Clinical trials: Cardiac Bypass Patients
Heart Attack, Cardioplegia Solution Adverse Reaction
Combined Use of a Novel Cardioplegic Formula With MPS® Versus Cardioplexol ® in Urgent Isolated CABG Using MiECC in Patients With Recent Acute Myocardial Infarction
The goal of this study is to compare the two cardioplegia solutions (blood cardioplegia by means of MPS ® vs. Cardioplexol ®) regarding perioperative outcome and with special attention to cardiac markers in patients with a recent…
- Conditions
- Heart Attack, Cardioplegia Solution Adverse Reaction, Coronary Artery Bypass Grafting (CABG)
- Trial name
- NCT04309994
- Testing
- Myocardial protection system (MPS), Cardioplexol
- Where
- Switzerland
- Volunteers
- 307 people
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Artery Disease
Prophylactic Administration of Levosimendan in Patients Undergoing Coronary Surgery
The present pilot study aims to investigate the effectiveness of the preoperative infusion of levosimendan in patients with impaired left ventricular function undergoing coronary artery bypass grafting.
- Trial name
- NCT01318460
- Testing
- Levosimendan infusion
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- AHEPA University Hospital
Coronary Artery Bypass
Short-Stay Intensive Care for Coronary Artery Bypass Patients
Objective: To evaluate the safety and cost-effectiveness of Short Stay Intensive Care (SSIC) treatment for low-risk coronary artery bypass patients Design: Randomized clinical equivalence trial Setting: University Hospital…
- Trial name
- NCT00707044
- Testing
- Control group (usual care), Short-Stay Intensive Care treatment (SSIC)
- Where
- Netherlands
- Volunteers
- 597 people
- Sponsor
- Maastricht University Medical Center
Postoperative Hypothermia in Patients With Cardiopulmonary Bypass
Incidence and Risk Factors of Postoperative Hypothermia in Cardiac Surgery
Background: Postoperative hypothermia may result in relevant complications such as adverse cardiovascular events, wound infection, and coagulopathy with consecutive blood loss.
- Trial name
- NCT02244034
- Testing
- hypothermia
- Where
- Thailand
- Volunteers
- 760 people
- Sponsor
- Mahidol University
Postoperative Pain, Coronary Artery Bypass Grafting (CABG) Surgery
Intertransverse Process Block for Postoperative Acute Pain After Coronary Bypass Surgery
This prospective, randomized controlled trial aims to evaluate the effect of bilateral intertransverse process block (ITPB) on acute postoperative pain in patients undergoing coronary artery bypass grafting (CABG) via median…
- Conditions
- Postoperative Pain, Coronary Artery Bypass Grafting (CABG) Surgery, Sternotomy
- Trial name
- NCT06908681
- Testing
- Bilateral Intertransverse Process Block (ITPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mustafa Aydemir
Coronary Artery Disease
Home-Based Versus Center-Based Cardiac Rehabilitation After CABG Surgery
This randomized controlled trial was designed to compare the efficacy of a 12-week home-based telerehabilitation (HBTCR) program against traditional center-based cardiac rehabilitation (CBCR) and usual care in patients who have…
- Trial name
- NCT07243444
- Testing
- Structured Exercise Program, Standard Health Education
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Hospital of Hebei Medical University
Coronary Artery Bypass
TELEsurveillance of Patients in PostopErative Bridge surgeryAge CoronairE
More than 20,000 patients benefit from coronary bypass surgery in France each year. Median discharge without complication is eight days postoperatively, whereas by day four after surgery, hospitalization is only necessary for…
- Trial name
- TELE-PEACE (NCT04236271)
- Testing
- connected objects
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Bypass Graft Surgery, Spine Surgery
Does Pre-operative Carbohydrate Loading Reduce Insulin Resistance and Improve Outcomes in Elective Surgical Patients?
The recent development of an oral carbohydrate drink for consumption prior to elective surgical procedures has been shown to improve insulin sensitivity.
- Trial name
- Preop (NCT00618592)
- Testing
- PreOp carbohydrate drink
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Patients Undergoing Cardiac Surgery, Patients With Coronary Artery Bypass Surgery With CEC
Ability of Pupillometry to Reduce Sufentanil Consumption in Planned Cardiac Surgery: Randomized, Controlled, Single-center Clinical Superiority Trial
The objective of general anesthesia is to obtain a loss of consciousness, stillness, and sufficient analgesia to allow surgery. Thus, general anesthesia has two components: hypnosis and analgesia.
- Trial name
- PUCCAR (NCT03864016)
- Testing
- Induction and maintenance of anesthesia, Adaptation of sufentanil doses according to the usual protocol, Adjustment of sufentanil doses according to pupillometry
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Metabolism Disorder
Conventional Fasting Versus Lipid/Carbohydrate Infusion for Coronary Bypass Patients
Comparative study between conventional fasting versus overnight infusion of lipid or carbohydrate on free fatty acids and insulin in obese patients undergoing elective first time on-pump coronary artery bypass grafting.
