiac defibrillation and synchronized cardioversion up to date.
- Conditions
- Atrial Fibrillation, Arrythmia, Electric Countershock
- Trial name
- NCT04032678
- Testing
- Schiller Defigard Touch 7 - DGT7, Schiller Medical, France, LIFEPAK 15, Physio-Control Inc., Redmond, WA, USA
- Where
- Bulgaria
- Volunteers
- 75 people
- Sponsor
- University National Heart Hospital
Acute Coronary Syndrome, Diabetes Mellitus
Acute Coronary Syndrome in Diabetic Patients
This study aims to compare the clinical profile and outcomes of acute coronary syndrome patients with diabetes and without diabetes.
- Conditions
- Acute Coronary Syndrome, Diabetes Mellitus, Heart Failure, Acute Pulmonary Edema
- Trial name
- NCT03607201
- Testing
- No intervention
- Where
- Indonesia
- Volunteers
- 86 people
- Sponsor
- Tarumanagara University
Ventricular Arrythmia, Cardiogenic Shock
Recurrent Ventricular Arrythmias in ICU
Electrical storm (ES) is a life-threatening syndrome defined by the recurrence of ventricular arrythmias. ES is also represented by a wide spectrum of clinical situations ranging from recurrent monomorphic VT reduced by…
- Conditions
- Ventricular Arrythmia, Cardiogenic Shock, Electrical Storm
- Trial name
- ElectStorm (NCT07033065)
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Postoperative Cardiac Complication
Celiprolol Versus Ditiazem for the Prevention of Postoperative Cardiac Arrythmias in Thoracic Surgery
Cardiac arrythmias are the most common cardiac complications after thoracic surgery. They are made primarily of postoperative atrial fibrillation (POAF).
- Trial name
- CelDilPreCA (NCT03752931)
- Testing
- Celiprolol, Diltiazem
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Abderrahmane Mami Hospital
Heart Failure, Ventricular Arrythmias
Safety and Efficacy of Automatic Testing Feature in New ICDs and CRT-Ds
This study is a prospective, non-randomized, multi-center clinical trial that will assess the safety and effectiveness of investigational models of the Promote™ RF CRT-D and Current™ RF ICD devices.
- Trial name
- NCT00746356
- Testing
- Testing of the autocapture features of the device
- Where
- 5 sites in United States
- Volunteers
- 128 people
- Sponsor
- Abbott Medical Devices