Clinical trials: Cardiac Bypass Patients
Cardiac Output, High
Mean Systemic Filling Pressure and Heart Performance Predicting Fluid Responsiveness
Determining fluid responsiveness in critically ill patients by measuring mean systemic filling pressure on the intensive care unit.
- Trial name
- NCT02060942
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Obesity, Coronary Artery Disease
Impact of Body Weight on Outcomes of Patients Undergoing Coronary Artery Bypass Grafting
All consecutive patients who underwent isolated coronary artery bypass grafting (CABG) at our institution from 2014 to 2020 were included.
- Conditions
- Obesity, Coronary Artery Disease, Angina Pectoris, Coronary; Ischemic
- Trial name
- NCT06614023
- Testing
- coronary artery bypass grafting
- Volunteers
- 6,448 people
- Sponsor
- Medical University of Silesia
Postoperative Kidney Injury
Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients
The purpose of this study is to evaluate the safety of a standard volume replacement called HES 130/0.4 (Voluven) during surgery on recovery.
- Trial name
- SHARP (NCT02192502)
- Testing
- human albumin 5%, HES 130/0.4 (Voluven)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- The Cleveland Clinic
Coronary Artery Bypass Graft
Effect of Deep Breathing Exercises on Post Operative Sleep Duration
This study will provide the evidence that during the postoperative period deep breathing exercise combined with physical training can positively influence the sleep duration and quality.
- Trial name
- NCT05058222
- Testing
- Deep Breathing Exercise after every 3hrs, each session consists of 10 deep breaths Exercise, Deep Breathing Exercise after every 3hrs, each session consist of 30 deep breaths Exercise
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Cardiac Surgical Procedures, Thoracic Surgical Procedures
Pulse Pressure Variation Measured During Valsalva Maneuver to Predict Fluid Responsiveness Under Open-chest Condition
Pulse pressure variation (PPV) is a well-known dynamic preload indicator to predict fluid responsiveness. However, its usefulness in open-chest conditions has been equivocal.
- Conditions
- Cardiac Surgical Procedures, Thoracic Surgical Procedures, Sternotomy
- Trial name
- NCT02457572
- Testing
- Valsalva maneuver, Fluid loading
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Samsung Medical Center
Ascending Aortic Aneurysm, Aortic Adventitial Pathology
Prospective Evaluation of Adventitial Histopathology in Borderline Ascending Aortic Dilatatio
This prospective study investigates microscopic changes in the outer layer (adventitia) of the ascending aorta in patients undergoing coronary artery bypass grafting (CABG) surgery.
- Conditions
- Ascending Aortic Aneurysm, Aortic Adventitial Pathology, Coronary Artery Bypass Grafting (CABG), Borderline Aortic Dilatation
- Trial name
- NCT07034586
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Samsun University
Coronary Artery Disease
MIDCAB Versus DES in Proximal LAD Lesions
Percutaneous coronary intervention with a sirolimus-coated stent compared to minimally invasive bypass surgery in patients with isolated proximal left anterior descending coronary arteries in terms of non-inferiority of an end…
- Trial name
- NCT00299429
- Testing
- Stenting and minimally invasive bypass surgery, PCI with DES
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University of Leipzig
Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients
Effect of Respiratory Trainer on Cardiopulmonary Functions in Patients with Upper Cross Syndrome Post-Cardiac Surgery
The purpose of this study is to investigate if there is any effect of the respiratory training on cardiopulmonary functions in patients with upper cross syndrome post-cardiac surgery.
- Conditions
- Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients, Upper Cross Syndrome, Respiratory Muscle Weakness
- Trial name
- NCT06673953
- Testing
- Respiratory Muscle Training by (The Breather), Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cardiac Surgery
Individualized Blood Pressure Management in Patients Undergoing Cardiac Surgery
This pilot randomized-controlled study will determine the feasibility of large study comparing individualized versus standard blood pressure (BP) management in patients undergoing cardiac surgery under cardiopulmonary bypass…
- Trial name
- PRECISE (NCT03784690)
- Testing
- Individualized intraoperative BP management, Standard intraoperative BP management
- Where
- Russia
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Disease, Coronary Artery Disease
MACBIS50 in Patients Undergoing CAG During Normothermic CPB Phase.