- Trial name
- NCT03033667
- Testing
- G group, group L, Group C
- Volunteers
- 63 people
- Sponsor
- Cairo University
Hemodynamics
Levosimendan Versus Milrinone in Off Pump CABG Surgery
To compare the efficacy of Levosimendan versus Milrinone in supporting hemodynamics during off-pump coronary artery bypass grafting surgery in patients with low ejection fraction.
- Trial name
- NCT03855579
- Testing
- Levosimendan, Milrinone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Coronary Artery Disease
Association Between Intraoperative Pulse Pressure Variation and Postoperative Lactate Clearance in Cardiac Surgery
This study aims to evaluate the relationship between intraoperative pulse pressure variation (PPV) and postoperative lactate clearance in adult patients undergoing elective cardiac surgery.
- Trial name
- NCT07871188
- Testing
- No Study-Specific Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Elzem SEN
Coronary Artery, Anxiety
The Effect of Diaphragmatic Breathing Exercise on Symptom Severity, Sleep Quality and Anxiety in CABG Patients.
Coronary artery bypass surgery (CABC) is a commonly performed surgical procedure for the treatment of blockages in the heart vessels. This surgical intervention aims to improve the blood circulation of the patients' heart muscle.
- Conditions
- Coronary Artery, Anxiety, Symptom, Sleep
- Trial name
- NCT06356896
- Testing
- diaphragmatic breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- KTO Karatay University
Videolaryngoscopy
Laryngoscopy and Coronary Artery Bypass Graft Surgery
In this prospective, randomized, controlled trial, the purpose is to compare Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope in terms of hemodynamic response…
- Trial name
- VL (NCT06349005)
- Testing
- Tracheal intubation using Storz VL, Tracheal intubation using Macintosh laryngoscopy, Tracheal intubation using MacGrath VL
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Acute Coronary Syndrome, Coronary Bypass Stenosis
Coronary CT Angio Evaluating Graft Patency in ACS Patients Treated With DAPT or Single ASA After CABG (CoCAP)
The purpose of this study is to compare the presence of graft patency in single aspirin vs dual anti platelet therapy (DAPT) treatment including ticagrelor in patients with acute coronary syndrome (ACS) treated with coronary…
- Trial name
- NCT04783701
- Where
- 6 sites in Norway, Sweden
- Volunteers
- 360 people
- Sponsor
- University Hospital, Linkoeping
Postoperative Complications
Cardiac Surgery and Postoperative Organ Dysfunction
The aim of the study is to identify the correlation between ischaemia reperfusion injury and postoperative multiorgan damage during cardiopulmonary cardiac surgery; and to investigate biomarkers that can predict postoperative…
- Trial name
- NCT05529212
- Testing
- ischemic reperfusion injury
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Cardiopulmonary Bypass Surgery
Efficacy of Pathogen Inactivation Strategies for Platelet Transfusion
This is a prospective randomized clinical trial designed to determine the hemostatic ability of pathogen reduced platelet, when compared to non-pathogen reduced platelets suspended in platelet additive solution.
- Trial name
- NCT06535360
- Testing
- Platelet transfusion
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Maryland, Baltimore
Acquired Bleeding Disorder, Cardiac Surgery Requiring Cardiopulmonary Bypass
Multi-national Study Investigating the Effect and Safety of rFXIII on Transfusion Needs in Patients Undergoing Heart Surgery
This trial is conducted in Canada, Asia, Europe and USA. The aim of this clinical trial is to investigate the effect and safety of rFXIII on transfusion needs in patients undergoing heart surgery.
- Trial name
- NCT00914589
- Testing
- catridecacog
- Where
- 32 sites in United States, Canada and 8 more
- Volunteers
- 479 people
- Sponsor
- Novo Nordisk A/S
Obesity, Morbid
ECG Triggered Dual Source CT for Non-invasive Pre-operative Cardiac Imaging in Morbid Obese Patients
Coronary arterial disease is a risk factor for bariatric surgery and might be a predictor for later major adverse coronary events.
- Trial name
- NCT02802579
- Testing
- standard protocol, enhanced protocol, enhanced obesity protocol
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Cantonal Hospital of St. Gallen
Coronary Artery Disease, Endotoxin-mediated Complications From Cardiopulmonary Bypass Surgery
Efficacy and Safety Study on bIAP
The study drug bIAP, or matching placebo, will be administered as a bolus of 1000 Units bIAP or matching placebo prior to anaesthesia (T = -15 minutes), directly followed by intravenous continuous infusion of about 5.6 units per…
- Trial name
- APPIRED (NCT01010724)
- Testing
- bIAP
- Where
- Netherlands
- Sponsor
- Catharina Ziekenhuis Eindhoven