Clinical trials: Cardiac Bypass Patients
Coronary Artery Disease
CT-angiographic Follow up of Patients That Underwent Coronary Bypass Surgery Between 1993-1997
Coronary artery surgery (CABG) is necessary to improve blood circulation in many patients with coronary artery disease. This is done by using alternative blood vessels (grafts) to bypass the stenosed coronary arteries.
- Trial name
- NCT01686100
- Testing
- No touch technique, Conventional technique
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Örebro County Council
Cardiac Surgery, Cardiopulmonary Bypass
Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmonary Bypass
This is a prospective, multicenter, randomized, double-blind, placebo-controlled study. The purpose of this study is to determine the safety and effectiveness of human-derived antithrombin III (AT-III [Human]) supplementation…
- Trial name
- NCT02037555
- Testing
- AT-III (Human)
- Where
- 41 sites in United States
- Volunteers
- 425 people
- Sponsor
- Grifols Therapeutics LLC
Nursing Caries, Music Therapy
The Effect of Complementary Care Model on Patient Outcomes
The study will be carried out in Bolu Abant İzzet Baysal University İzzet Baysal Training and Research Hospital Cardiovascular Surgery Clinic between January 2022 and February 2023.
- Conditions
- Nursing Caries, Music Therapy, Aromatherapy, Preoperative Care
- Trial name
- NCT05446662
- Testing
- music therapy, aromatherapy, Progressive Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Abant Izzet Baysal University
Congestive Heart Failure
BMAC Enhanced Coronary Artery Bypass Grafting (CABG)
Injection of concentrated bone marrow cells into the myocardium during CABG procedure.
- Trial name
- NCT01061580
- Testing
- Harvest SmartPReP2 BMAC System
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Harvest Technologies
Pain, Acute Post-Operative, Anxiety
Effects of Reflexology and Cold Application Before Chest Tube Removal in CABG Patients
This randomized controlled trial evaluated the effects of foot reflexology and cold application, administered separately before chest tube removal, on pain, state anxiety, and physiological parameters in patients following…
- Conditions
- Pain, Acute Post-Operative, Anxiety, Chest Tube Removal, Coronary Artery Bypass
- Trial name
- NCT07528482
- Testing
- Reflexology, Cryotherapy alone
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Coronary Artery Bypass Graft Redo, General Anesthetic Drug Adverse Reaction
The Effect of Desflurane on Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting
This study is to assess the effect of desflurane on myocardial function in patents who underwent coronary artery bypass grafting.
- Trial name
- NCT02213718
- Testing
- Desflurane, propofol, sufentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Huazhong University of Science and Technology
Sedation Complication
Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients Cardiac Surgery
Preoperative, intraoperative and postoperative management of the patient are some of the main stages that can affect the hospital LOS and ICU LOS.
- Trial name
- LOS (NCT05809518)
- Testing
- Propofol injection, Dexmedetomidine injection, Dexmedetomidine and Propofol
- Where
- Ukraine
- Volunteers
- 194 people
- Sponsor
- Anesthesia Research Group UA
Bleeding, Bypass Complication
A Pre-market, Multi-center, International, Double-blind, Randomized, Two-arms, Controlled, Prospective Clinical Investigation Assessing the Safety and Performance of a Medical Device (ClearPlasma™) for the Treatment of Patients Undergoing Coronary Artery Bypass or Valve Replacement
Bleeding is a significant complication in cardiac surgery, with 10-15% of open cardiac surgery patients experiencing major intra- or post-operative bleeding.
- Conditions
- Bleeding, Bypass Complication, Valve Replacement
- Trial name
- NCT05542277
- Testing
- ClearPlasma
- Where
- 8 sites in Czechia, Israel and 1 more
- Volunteers
- 130 people
- Sponsor
- PlasFree Ltd.
Atrial Fibrillation, Heart Failure
Cardiopulmonary Bypass and Ventricular Remodeling
The goal of this observational study is determine if reduced ventricular ejection fraction is a factor that determines a pro-oxidant imbalance in patients subjected to cardiac surgery with cardiopulmonary bypass.
- Trial name
- CBP-VR (NCT06256965)
- Testing
- Detection of peri-operative atrial fibrillation
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- University of Chile
Coronary Artery Disease, Obesity
Structured Physiotherapy Program in Obese and Non-obese Patients
A routine physiotherapy program has been shown to be effective in the prevention and treatment of cardiopulmonary diseases. It also significantly increases functional capacity following coronary artery bypass grafting.