Background: We determined the minimum alveolar concentration (MAC) of sevoflurane for maintaining bispectral index (BIS) below 50 (MACBIS50) in patients undergoing coronary artery bypass grafting during normothermic…
- Trial name
- NCT02711384
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Hyperoxia, Cardiac Surgery
Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study
During surgery high concentrations of supplementary oxygen are routinely administrated. However, there is increasing evidence of potential harm with liberal oxygen therapy.
- Conditions
- Hyperoxia, Cardiac Surgery, Cardiopulmonary Bypass, Acute Lung Injury
- Trial name
- NCT04133740
- Testing
- Oxygen
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Aalborg University Hospital
Coronary Artery Bypass, Off-Pump, Minimally Invasive Cardiac Surgery
MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT04795193
- Testing
- Minimal invasive coronary surgery, Off-pump coronary artery bypass surgery
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Pulmonary Hypertension
Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?
Post-operative pulmonary hypertension is a risk factor for right ventricular failure and an increasing cause of morbidity and mortality in patients undergoing high-risk cardiac surgery.
- Trial name
- NCT00334490
- Testing
- Sildenafil
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Unity Health Toronto
Coronary Artery, Anxiety
The Effect of Diaphragmatic Breathing Exercise on Symptom Severity, Sleep Quality and Anxiety in CABG Patients.
Coronary artery bypass surgery (CABC) is a commonly performed surgical procedure for the treatment of blockages in the heart vessels. This surgical intervention aims to improve the blood circulation of the patients' heart muscle.
- Conditions
- Coronary Artery, Anxiety, Symptom, Sleep
- Trial name
- NCT06356896
- Testing
- diaphragmatic breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- KTO Karatay University
Acute Kidney Injury
The Effect of Ulistin on Acute Renal Injury in Patients Undergoing OPCAB (Off Pump Coronary Artery Bypass): a Propensity Score Matched Study
Acute kidney injury (AKI) is a frequent complication after cardiac surgery. AKI has been reported as 7-40% depending on the type of surgery, and is known to increase to about 50% when there are risk factors.
- Trial name
- NCT04473144
- Testing
- Ulinastatin
- Volunteers
- 500 people
- Sponsor
- Ajou University School of Medicine
Coronary Artery Disease
Prophylactic Administration of Levosimendan in Patients Undergoing Coronary Surgery
The present pilot study aims to investigate the effectiveness of the preoperative infusion of levosimendan in patients with impaired left ventricular function undergoing coronary artery bypass grafting.
- Trial name
- NCT01318460
- Testing
- Levosimendan infusion
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- AHEPA University Hospital
Coronary Artery Bypass
Stroke and Carotid-Cerebral Vascular Disease After CABG
Review the data of patients who underwent coronary artery bypass grafting (CABG) at the Department of Cardiovascular Surgery in Ruijin hospital from March 2020 to May 2022, including medical history, head and neck CTA, head CT…
- Trial name
- SCCAB (NCT05036044)
- Where
- China
- Volunteers
- 1,002 people
- Sponsor
- Ruijin Hospital
Coronary Artery Disease, Diabetes
Predictability of Preoperative Hemoglobin A1c in Diabetic Patients Underwent Off-Pump Coronary Artery Bypass Surgery: A Retrospective Study.
The aim of this study is to evaluate evaluated the impact of preoperative HbA1c in diabetic patients on perioperative glycemic variability and outcome after off-pump coronary artery bypass (OPCAB).
- Trial name
- NCT03543449
- Testing
- Off-Pump Coronary Artery Bypass (OPCAB) surgery
- Where
- South Korea
- Volunteers
- 703 people
- Sponsor
- Yonsei University
Post Cardiac Surgery Systemic Inflammatory Response
Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery
Protocol Summary STUDY DESIGN A pilot, prospective, double blind, randomized, placebo controlled study. STUDY POPULATION Patients assigned to elective CABG with cardiopulmonary bypass (CPB) at the Department of Cardiothoracic…
- Trial name
- NCT02191839
- Testing
- Alpha 1-Antitrypsin
- Volunteers
- 20 people
- Sponsor
- Soroka University Medical Center
Coronary Artery Disease
Remimazolam Besylate and Propofol Sedation on Hemodynamic for Coronary Artery Bypass Graft Patients
In the immediate postoperative period following cardiac surgery, many patients require short-term sedation until cardiovascular and respiratory stability has been achieved and weaning from artificial ventilation can be started.
- Trial name
- NCT06496165
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 338 people
- Sponsor
- Shanghai Zhongshan Hospital