- Trial name
- NCT05357937
- Testing
- standard physiotherapy program
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Jazan
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Acute Kidney Disease, Chronic Kidney Disease
Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney Disease
The protective nitric oxide (NO) effects are mediated by selective pulmonary vasodilation and improvement of arterial oxygenation in hypoxemic patients by reducing intrapulmonary shunting and improving ventilation-perfusion…
- Conditions
- Acute Kidney Disease, Chronic Kidney Disease, Cardiac Surgery, Cardiopulmonary Bypass
- Trial name
- DEFENDER (NCT05757557)
- Testing
- 80-ppm NO
- Where
- Russia
- Volunteers
- 136 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Coronary Artery Disease, Postoperative Pulmonary Complications
Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and Diaphragm Function
Pulmonary atelectasis and loss of lung aeration are common complications following cardiac surgery with cardiopulmonary bypass (CPB) and are associated with impaired oxygenation and prolonged mechanical ventilation.
- Conditions
- Coronary Artery Disease, Postoperative Pulmonary Complications, Pulmonary Atelectasis, Postoperative, Diaphragm Dysfunction
- Trial name
- FCV-PCV-DTI-LU (NCT07800741)
- Testing
- Flow-Controlled Ventilation, Pressure-Controlled Ventilation (PCV)
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Hypertrophic Obstructive Cardiomyopathy
Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy
Perioperative blockage of beta-adrenoreceptors is widely used in cardiac and non-cardiac surgery to reduce the rate of cardiovascular complications.
- Trial name
- NCT05073094
- Testing
- Esmolol
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Chronic Obstructive Pulmonary Disease, Cardiac Surgery
Chronic Obstructive Pulmonary Disease as a Predictor of Mortality in Cardiac Surgery
To estimate prevalence of chronic obstructive pulmonary disease (COPD) in cardiac surgery population and establish links between COPD status, as assessed through pulmonary functional tests, and 2-year mortality
- Trial name
- NCT02392065
- Where
- Russia
- Volunteers
- 1,100 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Bypass Grafting
The Effect of Intranasally Administered Nitroglycerin on Hemodynamic Response to Laryngoscopy and Intubation Among Patients Undergoing Coronary Artery Bypass Grafting (CABG) Surgery
Numerous preventive medications have been used to lessen the cardiovascular response to laryngoscopy and intubation. Though some advantages have been noted, most of these treatments have not been found to be completely…
- Trial name
- NCT06637956
- Testing
- Nitroglycerin (NTG)
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Muhammad Aamir Latif
Intraocular Pressure, Anesthesia
Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardiopulmonary Bypass
The aim of the study to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia on intraocular pressure (IOP) during coronary artery bypass graft surgery (CABG) with cardiopulmonary…
- Trial name
- NCT06494969
- Testing
- Intraocular pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Antalya Training and Research Hospital
CABG
Dexmedetomidine vs Control on Attenuation Hemodynamic Response to Noxious Stimuli in CABG Surgical Patients
Aim to study efficacy of dexmedetomidine to attenuate hemodynamic response to intubation, skin incision, sternotomy and aortic cannulation
- Trial name
- CABG (NCT06238011)
- Testing
- Dexmedetomidine, Normal saline
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Sawanpracharak hospital
Pain, Postoperative, Sleep Disturbance
The Effect of Foot Massage After Open Heart Surgery on Postoperative Pain, Sleep Quality and Mood of Patients
The randomized controlled experimental study was conducted in the cardiovascular surgery clinic of Atatürk University Health Practice and Research Center between April 2021 and September 2021.The research sample consisted of 91…
- Conditions
- Pain, Postoperative, Sleep Disturbance, Mood, Bypass Complication
- Trial name
- NCT05567107
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Postoperative Complications
Cardiac Surgery and Postoperative Organ Dysfunction
The aim of the study is to identify the correlation between ischaemia reperfusion injury and postoperative multiorgan damage during cardiopulmonary cardiac surgery; and to investigate biomarkers that can predict postoperative…
- Trial name
- NCT05529212
- Testing
- ischemic reperfusion injury
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University